PMID- 31330468
OWN - NLM
STAT- MEDLINE
DCOM- 20201102
LR  - 20201102
IS  - 1873-6327 (Electronic)
IS  - 0306-4603 (Print)
IS  - 0306-4603 (Linking)
VI  - 98
DP  - 2019 Nov
TI  - Nicotine in thirdhand smoke residue predicts relapse from smoking cessation: A 
      pilot study.
PG  - 106041
LID - S0306-4603(19)30427-7 [pii]
LID - 10.1016/j.addbeh.2019.106041 [doi]
AB  - INTRODUCTION: Thirdhand smoke (THS) residue lingers for months in homes of former 
      smokers and may play a role in relapse after smoking cessation. This study 
      examined the association between THS pollution as measured by the level of 
      nicotine in house dust and continued abstinence from smoking. METHODS: 
      Participants were 65 cigarette smokers who reported they were enrolled in any 
      type of smoking cessation program, had set a specific date to quit, and had 
      biochemical verification of continuous abstinence at 1-week (W1), 1-month (M1), 
      3-months (M3), or 6-months (M6) after their quit date. House dust samples 
      collected at baseline before quitting were analyzed for nicotine concentration 
      (mug/g) and nicotine loading (mug/m(2)) using liquid chromatography-tandem mass 
      spectrometry (LC-MS/MS). RESULTS: Controlling for age, gender, overall and indoor 
      smoking rates, and years lived in their home, dust nicotine concentration and 
      loading predicted abstinence at W1, M1, M3, and M6. A 10-fold increase in dust 
      nicotine loading and concentration were associated with approximately 50% lower 
      odds of remaining abstinent. CONCLUSIONS: Findings suggest nicotine in house dust 
      may play a role in facilitating relapse after smoking cessation. Additional 
      research is warranted to investigate the causal role of THS residue in homes of 
      former smokers on cravings and continued abstinence.
CI  - Copyright (c) 2019. Published by Elsevier Ltd.
FAU - Matt, Georg E
AU  - Matt GE
AD  - San Diego State University, Department of Psychology, San Diego, CA, USA. 
      Electronic address: gmatt@sdsu.edu.
FAU - Mahabee-Gittens, E Melinda
AU  - Mahabee-Gittens EM
AD  - Cincinnati Children's Hospital Medical Center, University of Cincinnati College 
      of Medicine, Cincinnati, OH, USA.
FAU - Zakarian, Joy M
AU  - Zakarian JM
AD  - San Diego State University Research Foundation, San Diego, CA, USA.
FAU - Quintana, Penelope J E
AU  - Quintana PJE
AD  - San Diego State University, School of Public Health, San Diego, CA, USA.
FAU - Hoh, Eunha
AU  - Hoh E
AD  - San Diego State University, School of Public Health, San Diego, CA, USA.
FAU - Myers, Mark
AU  - Myers M
AD  - Veterans Administration San Diego Healthcare System and Department of Psychiatry, 
      University of California, San Diego, CA, USA.
LA  - eng
GR  - R01 ES027815/ES/NIEHS NIH HHS/United States
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20190702
PL  - England
TA  - Addict Behav
JT  - Addictive behaviors
JID - 7603486
RN  - 0 (Dust)
RN  - 0 (Tobacco Smoke Pollution)
RN  - 6M3C89ZY6R (Nicotine)
SB  - IM
MH  - Adult
MH  - Air Pollution, Indoor/*adverse effects/*analysis
MH  - California
MH  - Chromatography, Liquid
MH  - Dust/*analysis
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Nicotine/*adverse effects
MH  - Pilot Projects
MH  - Recurrence
MH  - *Smoking Cessation
MH  - Tandem Mass Spectrometry
MH  - Tobacco Smoke Pollution/*adverse effects/analysis
PMC - PMC6745712
MID - NIHMS1049683
OTO - NOTNLM
OT  - Nicotine
OT  - Relapse
OT  - Smoking cessation
OT  - Thirdhand smoke
COIS- Declaration of Competing Interests The authors declare that they have no 
      conflicts of interest.
EDAT- 2019/07/23 06:00
MHDA- 2020/11/03 06:00
PMCR- 2019/11/01
CRDT- 2019/07/23 06:00
PHST- 2019/04/11 00:00 [received]
PHST- 2019/06/27 00:00 [revised]
PHST- 2019/07/01 00:00 [accepted]
PHST- 2019/07/23 06:00 [pubmed]
PHST- 2020/11/03 06:00 [medline]
PHST- 2019/07/23 06:00 [entrez]
PHST- 2019/11/01 00:00 [pmc-release]
AID - S0306-4603(19)30427-7 [pii]
AID - 10.1016/j.addbeh.2019.106041 [doi]
PST - ppublish
SO  - Addict Behav. 2019 Nov;98:106041. doi: 10.1016/j.addbeh.2019.106041. Epub 2019 
      Jul 2.