PMID- 31336549 OWN - NLM STAT- MEDLINE DCOM- 20191227 LR - 20191227 IS - 1878-0334 (Electronic) IS - 1871-4021 (Linking) VI - 13 IP - 2 DP - 2019 Mar-Apr TI - Quality of life in subjects with type 2 diabetes mellitus with diabetic retinopathy: A case-control study. PG - 947-952 LID - S1871-4021(18)30569-1 [pii] LID - 10.1016/j.dsx.2018.12.012 [doi] AB - AIMS: Diabetic retinopathy (DR) as a common complication of Type 2 Diabetes Mellitus (T2DM) affecting negatively quality of life (QoL). Assessing of QoL in patients with DR is a prerequisite for the evaluation of their needs and for understanding the perception of the patients themselves about their health status and how the disease affects their lives. Additionally, QoL indicators detect individual psychosocial problems that may impact therapeutic response. MATERIALS AND METHODS: A total of 70 subjects with T2DM and DR as well as 70 T2DM individuals without DR were included. For the evaluation of QoL we used (a) WHO QoL - BREF for the estimation of QoL, (b) Life Satisfaction Scale for the estimation of satisfaction from life, and (c) the special recording document for demographic, socioeconomic, and clinical data. At the same time, blood was collected for the measurement of glucose control and renal function. DR was diagnosed by dilated fundoscopy. RESULTS: Patients with DR had significantly worse scores in all scales of QoL and Life Satisfaction in comparison with those without DR. We found significant impact of the severity of DR in many domains of the QoL and Life Satisfaction. Multivariate logistic regression analysis demonstrated that DR was associated with worse QoL and Life Satisfaction scores as well as lower income, while no significant associations were found with education level, family, insurance and employment status as well as type of residence. CONCLUSION: DR affects QoL and Life Satisfaction and is associated with lower income. CI - Copyright (c) 2019 Diabetes India. Published by Elsevier Ltd. All rights reserved. FAU - Ligda, Georgia AU - Ligda G AD - Department of Psychiatry, Sismanoglio General Hospital, Athens, Greece. Electronic address: georgialig@yahoo.gr. FAU - Ploubidis, Dimitrios AU - Ploubidis D AD - First Psychiatric Department, Medical School, National and Kapodistrian University of Athens, Greece, Athens. FAU - Foteli, Stefania AU - Foteli S AD - Evangelismos, General Hospital, Department of Psychiatry, Athens, Greece. FAU - Kontou, Panagiota I AU - Kontou PI AD - Department of Computer Science and Biomedical Informatics, University of Thessaly, Greece. FAU - Nikolaou, Chrysoula AU - Nikolaou C AD - Department of Medical Biopathology - Psychoimmunology, Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece. FAU - Tentolouris, Nikolaos AU - Tentolouris N AD - First Department of Propaedeutic Internal Medicine, Medical School, National and Kapodistrian University of Athens, Laiko General Hospital, Athens, Greece. LA - eng PT - Journal Article PT - Observational Study DEP - 20181220 PL - Netherlands TA - Diabetes Metab Syndr JT - Diabetes & metabolic syndrome JID - 101462250 SB - IM MH - Adolescent MH - Adult MH - Aged MH - Case-Control Studies MH - Cross-Sectional Studies MH - Diabetes Mellitus, Type 2/*complications MH - Diabetic Retinopathy/etiology/*psychology/*therapy MH - Female MH - Follow-Up Studies MH - Health Status MH - Humans MH - Male MH - Middle Aged MH - Patient Satisfaction/*statistics & numerical data MH - Prognosis MH - *Quality of Life MH - Surveys and Questionnaires MH - Young Adult OTO - NOTNLM OT - Diabetic retinopathy OT - Life satisfaction OT - Quality of life OT - Type 2 diabetes mellitus OT - WHOQOL-BREF EDAT- 2019/07/25 06:00 MHDA- 2019/12/28 06:00 CRDT- 2019/07/25 06:00 PHST- 2018/11/23 00:00 [received] PHST- 2018/12/19 00:00 [accepted] PHST- 2019/07/25 06:00 [entrez] PHST- 2019/07/25 06:00 [pubmed] PHST- 2019/12/28 06:00 [medline] AID - S1871-4021(18)30569-1 [pii] AID - 10.1016/j.dsx.2018.12.012 [doi] PST - ppublish SO - Diabetes Metab Syndr. 2019 Mar-Apr;13(2):947-952. doi: 10.1016/j.dsx.2018.12.012. Epub 2018 Dec 20.