PMID- 31346993
OWN - NLM
STAT- MEDLINE
DCOM- 20191226
LR  - 20210110
IS  - 2523-899X (Electronic)
IS  - 2523-899X (Linking)
VI  - 39
IP  - 4
DP  - 2019 Aug
TI  - Thyroid Nodules in Type 2 Diabetes Mellitus.
PG  - 576-581
LID - 10.1007/s11596-019-2076-5 [doi]
AB  - The present analysis aims to investigate the prevalence of thyroid nodules in 
      type 2 diabetes mellitus (T2DM) population. We searched PubMed, EMBASE, and Web 
      of Science from inception to the March 1, 2018. The studies were selected to 
      estimate the prevalence of thyroid nodules in T2DM subjects and to compare the 
      prevalence of thyroid nodules in different glucose tolerance status. The random 
      effects model was used, and the outcome was presented as a pooled prevalence 
      proportion with 95% confidence interval (95% CI) or a summary odds ratio (OR) 
      with 95% CI. In the end, 9 studies met the inclusion criteria and were included 
      in the analysis. The pooled prevalence of thyroid nodules was 60% (95% CI: 0.52, 
      0.68) for T2DM 2 diabetes patients, 50% (95% CI: 0.48, 0.51) for pre-diabetes, 
      and 43% (95% CI: 0.34, 0.52) for normal glucose tolerance population. Compared 
      with patients without diabetes, diabetes subjects are more likely to develop 
      thyroid nodules, adjusted OR for thyroid nodule was 1.78 (95% CI: 1.25, 2.55). 
      Insulin resistance might be involved in thyroid nodule development.
FAU - Zhang, Hong-Mei
AU  - Zhang HM
AD  - Department of Endocrinology, Xinhua Hospital, School of Medicine, Shanghai 
      Jiaotong University, Shanghai, 200092, China.
FAU - Feng, Qi-Wen
AU  - Feng QW
AD  - Department of Endocrinology, Xinhua Hospital, School of Medicine, Shanghai 
      Jiaotong University, Shanghai, 200092, China.
FAU - Niu, Yi-Xin
AU  - Niu YX
AD  - Department of Endocrinology, Xinhua Hospital, School of Medicine, Shanghai 
      Jiaotong University, Shanghai, 200092, China.
FAU - Su, Qing
AU  - Su Q
AD  - Department of Endocrinology, Xinhua Hospital, School of Medicine, Shanghai 
      Jiaotong University, Shanghai, 200092, China. suqing@xinhuamed.com.cn.
FAU - Wang, Xia
AU  - Wang X
AD  - The George Institute for Global Health and Royal Prince Alfred Hospital, the 
      University of Sydney, Sydney, NSW, 2050, Australia. xwang@georgeinstitute.org.au.
LA  - eng
PT  - Journal Article
DEP - 20190725
PL  - China
TA  - Curr Med Sci
JT  - Current medical science
JID - 101729993
SB  - IM
MH  - Adult
MH  - Diabetes Mellitus, Type 2/complications/*diagnosis/pathology
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Odds Ratio
MH  - Prevalence
MH  - Thyroid Nodule/complications/*diagnosis/pathology
OTO - NOTNLM
OT  - diabetes
OT  - insulin resistance
OT  - thyroid nodule
EDAT- 2019/07/28 06:00
MHDA- 2019/12/27 06:00
CRDT- 2019/07/27 06:00
PHST- 2018/09/28 00:00 [received]
PHST- 2019/06/05 00:00 [revised]
PHST- 2019/07/27 06:00 [entrez]
PHST- 2019/07/28 06:00 [pubmed]
PHST- 2019/12/27 06:00 [medline]
AID - 10.1007/s11596-019-2076-5 [pii]
AID - 10.1007/s11596-019-2076-5 [doi]
PST - ppublish
SO  - Curr Med Sci. 2019 Aug;39(4):576-581. doi: 10.1007/s11596-019-2076-5. Epub 2019 
      Jul 25.