PMID- 31347165
OWN - NLM
STAT- MEDLINE
DCOM- 20201231
LR  - 20201231
IS  - 1097-0010 (Electronic)
IS  - 0022-5142 (Linking)
VI  - 100
IP  - 11
DP  - 2020 Aug 30
TI  - A Khorasan wheat-based diet improves systemic inflammatory profile in 
      semi-professional basketball players: a randomized crossover pilot study.
PG  - 4101-4107
LID - 10.1002/jsfa.9947 [doi]
AB  - BACKGROUND/OBJECTIVES: Khorasan wheat is an ancient grain with widely acclaimed 
      beneficial effects on human health. The objective of the study was to examine the 
      effect of a Khorasan-based diet on the wellbeing and inflammatory profile of 
      young athletes. RESULTS: We conducted a randomized, single-blinded crossover 
      trial involving 20 male young athletes. The participants were randomly assigned 
      to consume products (pasta, bread, biscuits and crackers) made either with 
      Khorasan (KAMUT(R) brand) or modern semi-whole-grain wheat for 4-weeks with a 
      4-week washout period before the crossover. Laboratory analyses and fitness tests 
      were performed both at the beginning and end of each diet period. The consumption 
      of Khorasan products was associated with a significant reduction of monocyte 
      chemoattractant protein-1 (MCP-1; mean reduction: -36.15 pg/mL; -25.67%) while 
      the consumption of modern wheat was not associated with significant differences 
      in Interleukin-8 (IL-8) or Interleukin-1 receptor antagonist (IL-1ra). The 
      consumption of the Khorasan-based diet also resulted in a significant improvement 
      in self-rated health status. No statistically significant differences in any 
      athletic performance parameter were observed between the two diets. CONCLUSION: 
      The present results suggest that a Khorasan-based diet could be effective in 
      reducing the inflammatory status in young athletes. (c) 2019 Society of Chemical 
      Industry.
CI  - (c) 2019 Society of Chemical Industry.
FAU - Spisni, Enzo
AU  - Spisni E
AUID- ORCID: 0000-0002-8525-2981
AD  - Department of Biological, Geological and Environmental Sciences, University of 
      Bologna, Bologna, Italy.
FAU - Valerii, Maria Chiara
AU  - Valerii MC
AD  - Department of Biological, Geological and Environmental Sciences, University of 
      Bologna, Bologna, Italy.
FAU - De Fazio, Luigia
AU  - De Fazio L
AD  - Department of Biological, Geological and Environmental Sciences, University of 
      Bologna, Bologna, Italy.
FAU - Rotondo, Enrica
AU  - Rotondo E
AD  - Department of Biological, Geological and Environmental Sciences, University of 
      Bologna, Bologna, Italy.
FAU - Di Natale, Marcella
AU  - Di Natale M
AD  - Department of Biological, Geological and Environmental Sciences, University of 
      Bologna, Bologna, Italy.
FAU - Giovanardi, Elisabetta
AU  - Giovanardi E
AD  - Department of Biological, Geological and Environmental Sciences, University of 
      Bologna, Bologna, Italy.
FAU - Posabella, Giovanni
AU  - Posabella G
AD  - BioSportMed, Bologna, Italy.
FAU - Bregola, Valeria
AU  - Bregola V
AD  - Department of Agricultural Sciences, University of Bologna, Bologna, Italy.
FAU - Stenico, Verena
AU  - Stenico V
AD  - Department of Agricultural Sciences, University of Bologna, Bologna, Italy.
FAU - Sferrazza, Rocco Enrico
AU  - Sferrazza RE
AD  - Department of Agricultural Sciences, University of Bologna, Bologna, Italy.
FAU - Dinelli, Giovanni
AU  - Dinelli G
AD  - Department of Agricultural Sciences, University of Bologna, Bologna, Italy.
FAU - Bosi, Sara
AU  - Bosi S
AUID- ORCID: 0000-0003-2722-8390
AD  - Department of Agricultural Sciences, University of Bologna, Bologna, Italy.
LA  - eng
GR  - 04/2016 to Giovanni Dinelli/Kamut Enterprises of Europe (KEE) Oudenaarde, 
      Belgium/
GR  - University of Bologna RFO 2016 Grant to Enzo Spisn/Universita di Bologna/
PT  - Journal Article
PT  - Randomized Controlled Trial
DEP - 20190831
PL  - England
TA  - J Sci Food Agric
JT  - Journal of the science of food and agriculture
JID - 0376334
RN  - 0 (Interleukin-8)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Athletic Performance
MH  - Basketball/physiology
MH  - Cross-Over Studies
MH  - Diet
MH  - Humans
MH  - Inflammation/blood/*diet therapy/prevention & control
MH  - Interleukin-8/blood/immunology
MH  - Male
MH  - Pilot Projects
MH  - Triticum/*metabolism
MH  - Young Adult
OTO - NOTNLM
OT  - Ancient grains
OT  - Diet
OT  - Inflammation
OT  - Sport activity
EDAT- 2019/07/28 06:00
MHDA- 2021/01/01 06:00
CRDT- 2019/07/27 06:00
PHST- 2019/02/08 00:00 [received]
PHST- 2019/04/29 00:00 [revised]
PHST- 2019/07/23 00:00 [accepted]
PHST- 2019/07/28 06:00 [pubmed]
PHST- 2021/01/01 06:00 [medline]
PHST- 2019/07/27 06:00 [entrez]
AID - 10.1002/jsfa.9947 [doi]
PST - ppublish
SO  - J Sci Food Agric. 2020 Aug 30;100(11):4101-4107. doi: 10.1002/jsfa.9947. Epub 
      2019 Aug 31.