PMID- 31352098
OWN - NLM
STAT- MEDLINE
DCOM- 20191220
LR  - 20191220
IS  - 1879-1298 (Electronic)
IS  - 0045-6535 (Linking)
VI  - 237
DP  - 2019 Dec
TI  - Evaluation of the effectiveness of different indicator PCBs to estimating total 
      PCB concentrations in environmental investigations.
PG  - 124429
LID - S0045-6535(19)31650-9 [pii]
LID - 10.1016/j.chemosphere.2019.124429 [doi]
AB  - Polychlorinated biphenyls (PCBs) are one of the most widely studied group of 
      persistent organic pollutants (POPs). There are 209 different PCBs, however not 
      all 209 can currently be individually quantified in one analytical run. This 
      means that a subset of PCBs congeners are often determined and reported. Some of 
      the most commonly reported subsets are the 7 indicator PCBs (28, 52, 101, 118, 
      138, 153 and 180) and the WHO 12 PCBs (77, 81, 105, 114, 118, 123, 126, 156, 157, 
      167, 169 and 189). The WHO 12 congeners are co-planar 'dioxin like' PCBs that are 
      effective for establishing health risks. The 7 indicator PCBs were selected as 
      some of the most common PCBs across the compositional range of the most common 
      technical mixtures (such as Aroclors), and are used to give an indication of the 
      total PCB concentrations. These groups of indicator PCBs were established several 
      decades ago. However, in the environment commercial mixtures are subject to 
      weathering and fractionation processes, and additional sources of non-Aroclor 
      PCBs are also becoming more important. In this manuscript we use existing large 
      scale comprehensive congener specific datasets to evaluate the effectiveness of 
      indicator PCBs to predict total concentrations and establish if they are still 
      fit for purpose. The results indicate that while these traditional indicators are 
      a useful tool to estimate total concentrations in humans with background exposure 
      there are many instances where they are not fit for purpose and can lead to 
      significant under predictions in total PCB concentrations in environmental 
      matrices.
CI  - Copyright (c) 2019 Elsevier Ltd. All rights reserved.
FAU - Megson, David
AU  - Megson D
AD  - Manchester Metropolitan University, Ecology and Environment Research Centre, 
      Manchester, UK; Chemistry Matters Inc., Alberta, Canada. Electronic address: 
      d.megson@mmu.ac.uk.
FAU - Benoit, Nadine B
AU  - Benoit NB
AD  - Ontario Ministry of the Environment Conservation and Parks, Toronto, ON, Canada.
FAU - Sandau, Courtney D
AU  - Sandau CD
AD  - Chemistry Matters Inc., Alberta, Canada; Mount Royal University, Department of 
      Earth and Environmental Sciences, Faculty of Science and Technology, 4825, Mount 
      Royal Gate SW, Calgary, AB, Canada.
FAU - Chaudhuri, Sri R
AU  - Chaudhuri SR
AD  - Ontario Ministry of the Environment Conservation and Parks, Toronto, ON, Canada.
FAU - Long, Tanya
AU  - Long T
AD  - Ontario Ministry of the Environment Conservation and Parks, Toronto, ON, Canada.
FAU - Coulthard, Emma
AU  - Coulthard E
AD  - Manchester Metropolitan University, Ecology and Environment Research Centre, 
      Manchester, UK.
FAU - Johnson, Glenn W
AU  - Johnson GW
AD  - University of Utah, Salt Lake City, UT, 84108, USA.
LA  - eng
PT  - Journal Article
DEP - 20190722
PL  - England
TA  - Chemosphere
JT  - Chemosphere
JID - 0320657
RN  - 0 (Aroclors)
RN  - 0 (Dioxins)
RN  - 0 (Environmental Pollutants)
RN  - 0 (Indicators and Reagents)
RN  - DFC2HB4I0K (Polychlorinated Biphenyls)
SB  - IM
MH  - Aroclors/analysis
MH  - Dioxins/analysis
MH  - Environmental Exposure/analysis
MH  - Environmental Monitoring/*methods
MH  - Environmental Pollutants/*analysis
MH  - Humans
MH  - Indicators and Reagents
MH  - Polychlorinated Biphenyls/*analysis
OTO - NOTNLM
OT  - Aroclors
OT  - Humans
OT  - PCBs
OT  - Polychlorinated biphenyls
OT  - Sediments
OT  - Water
EDAT- 2019/07/29 06:00
MHDA- 2019/12/21 06:00
CRDT- 2019/07/29 06:00
PHST- 2019/02/28 00:00 [received]
PHST- 2019/07/16 00:00 [revised]
PHST- 2019/07/21 00:00 [accepted]
PHST- 2019/07/29 06:00 [pubmed]
PHST- 2019/12/21 06:00 [medline]
PHST- 2019/07/29 06:00 [entrez]
AID - S0045-6535(19)31650-9 [pii]
AID - 10.1016/j.chemosphere.2019.124429 [doi]
PST - ppublish
SO  - Chemosphere. 2019 Dec;237:124429. doi: 10.1016/j.chemosphere.2019.124429. Epub 
      2019 Jul 22.