PMID- 31357598
OWN - NLM
STAT- MEDLINE
DCOM- 20200120
LR  - 20211211
IS  - 2072-6643 (Electronic)
IS  - 2072-6643 (Linking)
VI  - 11
IP  - 8
DP  - 2019 Jul 27
TI  - Low-Carbohydrate Diets for Gestational Diabetes.
LID - 10.3390/nu11081737 [doi]
LID - 1737
AB  - Nutrition therapy provides the foundation for treatment of gestational diabetes 
      (GDM), and has historically been based on restricting carbohydrate (CHO) intake. 
      In this paper, randomized controlled trials (RCTs) are reviewed to assess the 
      effects of both low- and higher CHO nutrition approaches in GDM. The prevailing 
      pattern across the evidence underscores that although CHO restriction improves 
      glycemia at least in the short-term, similar outcomes could be achievable using 
      less restrictive approaches that may not exacerbate IR. The quality of existing 
      studies is limited, in part due to dietary non-adherence and confounding effects 
      of treatment with insulin or oral medication. Recent evidence suggests that 
      modified nutritional manipulation in GDM from usual intake, including but not 
      limited to CHO restriction, improves maternal glucose and lowers infant 
      birthweight. This creates a platform for future studies to further clarify the 
      impact of multiple nutritional patterns in GDM on both maternal and infant 
      outcomes.
FAU - Farabi, Sarah S
AU  - Farabi SS
AD  - Goldfarb School of Nursing, Office of Nursing Research, Barnes-Jewish College, 
      St. Louis, MO 63110, USA.
AD  - Department of Medicine, Division of Nutritional Science, Washington University in 
      St. Louis, St. Louis, MO 63130, USA.
FAU - Hernandez, Teri L
AU  - Hernandez TL
AUID- ORCID: 0000-0002-7024-5017
AD  - Department of Medicine, Division of Endocrinology, Metabolism, and Diabetes, 
      Anschutz Medical Campus, University of Colorado, Aurora, CO 80045, USA. 
      Teri.Hernandez@CUAnschutz.edu.
AD  - College of Nursing, Anschutz Medical Campus, University of Colorado, Aurora, CO 
      80045, USA. Teri.Hernandez@CUAnschutz.edu.
AD  - Department of Research, Innovation, and Professional Practice, Children's 
      Hospital Colorado, Anschutz Medical Campus, University of Colorado, Aurora, CO 
      80045, USA. Teri.Hernandez@CUAnschutz.edu.
LA  - eng
GR  - P30 DK056341/DK/NIDDK NIH HHS/United States
GR  - R01 DK101659/DK/NIDDK NIH HHS/United States
GR  - R01 DK101659/NH/NIH HHS/United States
PT  - Journal Article
PT  - Review
DEP - 20190727
PL  - Switzerland
TA  - Nutrients
JT  - Nutrients
JID - 101521595
RN  - 0 (Dietary Carbohydrates)
SB  - IM
MH  - Diabetes, Gestational/diagnosis/*diet therapy/epidemiology/physiopathology
MH  - *Diet, Carbohydrate-Restricted/adverse effects
MH  - Dietary Carbohydrates/*administration & dosage/adverse effects/metabolism
MH  - Female
MH  - Gestational Weight Gain
MH  - Humans
MH  - Incidence
MH  - Maternal Nutritional Physiological Phenomena
MH  - Nutritional Status
MH  - Obesity/diagnosis/*diet therapy/epidemiology/physiopathology
MH  - Pregnancy
MH  - Prevalence
MH  - Randomized Controlled Trials as Topic
MH  - Risk Factors
MH  - Treatment Outcome
PMC - PMC6723585
OTO - NOTNLM
OT  - diet
OT  - gestational diabetes
OT  - low-CHO
OT  - nutrition
OT  - obesity
OT  - pregnancy
COIS- The authors declare no conflict of interest.
EDAT- 2019/07/31 06:00
MHDA- 2020/01/21 06:00
PMCR- 2019/08/01
CRDT- 2019/07/31 06:00
PHST- 2019/06/17 00:00 [received]
PHST- 2019/07/12 00:00 [revised]
PHST- 2019/07/23 00:00 [accepted]
PHST- 2019/07/31 06:00 [entrez]
PHST- 2019/07/31 06:00 [pubmed]
PHST- 2020/01/21 06:00 [medline]
PHST- 2019/08/01 00:00 [pmc-release]
AID - nu11081737 [pii]
AID - nutrients-11-01737 [pii]
AID - 10.3390/nu11081737 [doi]
PST - epublish
SO  - Nutrients. 2019 Jul 27;11(8):1737. doi: 10.3390/nu11081737.