PMID- 31359566
OWN - NLM
STAT- MEDLINE
DCOM- 20200213
LR  - 20200213
IS  - 1865-1682 (Electronic)
IS  - 1865-1674 (Linking)
VI  - 66
IP  - 6
DP  - 2019 Nov
TI  - Strongyloides stercoralis infection in human immunodeficiency virus-infected 
      patients and related risk factors: A systematic review and meta-analysis.
PG  - 2233-2243
LID - 10.1111/tbed.13310 [doi]
AB  - Strongyloidiasis is caused by nematode infections of the genus Strongyloides, 
      mainly Strongyloides stercoralis, and affects tens of millions of people around 
      the world. S. stercoralis hyperinfection and disseminated strongyloidiasis are 
      unusual but potentially fatal conditions mostly due to Gram-negative bacteremia 
      and sepsis, primarily affecting immunocompromised patients. Infections with 
      immunosuppressive viruses such as human immunodeficiency virus (HIV) and Human 
      T-cell leucemia virus type 1 (HTLV-1) have been reported as risk factors for 
      strongyloidiasis. Hyperinfection syndrome has been described in HIV-positive 
      patients following the use of corticosteroids or during immune reconstitution 
      inflammatory syndrome (IRIS). In this research, we conducted a global systematic 
      review and meta-analysis to assess the seroprevalence and odds ratios (ORs) of 
      S. stercoralis infections in HIV-infected patients. A total of 3,649 records were 
      screened, 164 studies were selected and evaluated in more detail, and 94 studies 
      were included in the meta-analysis. The overall pooled prevalence of 
      S. stercoralis infection in HIV positive patients was 5.1% (CI95%: 4%-6.3%), and 
      a meta-analysis on six studies showed that with a pooled OR of 1.79 (CI95%: 
      1.18%-2.69%) HIV-positive men are at a higher risk of S. stercoralis infections 
      (p < .0052) compared to HIV positive women.
CI  - (c) 2019 Blackwell Verlag GmbH.
FAU - Ahmadpour, Ehsan
AU  - Ahmadpour E
AUID- ORCID: 0000-0003-1202-6147
AD  - Infectious and Tropical Diseases Research Center, Tabriz University of Medical 
      Sciences, Tabriz, Iran.
AD  - Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
FAU - Ghanizadegan, Mohammad Ali
AU  - Ghanizadegan MA
AD  - Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran.
FAU - Razavi, Atefeh
AU  - Razavi A
AD  - Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran.
FAU - Kangari, Mahsa
AU  - Kangari M
AD  - Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran.
FAU - Seyfi, Rouhollah
AU  - Seyfi R
AD  - Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran.
FAU - Shahdust, Maryam
AU  - Shahdust M
AD  - Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran.
FAU - Yazdanian, Ali
AU  - Yazdanian A
AD  - Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran.
FAU - Safarpour, Hanie
AU  - Safarpour H
AD  - Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran.
FAU - Bannazadeh Baghi, Hossein
AU  - Bannazadeh Baghi H
AD  - Infectious and Tropical Diseases Research Center, Tabriz University of Medical 
      Sciences, Tabriz, Iran.
AD  - Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
FAU - Zarean, Mehdi
AU  - Zarean M
AD  - Department of Parasitology and Mycology, Faculty of Medicine, Mashhad University 
      of Medical Sciences, Mashhad, Iran.
FAU - Hosseini, Seyed Abdollah
AU  - Hosseini SA
AD  - Toxoplasmosis Research Center, Mazandaran University of Medical Sciences, Sari, 
      Iran.
FAU - Norouzi, Roghayeh
AU  - Norouzi R
AD  - Department of Pathobiology, Faculty of Veterinary Medicine, University of Tabriz, 
      Tabriz, Iran.
FAU - Ebrahimi, Mina
AU  - Ebrahimi M
AD  - Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, 
      Iran.
FAU - Bangoura, Berit
AU  - Bangoura B
AD  - Department of Veterinary Sciences, College of Agriculture and Natural Resources, 
      University of Wyoming, Laramie, WY, USA.
LA  - eng
PT  - Journal Article
PT  - Meta-Analysis
PT  - Systematic Review
DEP - 20190811
PL  - Germany
TA  - Transbound Emerg Dis
JT  - Transboundary and emerging diseases
JID - 101319538
SB  - IM
MH  - Animals
MH  - HIV Infections/*complications
MH  - Humans
MH  - *Immunocompromised Host
MH  - Prevalence
MH  - Risk Factors
MH  - Sex Factors
MH  - Strongyloides stercoralis
MH  - Strongyloidiasis/*complications
OTO - NOTNLM
OT  - human immunodeficiency virus
OT  - prevalence
OT  - strongyloidiasis
OT  - systematic review
EDAT- 2019/07/31 06:00
MHDA- 2020/02/14 06:00
CRDT- 2019/07/31 06:00
PHST- 2019/05/16 00:00 [received]
PHST- 2019/07/23 00:00 [revised]
PHST- 2019/07/24 00:00 [accepted]
PHST- 2019/07/31 06:00 [pubmed]
PHST- 2020/02/14 06:00 [medline]
PHST- 2019/07/31 06:00 [entrez]
AID - 10.1111/tbed.13310 [doi]
PST - ppublish
SO  - Transbound Emerg Dis. 2019 Nov;66(6):2233-2243. doi: 10.1111/tbed.13310. Epub 
      2019 Aug 11.