PMID- 31364777
OWN - NLM
STAT- MEDLINE
DCOM- 20200702
LR  - 20200702
IS  - 1943-3670 (Electronic)
IS  - 0022-3492 (Linking)
VI  - 91
IP  - 1
DP  - 2020 Jan
TI  - Poor oral hygiene is associated with the detection of obligate anaerobes in 
      pneumonia.
PG  - 65-73
LID - 10.1002/JPER.19-0043 [doi]
AB  - BACKGROUND: Oral cavity is a reservoir of various respiratory pathogens, and poor 
      oral hygiene is associated with an increase in anaerobic bacteria in oral cavity. 
      In addition, it positively relates higher risk of developing pneumonia and 
      increased pneumonia-related mortality. However, the association between poor oral 
      hygiene and increase in obligate anaerobes in the lungs of pneumonia patients is 
      unclear. METHODS: A total of 39 patients with pneumonia in whom bronchoscopic 
      examination and oral hygiene evaluation were performed were prospectively 
      enrolled. The microbiota of the bronchoalveolar lavage fluid (BALF) directly 
      obtained from the pneumonia lesion was analysed by the clone library analysis. In 
      addition, oral hygiene evaluations were performed using oral hygiene index (OHI), 
      tongue coating score, oral dryness, and community periodontal index of treatment 
      needs (CPITN). The association between the detection of oral streptococci and 
      obligate anaerobes and oral hygiene status was evaluated. RESULTS: Using the 
      clone library analysis of BALF, the phylotypes of oral streptococci and obligate 
      anaerobes were detected in 31 (79.5%) and 26 (66.7%) patients, respectively. 
      Increased oral dryness, OHI, and CPITN, but not the tongue coating score, 
      significantly correlated with higher rate of detection of obligate anaerobes, 
      although no significant associations between the detection of oral streptococci 
      in the lungs and each oral hygiene evaluation were observed. Significantly higher 
      number of obligate anaerobes were detected in the lungs in patients with total 
      oral hygiene score of >/= 5 (P = 0.008). CONCLUSION: Poor oral hygiene is 
      associated with increased obligate anaerobes in the lungs of patients with 
      pneumonia.
CI  - (c) 2019 American Academy of Periodontology.
FAU - Hata, Ryosuke
AU  - Hata R
AD  - Department of Respiratory Medicine, University of Occupational and Environmental 
      Health, Kitakyushu, Fukuoka, Japan.
FAU - Noguchi, Shingo
AU  - Noguchi S
AD  - Department of Respiratory Medicine, University of Occupational and Environmental 
      Health, Kitakyushu, Fukuoka, Japan.
FAU - Kawanami, Toshinori
AU  - Kawanami T
AD  - Department of Respiratory Medicine, University of Occupational and Environmental 
      Health, Kitakyushu, Fukuoka, Japan.
FAU - Yamasaki, Kei
AU  - Yamasaki K
AD  - Department of Respiratory Medicine, University of Occupational and Environmental 
      Health, Kitakyushu, Fukuoka, Japan.
FAU - Akata, Kentaro
AU  - Akata K
AD  - Department of Respiratory Medicine, University of Occupational and Environmental 
      Health, Kitakyushu, Fukuoka, Japan.
FAU - Ikegami, Hiroaki
AU  - Ikegami H
AD  - Department of Respiratory Medicine, University of Occupational and Environmental 
      Health, Kitakyushu, Fukuoka, Japan.
FAU - Fukuda, Kazumasa
AU  - Fukuda K
AD  - Department of Microbiology, University of Occupational and Environmental Health, 
      Kitakyushu, Fukuoka, Japan.
FAU - Hirashima, Soichi
AU  - Hirashima S
AD  - Department of Dentistry and Oral Surgery, University of Occupational and 
      Environmental Health, Kitakyushu, Fukuoka, Japan.
FAU - Miyawaki, Akihiko
AU  - Miyawaki A
AD  - Department of Dentistry and Oral Surgery, University of Occupational and 
      Environmental Health, Kitakyushu, Fukuoka, Japan.
FAU - Fujino, Yoshihisa
AU  - Fujino Y
AD  - Department of Environmental Epidemiology, Institute of Industrial Ecological 
      Sciences, University of Occupational and Environmental Health, Kitakyushu, 
      Fukuoka, Japan.
FAU - Oya, Ryoichi
AU  - Oya R
AD  - Department of Dentistry and Oral Surgery, University of Occupational and 
      Environmental Health, Kitakyushu, Fukuoka, Japan.
FAU - Yatera, Kazuhiro
AU  - Yatera K
AD  - Department of Respiratory Medicine, University of Occupational and Environmental 
      Health, Kitakyushu, Fukuoka, Japan.
FAU - Mukae, Hiroshi
AU  - Mukae H
AD  - Department of Respiratory Medicine, Unit of Translational Medicine, Nagasaki 
      University Graduate School of Biomedical Sciences, Nagasaki, Japan.
LA  - eng
PT  - Journal Article
DEP - 20191021
PL  - United States
TA  - J Periodontol
JT  - Journal of periodontology
JID - 8000345
SB  - IM
MH  - *Bacteria, Anaerobic
MH  - Bronchoalveolar Lavage Fluid
MH  - Humans
MH  - Oral Hygiene
MH  - Oral Hygiene Index
MH  - *Pneumonia
MH  - Streptococcus
OTO - NOTNLM
OT  - 16S ribosomal RNA
OT  - community periodontal index of treatment needs
OT  - hyposalivation
OT  - oral hygiene index
OT  - tongue disease
EDAT- 2019/08/01 06:00
MHDA- 2020/07/03 06:00
CRDT- 2019/08/01 06:00
PHST- 2019/01/23 00:00 [received]
PHST- 2019/05/20 00:00 [revised]
PHST- 2019/06/05 00:00 [accepted]
PHST- 2019/08/01 06:00 [pubmed]
PHST- 2020/07/03 06:00 [medline]
PHST- 2019/08/01 06:00 [entrez]
AID - 10.1002/JPER.19-0043 [doi]
PST - ppublish
SO  - J Periodontol. 2020 Jan;91(1):65-73. doi: 10.1002/JPER.19-0043. Epub 2019 Oct 21.