PMID- 31365947
OWN - NLM
STAT- MEDLINE
DCOM- 20200603
LR  - 20200603
IS  - 1438-8812 (Electronic)
IS  - 0013-726X (Linking)
VI  - 51
IP  - 9
DP  - 2019 Sep
TI  - Endoscopic ultrasound-guided liver biopsy using a 22-G fine needle biopsy needle: 
      a prospective study.
PG  - 818-824
LID - 10.1055/a-0967-3640 [doi]
AB  - BACKGROUND: Endoscopic ultrasound-guided liver biopsy (EUS-LB) using a 19-gauge 
      (19-G) EUS needle is becoming increasingly popular. We evaluated the efficacy and 
      safety of a 22-G EUS fine needle biopsy (FNB) needle for performing EUS-LB. 
      METHODS: Patients referred for evaluation of elevated liver enzymes and without 
      obstructive disease requiring endoscopic retrograde cholangiopancreatography 
      (ERCP) were included. Using a 22-G FNB needle, two passes were made from the left 
      lobe and one from the right. The main outcome measure was adequacy of the 
      specimen for histology interpretation, and the secondary outcome was the safety 
      of EUS-guided liver biopsy with a 22-G FNB needle. Patients were followed for 
      post-procedure complications for 30 days. RESULTS: 40 patients (median age 61 
      years; 26 women) underwent EUS-LB. Analyzing by needle passes, the median longest 
      core fragment was 12 mm (1st quartile - 3rd quartile 10 mm - 16.25 mm, 
      interquartile range [IQR] 6.25 mm) from the left lobe and 11 mm (10 
      mm - 15.75 mm, IQR 5.75 mm) from the right lobe. The median cumulative core 
      length per patient was 55 mm (44.5 mm - 68 mm, IQR 23.5 mm). The median 
      cumulative number of complete portal triads (CPTs) per patient was 42 (28.5 - 53, 
      IQR 24.5). The specimen was considered adequate in all 40 patients (100 %). 
      Self-limiting abdominal pain was reported in 6 patients (15 %). CONCLUSIONS: 
      EUS-LB using a 22-G FNB needle is a safe and viable alternative to the use of 
      larger gauge needles, yielding adequate tissue for evaluation of parenchymal 
      disease in 100 % of the patients.
CI  - (c) Georg Thieme Verlag KG Stuttgart . New York.
FAU - Hasan, Muhammad K
AU  - Hasan MK
AD  - Center for Interventional Endoscopy, AdventHealth Orlando, Florida, USA.
FAU - Kadkhodayan, Kambiz
AU  - Kadkhodayan K
AD  - Center for Interventional Endoscopy, AdventHealth Orlando, Florida, USA.
FAU - Idrisov, Evgeny
AU  - Idrisov E
AD  - Department of Internal Medicine, AdventHealth Orlando, Florida, USA.
FAU - Ali, Saeed
AU  - Ali S
AD  - Department of Internal Medicine, AdventHealth Orlando, Florida, USA.
FAU - Rafiq, Ehsan
AU  - Rafiq E
AD  - Department of Gastroenterology and Hepatology, AdventHealth Orlando, Florida, 
      USA.
FAU - Ben-Ami Shor, Dana
AU  - Ben-Ami Shor D
AD  - Center for Interventional Endoscopy, AdventHealth Orlando, Florida, USA.
AD  - Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
FAU - Abdel-Jalil, Ala
AU  - Abdel-Jalil A
AD  - Center for Interventional Endoscopy, AdventHealth Orlando, Florida, USA.
FAU - Navaneethan, Uday
AU  - Navaneethan U
AD  - Center for Interventional Endoscopy, AdventHealth Orlando, Florida, USA.
FAU - Bang, Ji
AU  - Bang J
AD  - Center for Interventional Endoscopy, AdventHealth Orlando, Florida, USA.
FAU - Varadarajulu, Shyam
AU  - Varadarajulu S
AD  - Center for Interventional Endoscopy, AdventHealth Orlando, Florida, USA.
FAU - Hawes, Robert
AU  - Hawes R
AD  - Center for Interventional Endoscopy, AdventHealth Orlando, Florida, USA.
FAU - Pernicone, Peter
AU  - Pernicone P
AD  - Department of Pathology, AdventHealth Orlando, Florida, USA.
LA  - eng
PT  - Journal Article
DEP - 20190731
PL  - Germany
TA  - Endoscopy
JT  - Endoscopy
JID - 0215166
SB  - IM
CIN - Endoscopy. 2019 Sep;51(9):811-812. PMID: 31461770
CIN - Endoscopy. 2019 Sep;51(9):903. PMID: 31461774
CIN - Endoscopy. 2020 Feb;52(2):157. PMID: 31991474
CIN - Endoscopy. 2020 Feb;52(2):158. PMID: 31991475
MH  - Abdominal Pain/epidemiology
MH  - Endoscopic Ultrasound-Guided Fine Needle Aspiration/adverse 
      effects/*instrumentation
MH  - Endosonography
MH  - Female
MH  - Humans
MH  - Liver Diseases/diagnostic imaging/*pathology
MH  - Male
MH  - Middle Aged
MH  - *Needles
MH  - Pain, Postoperative/epidemiology
MH  - Prospective Studies
COIS- The following authors disclosed financial relationships relevant to this 
      publication. Muhammad K. Hasan is a consultant for Boston Scientific and Olympus 
      America. Robert Hawes is a consultant for Boston Scientific, Olympus America, and 
      Medtronic. Shyam Varadarajulu is a consultant for Boston Scientific and Olympus 
      America. All other authors disclosed no financial relationships relevant to this 
      publication.
EDAT- 2019/08/01 06:00
MHDA- 2020/06/04 06:00
CRDT- 2019/08/01 06:00
PHST- 2019/08/01 06:00 [pubmed]
PHST- 2020/06/04 06:00 [medline]
PHST- 2019/08/01 06:00 [entrez]
AID - 10.1055/a-0967-3640 [doi]
PST - ppublish
SO  - Endoscopy. 2019 Sep;51(9):818-824. doi: 10.1055/a-0967-3640. Epub 2019 Jul 31.