PMID- 31366877
OWN - NLM
STAT- MEDLINE
DCOM- 20200114
LR  - 20200114
IS  - 1347-5215 (Electronic)
IS  - 0918-6158 (Linking)
VI  - 42
IP  - 8
DP  - 2019
TI  - Adverse Reaction of Dextran Sodium Sulfate-Induced Colitis in a Collagen-Induced 
      Mouse Arthritis Model.
PG  - 1419-1422
LID - 10.1248/bpb.b19-00099 [doi]
AB  - The pathogenic relationship of ulcerative colitis and rheumatoid arthritis is not 
      known. Therefore, we examined dextran sodium sulfate (DSS)-induced colitis 
      separately and in combination with a mouse arthritis model that mimics rheumatoid 
      arthritis and evaluated the deterioration-related factors of each condition. 
      Arthritis was induced in a collagen-induced arthritis mouse model using 
      DBA/1JJmsSlc mice and ulcerative colitis was induced by the administration of 
      drinking water containing 3.0% (w/v) DSS. The arthritis/DSS-treated mice 
      developed worse colitis scores compared to that of the other groups of mice. The 
      arthritis/DSS-treated mice did not demonstrate changes in hind foot volumes or in 
      the concentration of matrix metalloproteinase-3 (MMP-3) in the plasma; however, 
      plasma levels of interleukin-6 (IL-6) and tumor necrosis factor (TNF)-alpha were 
      increased. Our results showed that IL-6 and TNF-alpha may influence the deterioration 
      effect of colitis in arthritic mice.
FAU - Goto, Kenji
AU  - Goto K
AD  - Laboratory of Clinical Pharmacology, Faculty of Pharmaceutical Sciences, Suzuka 
      University of Medical Science.
AD  - Laboratory of Pathophysiology and Pharmacotherapy, Faculty of Pharmaceutical 
      Sciences, Suzuka University of Medical Science.
FAU - Hiramoto, Keiichi
AU  - Hiramoto K
AD  - Laboratory of Pathophysiology and Pharmacotherapy, Faculty of Pharmaceutical 
      Sciences, Suzuka University of Medical Science.
FAU - Ooi, Kazuya
AU  - Ooi K
AD  - Laboratory of Clinical Pharmacology, Faculty of Pharmaceutical Sciences, Suzuka 
      University of Medical Science.
AD  - Laboratory of Pathophysiology and Pharmacotherapy, Faculty of Pharmaceutical 
      Sciences, Suzuka University of Medical Science.
LA  - eng
PT  - Journal Article
PL  - Japan
TA  - Biol Pharm Bull
JT  - Biological & pharmaceutical bulletin
JID - 9311984
RN  - 0 (Interleukin-6)
RN  - 0 (Tnf protein, mouse)
RN  - 0 (Tumor Necrosis Factor-alpha)
RN  - 0 (interleukin-6, mouse)
RN  - 9042-14-2 (Dextran Sulfate)
RN  - EC 3.4.24.17 (Matrix Metalloproteinase 3)
RN  - EC 3.4.24.17 (Mmp3 protein, mouse)
SB  - IM
MH  - Animals
MH  - Arthritis, Experimental/blood/*immunology/pathology
MH  - Colitis, Ulcerative/blood/chemically induced/*immunology/pathology
MH  - Colon/pathology
MH  - Dextran Sulfate
MH  - Edema/blood/immunology/pathology
MH  - Foot/pathology
MH  - Interleukin-6/*blood
MH  - Matrix Metalloproteinase 3/blood
MH  - Mice, Inbred DBA
MH  - Tumor Necrosis Factor-alpha/*blood
OTO - NOTNLM
OT  - arthritis
OT  - interleukin-6
OT  - matrix metalloproteinase-3
OT  - tumor necrosis factor-alpha
OT  - ulcerative colitis
EDAT- 2019/08/02 06:00
MHDA- 2020/01/15 06:00
CRDT- 2019/08/02 06:00
PHST- 2019/08/02 06:00 [entrez]
PHST- 2019/08/02 06:00 [pubmed]
PHST- 2020/01/15 06:00 [medline]
AID - 10.1248/bpb.b19-00099 [doi]
PST - ppublish
SO  - Biol Pharm Bull. 2019;42(8):1419-1422. doi: 10.1248/bpb.b19-00099.