PMID- 31367236
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220409
IS  - 1758-5996 (Print)
IS  - 1758-5996 (Electronic)
IS  - 1758-5996 (Linking)
VI  - 11
DP  - 2019
TI  - Prevalence of postprandial hyperglycaemia in basal insulin-treated patients with 
      type 2 diabetes mellitus with controlled fasting glycaemia and elevated 
      glycosylated haemoglobin.
PG  - 59
LID - 10.1186/s13098-019-0452-8 [doi]
LID - 59
AB  - OBJECTIVE: To study the prevalence of postprandial hyperglycaemia (PPH) in type 2 
      diabetes mellitus (T2DM) patients treated with basal insulin, having fasting 
      glucose < 130 mg/dL but HbA1c > 7.0% (53 mmol/mol). METHODS: This was an 
      observational prospective multicentric study conducted in Spain. During 2 weeks, 
      patients recorded a 6-point self-measured blood glucose profile (before and 2 h 
      after eating) every 2 days. PPH was defined according to IDF and ADA guidelines 
      (> 160 and > 180 mg/dL, respectively). RESULTS: We included 98 patients (males: 
      56.1%; mean age: 64.3 +/- 10.4 years) who were treated with basal insulin for at 
      least 1 year at stable doses in the last 2 months, 88.8% of them received 
      concomitant oral antidiabetic drugs. Overall, 95.7% (95% CI 91.6-99.8) and 93.5% 
      (95% CI 88.6-98.5) of patients showed >/= 1 episode of PPH according to IDF and ADA 
      criteria respectively. PPH was more frequently observed after lunch and dinner. 
      The proportion of patients with >/= 40% readings in range of PPH was 59.1% (95% CI 
      49.1-69.1) and 40.9% (95% CI 30.9-50.9), according to IDF and ADA criteria, 
      respectively. CONCLUSIONS: PPH is very common and should be considered a priority 
      target in basal insulin-treated T2DM patients with elevated HbA1c despite 
      controlled fasting glucose.
FAU - Tinahones, Francisco J
AU  - Tinahones FJ
AD  - 1Hospital Universitario Virgen de la Victoria, Servicio de Endocrinologia, Campus 
      Universitario de Teatinos s/n., 29010 Malaga, Spain. ISNI: 0000 0000 9788 2492. 
      GRID: grid.411062.0
AD  - 2CIBER de Fisiopatologia de la Obesidad y Nutricion (CIBEROBN), Instituto de 
      Salud Carlos III (ISCIII), Malaga, Spain. ISNI: 0000 0000 9314 1427. GRID: 
      grid.413448.e
FAU - Molina-Vega, Maria
AU  - Molina-Vega M
AUID- ORCID: 0000-0002-0147-4369
AD  - 1Hospital Universitario Virgen de la Victoria, Servicio de Endocrinologia, Campus 
      Universitario de Teatinos s/n., 29010 Malaga, Spain. ISNI: 0000 0000 9788 2492. 
      GRID: grid.411062.0
FAU - Parra-Barona, Juan
AU  - Parra-Barona J
AD  - Hospital de Merida, Merida, Spain.
FAU - Flores-Le Roux, Juana
AU  - Flores-Le Roux J
AD  - 4Hospital del Mar, Barcelona, Spain. ISNI: 0000 0004 1767 8811. GRID: 
      grid.411142.3
FAU - Gomez-Huelgas, Ricardo
AU  - Gomez-Huelgas R
AD  - 5Hospital Universitario Regional, Servicio de Medicina Interna, FIMABIS, Malaga, 
      Spain. GRID: grid.428833.6
LA  - eng
PT  - Journal Article
DEP - 20190724
PL  - England
TA  - Diabetol Metab Syndr
JT  - Diabetology & metabolic syndrome
JID - 101488958
PMC - PMC6657157
OTO - NOTNLM
OT  - HbA1c
OT  - Hyperglycaemia
OT  - Postprandial glucose
OT  - Type 2 diabetes mellitus
COIS- Competing interestsThe authors declared that they have no competing interests.
EDAT- 2019/08/02 06:00
MHDA- 2019/08/02 06:01
PMCR- 2019/07/24
CRDT- 2019/08/02 06:00
PHST- 2019/03/12 00:00 [received]
PHST- 2019/07/03 00:00 [accepted]
PHST- 2019/08/02 06:00 [entrez]
PHST- 2019/08/02 06:00 [pubmed]
PHST- 2019/08/02 06:01 [medline]
PHST- 2019/07/24 00:00 [pmc-release]
AID - 452 [pii]
AID - 10.1186/s13098-019-0452-8 [doi]
PST - epublish
SO  - Diabetol Metab Syndr. 2019 Jul 24;11:59. doi: 10.1186/s13098-019-0452-8. 
      eCollection 2019.