PMID- 31368138
OWN - NLM
STAT- MEDLINE
DCOM- 20200210
LR  - 20221207
IS  - 1099-1751 (Electronic)
IS  - 0749-6753 (Linking)
VI  - 34
IP  - 3
DP  - 2019 Jul
TI  - Risk factors for diabetic nephropathy complications in community patients with 
      type 2 diabetes mellitus in Shanghai: Logistic regression and classification tree 
      model analysis.
PG  - 1013-1024
LID - 10.1002/hpm.2871 [doi]
AB  - BACKGROUND: The prevalence of type 2 diabetes mellitus (T2DM) in China was 11.6% 
      in 2010. Chronic complications are the main diabetes-related cause of death and 
      disability, accounting for more than 80% of the cost of diabetes treatment. 
      Diabetic nephropathy (DN) is a common microvascular complication and is the 
      second leading cause of end-stage renal failure in China. OBJECTIVE: We aimed to 
      analyse the DN status among community-based T2DM patients and to explore risk 
      factors for T2DM with DN. METHODS: This study was conducted in six communities of 
      Shanghai. We administered a questionnaire, physical examination, and biochemical 
      tests to 5078 patients with T2DM. Logistic regression and the classification tree 
      model were used to analyse risk factors for T2DM with DN. RESULTS: In total, 1937 
      patients were diagnosed with DN (prevalence 38.4%). The logistic regression model 
      indicated that course of disease more than 15 years, body mass index (BMI) 
      greater than 24 kg/m(2) , haemoglobin A1c (HbA1c) greater than 7.5%, fasting 
      blood glucose (FBG) greater than 11.0 mmol/L, total cholesterol (TC), and 
      high-density lipoprotein (HDL)-C control failure, hypertension, and diabetic 
      retinopathy were risk factors for T2DM with DN (P < .05). The classification tree 
      model identified seven risk factors (HbA1c, FBG, hypertension, postprandial blood 
      glucose, BMI, triacylglycerol, and HDL), of which, HbA1c (cut-off point 7.45%), 
      hypertension, and FBG showed the strongest association. CONCLUSION: This suggests 
      that screening for DN based on HbA1c, FBG, and hypertension should be more 
      extensively promoted by the government on a community level, more attention 
      should be focused on patients' health management, and that patients should be 
      educated on self-management.
CI  - (c) 2019 John Wiley & Sons, Ltd.
FAU - Lou, Jieqiong
AU  - Lou J
AD  - Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China.
FAU - Jing, Limei
AU  - Jing L
AD  - School of Public Health, Shanghai University of Traditional Chinese Medicine, 
      Shanghai, China.
FAU - Yang, Hui
AU  - Yang H
AD  - School of Public Health, Shanghai Jiao Tong University, Shanghai, China.
FAU - Qin, Fei
AU  - Qin F
AD  - School of Public Health, Shanghai Jiao Tong University, Shanghai, China.
FAU - Long, Wen
AU  - Long W
AD  - Department of School Hygiene, Huangpu District Center for Disease Control and 
      Prevention, Shanghai, China.
FAU - Shi, Rong
AU  - Shi R
AD  - School of Public Health, Shanghai University of Traditional Chinese Medicine, 
      Shanghai, China.
AD  - School of Public Health, Shanghai Jiao Tong University, Shanghai, China.
LA  - eng
GR  - 15GWZK1002/Shanghai Municipal Health Commission/
GR  - 15GWZK1002/Shanghai Municipal Commission/
PT  - Journal Article
DEP - 20190731
PL  - England
TA  - Int J Health Plann Manage
JT  - The International journal of health planning and management
JID - 8605825
RN  - 0 (Blood Glucose)
RN  - 0 (Glycated Hemoglobin A)
RN  - 0 (hemoglobin A1c protein, human)
RN  - 97C5T2UQ7J (Cholesterol)
MH  - Aged
MH  - Blood Glucose/analysis
MH  - Body Mass Index
MH  - China
MH  - Cholesterol/blood
MH  - Diabetes Mellitus, Type 2/*complications
MH  - Diabetic Nephropathies/epidemiology/*etiology
MH  - Diabetic Retinopathy/complications
MH  - Female
MH  - Glycated Hemoglobin/analysis
MH  - Humans
MH  - Hypertension/complications
MH  - Logistic Models
MH  - Male
MH  - Middle Aged
MH  - Risk Factors
MH  - Surveys and Questionnaires
OTO - NOTNLM
OT  - classification tree model
OT  - community patients
OT  - diabetic nephropathy
OT  - risk factors
OT  - type 2 diabetes mellitus
EDAT- 2019/08/02 06:00
MHDA- 2020/02/11 06:00
CRDT- 2019/08/02 06:00
PHST- 2019/08/02 06:00 [pubmed]
PHST- 2020/02/11 06:00 [medline]
PHST- 2019/08/02 06:00 [entrez]
AID - 10.1002/hpm.2871 [doi]
PST - ppublish
SO  - Int J Health Plann Manage. 2019 Jul;34(3):1013-1024. doi: 10.1002/hpm.2871. Epub 
      2019 Jul 31.