PMID- 31387360
OWN - NLM
STAT- MEDLINE
DCOM- 20200218
LR  - 20200218
IS  - 1940-1574 (Electronic)
IS  - 0003-3197 (Print)
IS  - 0003-3197 (Linking)
VI  - 71
IP  - 3
DP  - 2020 Mar
TI  - Applicability of Transcutaneous Oxygen Tension Measurement in the Assessment of 
      Chronic Limb-Threatening Ischemia.
PG  - 208-216
LID - 10.1177/0003319719866958 [doi]
AB  - Transcutaneous oxygen tension measurement (TcPO(2)) is widely applied for the 
      evaluation of chronic limb-threatening ischemia (CLTI). Nevertheless, studies 
      that focused on the clinical value of TcPO(2) have shown varying results. We 
      identified factors that potentially play a role in TcPO(2) measurement variation 
      such as probe placement, probe temperature, and the use of a reference probe. In 
      this review of the current literature, we assessed the application of these 
      factors. A systematic search was conducted. Parameters that were assessed were 
      probe placement, probe temperature, and mentioning and/or use of a reference 
      probe. In total, 36 articles were eligible for analysis. In 24 (67%) studies, 
      probes were placed on specific anatomical locations. Seven (19%) studies placed 
      probes, regardless of the location of the ulcer, adjacent to an ischemic lesion 
      or ulcer (perilesion). Selected temperature setting of the probe differed; in 18 
      (50%), a default probe temperature of 44 degrees C was selected, and in 13 (36%), a 
      different temperature was selected. In 31 (84%) studies, the use of a reference 
      probe was not reported. Transcutaneous oxygen tension measurement is applied 
      diversely in patients with CLTI. Homogeneity in TcPO(2) protocols is warranted 
      for reliable clinical application and to compare future TcPO(2) research.
FAU - Leenstra, Bernard
AU  - Leenstra B
AUID- ORCID: 0000-0002-2625-6472
AD  - Department of Vascular Surgery, UMC Utrecht, CX Utrecht, the Netherlands.
FAU - Wijnand, Joep
AU  - Wijnand J
AD  - Department of Vascular Surgery, UMC Utrecht, CX Utrecht, the Netherlands.
FAU - Verhoeven, Bart
AU  - Verhoeven B
AD  - Department of Vascular Surgery, Jeroen Bosch Ziekenhuis, Henri Dunantstraat, GZ 
      's-Hertogenbosch, the Netherlands.
FAU - Koning, Olivier
AU  - Koning O
AD  - Department of Vascular Surgery, Jeroen Bosch Ziekenhuis, Henri Dunantstraat, GZ 
      's-Hertogenbosch, the Netherlands.
FAU - Teraa, Martin
AU  - Teraa M
AD  - Department of Vascular Surgery, UMC Utrecht, CX Utrecht, the Netherlands.
AD  - Department of Vascular Surgery, Jeroen Bosch Ziekenhuis, Henri Dunantstraat, GZ 
      's-Hertogenbosch, the Netherlands.
AD  - Department of Nephrology and Hypertension, UMC Utrecht, Heidelberglaan, CX 
      Utrecht, the Netherlands.
FAU - Verhaar, Marianne C
AU  - Verhaar MC
AD  - Department of Nephrology and Hypertension, UMC Utrecht, Heidelberglaan, CX 
      Utrecht, the Netherlands.
FAU - de Borst, Gert J
AU  - de Borst GJ
AD  - Department of Vascular Surgery, UMC Utrecht, CX Utrecht, the Netherlands.
LA  - eng
PT  - Journal Article
DEP - 20190806
PL  - United States
TA  - Angiology
JT  - Angiology
JID - 0203706
RN  - S88TT14065 (Oxygen)
SB  - IM
MH  - Blood Gas Monitoring, Transcutaneous/methods
MH  - Chronic Disease
MH  - Humans
MH  - Ischemia/*metabolism/physiopathology
MH  - Leg/*physiopathology
MH  - Oxygen/*metabolism
MH  - Peripheral Arterial Disease/metabolism/physiopathology
MH  - Peripheral Vascular Diseases/*metabolism/physiopathology
MH  - Temperature
PMC - PMC6987479
OTO - NOTNLM
OT  - TcPO2
OT  - chronic limb-threatening ischemia
OT  - critical limb ischemia
OT  - diabetes
OT  - diabetic foot ischemia
OT  - peripheral arterial disease
OT  - transcutaneous oximetry
COIS- Declaration of Conflicting Interests: The author(s) declared no potential 
      conflicts of interest with respect to the research, authorship, and/or 
      publication of this article.
EDAT- 2019/08/08 06:00
MHDA- 2020/02/19 06:00
PMCR- 2020/01/29
CRDT- 2019/08/08 06:00
PHST- 2019/08/08 06:00 [pubmed]
PHST- 2020/02/19 06:00 [medline]
PHST- 2019/08/08 06:00 [entrez]
PHST- 2020/01/29 00:00 [pmc-release]
AID - 10.1177_0003319719866958 [pii]
AID - 10.1177/0003319719866958 [doi]
PST - ppublish
SO  - Angiology. 2020 Mar;71(3):208-216. doi: 10.1177/0003319719866958. Epub 2019 Aug 
      6.