PMID- 31387822 OWN - NLM STAT- MEDLINE DCOM- 20201130 LR - 20201130 IS - 1874-1754 (Electronic) IS - 0167-5273 (Linking) VI - 300 DP - 2020 Feb 1 TI - Impact of telephone follow-up and 24/7 hotline on 30-day readmission rates following aortic valve replacement -A randomized controlled trial. PG - 66-72 LID - S0167-5273(18)36036-4 [pii] LID - 10.1016/j.ijcard.2019.07.087 [doi] AB - BACKGROUND: Thirty-day all-cause readmissions are high after aortic valve replacement (AVR). We aimed to assess the effectiveness of a structured telephone follow-up (TFU) and a 24/7 hotline on reducing 30-day all-cause readmission (30-DACR) after AVR, on reducing symptoms of anxiety and depression and on improving perceived health state. METHODS: A prospective randomized controlled trial was conducted. Patients (n = 288) were randomly allocated to either post-discharge usual care or to care that provided TFU and access to a 24/7 hotline after AVR. Ancillary endpoints were time-to-event (readmission), proportion of avoidable versus unavoidable readmissions after AVR, and predictors of 30-DACR after AVR. RESULTS: 30-DACR was 22.3%. The structured TFU and 24/7 hotline intervention failed to reduce 30-DACR rates after AVR (P = 0.274). Symptoms of anxiety were significantly reduced 30 days after surgery (P = 0.031), an effect that did not persist one year after surgery (P = 0.108). Most readmissions occurred before 15 days post-discharge, and 75% of them were deemed to be unavoidable. Pleural drainage before hospital discharge (P = 0.027) and symptoms of anxiety before surgery (P = 0.003) were predictors of 30-DACR after AVR. CONCLUSION: The TFU and 24/7 hotline had no effect on reducing 30-DACR after AVR. However, we did measure reduced symptoms of anxiety the first month after AVR. Anxiety reduction appeared to be an important target for intervention, because we found it to be a risk factor for readmission. Future research should focus on the effectiveness of interventions to prevent avoidable unplanned readmissions. TRIAL REGISTRATION: ClinicalTrial.gov, NCT02522663. CI - Copyright (c) 2019 Elsevier B.V. All rights reserved. FAU - Danielsen, Stein Ove AU - Danielsen SO AD - Center for Patient-centered Heart and Lung Research, Department of Cardiothoracic Surgery, Division of Cardiovascular and Pulmonary Diseases, Oslo University Hospital, Ulleval, Oslo, Norway; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway; KU Leuven Department of Public Health and Primary Care, KU Leuven-University of Leuven, Leuven, Belgium. Electronic address: steinda@uio.no. FAU - Moons, Philip AU - Moons P AD - KU Leuven Department of Public Health and Primary Care, KU Leuven-University of Leuven, Leuven, Belgium; Institute of Health and Care Sciences, University of Gothenburg, Gothenburg, Sweden; Department of Paediatrics and Child Health, University of Cape Town, South Africa. FAU - Sandvik, Leiv AU - Sandvik L AD - Oslo Centre of Biostatistics and Epidemiology, Oslo University Hospital, Oslo, Norway. FAU - Leegaard, Marit AU - Leegaard M AD - Department of Nursing and Health Promotion, Faculty of Health Sciences, Oslo Metropolitan University, Oslo, Norway. FAU - Solheim, Svein AU - Solheim S AD - Center for Clinical Heart Research, Department of Cardiology, Division of Medicine, Oslo University Hospital, Ulleval, Oslo, Norway. FAU - Tonnessen, Theis AU - Tonnessen T AD - Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway; Department of Cardiothoracic Surgery, Division of Cardiovascular and Pulmonary Diseases, Oslo University Hospital, Ulleval, Oslo, Norway. FAU - Lie, Irene AU - Lie I AD - Center for Patient-centered Heart and Lung Research, Department of Cardiothoracic Surgery, Division of Cardiovascular and Pulmonary Diseases, Oslo University Hospital, Ulleval, Oslo, Norway. LA - eng SI - ClinicalTrials.gov/NCT02522663 PT - Journal Article PT - Randomized Controlled Trial DEP - 20190730 PL - Netherlands TA - Int J Cardiol JT - International journal of cardiology JID - 8200291 SB - IM MH - Aftercare MH - Aged MH - Anxiety/epidemiology/*psychology/*therapy MH - Female MH - Follow-Up Studies MH - Heart Valve Prosthesis Implantation/*psychology/*trends MH - Hotlines/methods/*trends MH - Humans MH - Male MH - Middle Aged MH - Patient Discharge/trends MH - Patient Readmission/*trends MH - Prospective Studies MH - Telephone OTO - NOTNLM OT - 30-day readmission OT - Aortic valve replacement OT - Aortic valve stenosis OT - Hotline OT - Telephone follow-up EDAT- 2019/08/08 06:00 MHDA- 2020/12/01 06:00 CRDT- 2019/08/08 06:00 PHST- 2019/02/12 00:00 [received] PHST- 2019/07/11 00:00 [revised] PHST- 2019/07/29 00:00 [accepted] PHST- 2019/08/08 06:00 [pubmed] PHST- 2020/12/01 06:00 [medline] PHST- 2019/08/08 06:00 [entrez] AID - S0167-5273(18)36036-4 [pii] AID - 10.1016/j.ijcard.2019.07.087 [doi] PST - ppublish SO - Int J Cardiol. 2020 Feb 1;300:66-72. doi: 10.1016/j.ijcard.2019.07.087. Epub 2019 Jul 30.