PMID- 31392477
OWN - NLM
STAT- MEDLINE
DCOM- 20200324
LR  - 20211020
IS  - 1432-1084 (Electronic)
IS  - 0938-7994 (Print)
IS  - 0938-7994 (Linking)
VI  - 30
IP  - 1
DP  - 2020 Jan
TI  - Mitral annular plane systolic excursion by cardiac MR is an easy tool for 
      optimized prognosis assessment in ST-elevation myocardial infarction.
PG  - 620-629
LID - 10.1007/s00330-019-06393-4 [doi]
AB  - OBJECTIVES: The purpose of this study was to assess the comparative prognostic 
      value of mitral annular plane systolic excursion (MAPSE) versus left ventricular 
      ejection fraction (LVEF), measured by cardiac magnetic resonance (CMR) imaging in 
      patients with ST-elevation myocardial infarction (STEMI) treated with primary 
      percutaneous coronary intervention (pPCI). METHODS: CMR was performed in 255 
      STEMI patients within 2 days (interquartile range (IQR) 2-4 days) after 
      infarction. CMR included MAPSE measurement on CINE 4-chamber view. Patients were 
      followed for major adverse cardiovascular events (MACE)-death, non-fatal 
      myocardial re-infarction, stroke, and new congestive heart failure. RESULTS: 
      Patients with MACE (n = 35, 14%, median follow-up 3 years [IQR 1-4 years]) showed 
      significantly lower MAPSE (8 mm [7-8.8] vs. 9.6 mm [8.1-11.5], p < 0.001). The 
      association between decreased MAPSE (< 9 mm, optimal cut-off value by 
      c-statistics) remained significant after adjustment for independent clinical and 
      CMR predictors of MACE. The AUC of MAPSE for the prediction of MACE was 0.74 (CI 
      95% 0.65-0.82), significantly higher than that of LVEF (0.61 [CI 95% 0.50-0.71]; 
      p < 0.001). CONCLUSIONS: Reduced long-axis function assessed with MAPSE 
      measurement using CINE CMR independently predicts long-term prognosis following 
      STEMI. Moreover, MAPSE provided significantly higher prognostic implication in 
      comparison with conventional LVEF measurement. KEY POINTS: * MAPSE determined by 
      CMR independently predicts long-term prognosis following STEMI. * MACE-free 
      survival is significantly higher in patients with MAPSE >/= 9 mm than < 9 mm. * 
      MAPSE provides significantly higher prognostic implication than conventional 
      LVEF.
FAU - Mayr, Agnes
AU  - Mayr A
AD  - University Clinic of Radiology, Medical University Innsbruck, Anichstrasse 35, 
      A-6020, Innsbruck, Austria. agnes.mayr@tirol-kliniken.at.
FAU - Pamminger, Mathias
AU  - Pamminger M
AD  - University Clinic of Radiology, Medical University Innsbruck, Anichstrasse 35, 
      A-6020, Innsbruck, Austria.
FAU - Reindl, Martin
AU  - Reindl M
AD  - University Clinic of Internal Medicine III, Cardiology and Angiology, Medical 
      University Innsbruck, Anichstrasse 35, A-6020, Innsbruck, Austria.
FAU - Greulich, Simon
AU  - Greulich S
AD  - Department of Cardiology and Cardiovascular Diseases, University Hospital 
      Tubingen, Otfried Muller-Strasse 10, 72076, Tubingen, Germany.
FAU - Reinstadler, Sebastian J
AU  - Reinstadler SJ
AD  - University Clinic of Internal Medicine III, Cardiology and Angiology, Medical 
      University Innsbruck, Anichstrasse 35, A-6020, Innsbruck, Austria.
FAU - Tiller, Christina
AU  - Tiller C
AD  - University Clinic of Internal Medicine III, Cardiology and Angiology, Medical 
      University Innsbruck, Anichstrasse 35, A-6020, Innsbruck, Austria.
FAU - Holzknecht, Magdalena
AU  - Holzknecht M
AD  - University Clinic of Internal Medicine III, Cardiology and Angiology, Medical 
      University Innsbruck, Anichstrasse 35, A-6020, Innsbruck, Austria.
FAU - Nalbach, Timo
AU  - Nalbach T
AD  - University Clinic of Radiology, Medical University Innsbruck, Anichstrasse 35, 
      A-6020, Innsbruck, Austria.
FAU - Plappert, David
AU  - Plappert D
AD  - University Clinic of Radiology, Medical University Innsbruck, Anichstrasse 35, 
      A-6020, Innsbruck, Austria.
FAU - Kranewitter, Christof
AU  - Kranewitter C
AD  - University Clinic of Radiology, Medical University Innsbruck, Anichstrasse 35, 
      A-6020, Innsbruck, Austria.
FAU - Klug, Gert
AU  - Klug G
AD  - University Clinic of Internal Medicine III, Cardiology and Angiology, Medical 
      University Innsbruck, Anichstrasse 35, A-6020, Innsbruck, Austria.
FAU - Metzler, Bernhard
AU  - Metzler B
AD  - University Clinic of Internal Medicine III, Cardiology and Angiology, Medical 
      University Innsbruck, Anichstrasse 35, A-6020, Innsbruck, Austria.
LA  - eng
PT  - Journal Article
PT  - Observational Study
DEP - 20190807
PL  - Germany
TA  - Eur Radiol
JT  - European radiology
JID - 9114774
SB  - IM
MH  - Female
MH  - Heart Ventricles/diagnostic imaging/physiopathology
MH  - Humans
MH  - Magnetic Resonance Imaging/*methods
MH  - Male
MH  - Middle Aged
MH  - Prognosis
MH  - Prospective Studies
MH  - ST Elevation Myocardial Infarction/complications/*diagnostic 
      imaging/*physiopathology
MH  - Stroke Volume
MH  - Ventricular Dysfunction, Left/complications/*diagnostic imaging/*physiopathology
PMC - PMC6890588
OTO - NOTNLM
OT  - Magnetic resonance imaging
OT  - Prognosis
OT  - ST-elevation myocardial infarction
COIS- The authors of this manuscript declare no relationships with any companies whose 
      products or services may be related to the subject matter of the article.
EDAT- 2019/08/09 06:00
MHDA- 2020/03/25 06:00
PMCR- 2019/08/07
CRDT- 2019/08/09 06:00
PHST- 2019/03/29 00:00 [received]
PHST- 2019/07/24 00:00 [accepted]
PHST- 2019/07/16 00:00 [revised]
PHST- 2019/08/09 06:00 [pubmed]
PHST- 2020/03/25 06:00 [medline]
PHST- 2019/08/09 06:00 [entrez]
PHST- 2019/08/07 00:00 [pmc-release]
AID - 10.1007/s00330-019-06393-4 [pii]
AID - 6393 [pii]
AID - 10.1007/s00330-019-06393-4 [doi]
PST - ppublish
SO  - Eur Radiol. 2020 Jan;30(1):620-629. doi: 10.1007/s00330-019-06393-4. Epub 2019 
      Aug 7.