PMID- 31400999
OWN - NLM
STAT- MEDLINE
DCOM- 20191125
LR  - 20191125
IS  - 1532-2653 (Electronic)
IS  - 0967-5868 (Linking)
VI  - 68
DP  - 2019 Oct
TI  - Intrathecal baclofen trial using a temporary indwelling intrathecal catheter - A 
      single institution experience.
PG  - 33-38
LID - S0967-5868(19)30415-1 [pii]
LID - 10.1016/j.jocn.2019.07.073 [doi]
AB  - Intrathecal baclofen infusion trial is a sophisticated tool for selecting 
      patients for permanent intra thecal baclofen infusion therapy We report our 
      clinical experience of fifteen patients with refractory spasticity who underwent 
      a continuous ITB trial using a temporary intraspinal indwelling catheter prior to 
      permanent pump implantation. Patients underwent placement of a temporary 
      intrathecal catheter that was connected to an external pump. Multisource feedback 
      was obtained from the various healthcare professionals involved (Staff Nurse, 
      Specialist nurse, physiotherapist, Doctor, family members, patient) regarding 
      progress of test over 48-72 h. Average Modified Ashworth score after the trial 
      was less than 2. Some degree of dose related minor adverse events (AEs) occurred 
      in 8 patients, with the most common being nausea, constipation, urinary retention 
      and hypotension. 10 patients received pump implant. 5 patients did not receive a 
      pump because of AEs or because the goals were not met. 1 patient had pump removed 
      after 4 years because of infection.
CI  - Crown Copyright (c) 2019. Published by Elsevier Ltd. All rights reserved.
FAU - Vats, Atul
AU  - Vats A
AD  - James Cook University Hospital, Middlesbrough TS43BW, UK. Electronic address: 
      vatsatul7@gmail.com.
FAU - Amit, Amit
AU  - Amit A
AD  - University Hospital Coventry and Warwickshire, Coventry CV22DX, UK. Electronic 
      address: amit.amit@uhcw.nhs.uk.
FAU - Cossar, Martin
AU  - Cossar M
AD  - Aberdeen Royal Infirmary, Foresterhill Health Campus, Foresterhill Rd, Aberdeen 
      AB25 2ZN, UK. Electronic address: martin.cossar@nhs.net.
FAU - Bhatt, Pragnesh
AU  - Bhatt P
AD  - Aberdeen Royal Infirmary, Foresterhill Health Campus, Foresterhill Rd, Aberdeen 
      AB25 2ZN, UK. Electronic address: pragnesh.bhatt@nhs.net.
FAU - Cozens, Alastair
AU  - Cozens A
AD  - Aberdeen Royal Infirmary, Foresterhill Health Campus, Foresterhill Rd, Aberdeen 
      AB25 2ZN, UK. Electronic address: alastair.cozens@nhs.net.
LA  - eng
PT  - Journal Article
DEP - 20190807
PL  - Scotland
TA  - J Clin Neurosci
JT  - Journal of clinical neuroscience : official journal of the Neurosurgical Society 
      of Australasia
JID - 9433352
RN  - 0 (Muscle Relaxants, Central)
RN  - H789N3FKE8 (Baclofen)
SB  - IM
MH  - Aged
MH  - Baclofen/*administration & dosage/adverse effects
MH  - Catheters, Indwelling
MH  - Female
MH  - Humans
MH  - Infusion Pumps, Implantable
MH  - Injections, Spinal
MH  - Male
MH  - Middle Aged
MH  - Muscle Relaxants, Central/*administration & dosage/adverse effects
MH  - Muscle Spasticity/*drug therapy
MH  - *Patient Selection
MH  - Retrospective Studies
OTO - NOTNLM
OT  - Baclofen pump
OT  - Intrathecal baclofen
OT  - Intrathecal catheter
EDAT- 2019/08/12 06:00
MHDA- 2019/11/26 06:00
CRDT- 2019/08/12 06:00
PHST- 2019/02/27 00:00 [received]
PHST- 2019/06/16 00:00 [revised]
PHST- 2019/07/29 00:00 [accepted]
PHST- 2019/08/12 06:00 [pubmed]
PHST- 2019/11/26 06:00 [medline]
PHST- 2019/08/12 06:00 [entrez]
AID - S0967-5868(19)30415-1 [pii]
AID - 10.1016/j.jocn.2019.07.073 [doi]
PST - ppublish
SO  - J Clin Neurosci. 2019 Oct;68:33-38. doi: 10.1016/j.jocn.2019.07.073. Epub 2019 
      Aug 7.