PMID- 31402972
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20200930
IS  - 2039-4330 (Print)
IS  - 2039-4349 (Electronic)
IS  - 2039-4330 (Linking)
VI  - 9
IP  - 1
DP  - 2019 May 6
TI  - Assessment of cochlear trauma and telemetry measures after cochlear implantation: 
      A comparative study between Nucleus((R)) CI512 and CI532 electrode arrays.
PG  - 223
LID - 10.4081/audiores.2019.223 [doi]
LID - 223
AB  - The aim of this study was to compare the new Cochlear() Nucleus((R)) Profile with 
      Slim Modiolar Electrode (CI532, Cochlear Ltd., Sidney, Australia) with the 
      previous Contour Advance((R)) (CI512) implant through postoperative residual 
      hearing (RH) threshold shift and telemetry measurements as indirect measures of 
      cochlear trauma. We compared 21 patients implanted with the CI532 and 20 patients 
      implanted with the CI512, matching the 2 groups for age and for hearing loss 
      etiology. All subjects received audiological pure tone average (PTA) calculation 
      pre- and postimplant. Electrode impedance was measured, followed by AutoNRT((R)) to 
      measure and evaluate the Neural Response Telemetry (NRT((R))) thresholds. Telemetry 
      recordings were made intraoperatively, one month after surgery and one month 
      after activation. The NRT-Ratio was calculated to evaluate full scala tympani 
      (ST) insertion. The results showed a higher number of patients with preserved 
      measurable hearing with the CI532 (10/15; P>0.05) compared to the CI512 (5/14; 
      P<0.05). A significant difference in post-operative low frequency PTA was 
      observed between the two groups. There were no significant differences for 
      telemetry measurements and NRTRatio evaluation of full ST insertion (CI512: 81%; 
      CI532: 95%). A significantly higher number of patients who preserved measurable 
      hearing with the CI532, and a significantly higher post-operative low frequency 
      PTA threshold compared with the CI512 confirmed better RH preservation and lower 
      apical cochlear damage with the CI532. There was a high number of full ST 
      insertions for both electrode arrays. Future studies should investigate the 
      audiological effect of implantation in patients with higher levels of RH, 
      correlating the results with the scalar position, to assess any lesser trauma of 
      the CI532.
FAU - Cuda, Domenico
AU  - Cuda D
AD  - Department of Otorhinolaryngology, Guglielmo da Saliceto Hospital, Piacenza, 
      Italy.
FAU - Murri, Alessandra
AU  - Murri A
AD  - Department of Otorhinolaryngology, Guglielmo da Saliceto Hospital, Piacenza, 
      Italy.
LA  - eng
PT  - Journal Article
DEP - 20190711
PL  - Switzerland
TA  - Audiol Res
JT  - Audiology research
JID - 101644681
PMC - PMC6646859
OTO - NOTNLM
OT  - Cochlear implant
OT  - Cochlear trauma
OT  - Electrode array
COIS- Conflict of interest and funding: Cochlear Ltd. supports the authors for the 
      statystical analysis.
EDAT- 2019/08/14 06:00
MHDA- 2019/08/14 06:01
PMCR- 2019/07/11
CRDT- 2019/08/13 06:00
PHST- 2019/03/31 00:00 [received]
PHST- 2019/06/08 00:00 [accepted]
PHST- 2019/08/13 06:00 [entrez]
PHST- 2019/08/14 06:00 [pubmed]
PHST- 2019/08/14 06:01 [medline]
PHST- 2019/07/11 00:00 [pmc-release]
AID - 10.4081/audiores.2019.223 [doi]
PST - epublish
SO  - Audiol Res. 2019 Jul 11;9(1):223. doi: 10.4081/audiores.2019.223. eCollection 
      2019 May 6.