PMID- 31404223
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20201001
IS  - 2146-4618 (Print)
IS  - 2146-4626 (Electronic)
IS  - 2146-4626 (Linking)
VI  - 8
IP  - 3
DP  - 2019 Sep
TI  - Dexmedetomidine to Treat 3, 4-Methylenedioxymethamphetamine-Induced Agitation in 
      a 13-Month-Old Infant: A Case Report and Literature Review.
PG  - 175-177
LID - 10.1055/s-0039-1677815 [doi]
AB  - We report a 13-month-old infant who accidentally ingested a tablet of 3, 
      4-methylenedioxymethamphetamine (MDMA) and was brought to the emergency 
      department with tachycardia, seizures, mydriasis, and altered mental status. The 
      patient received multiple doses of benzodiazepines to treat the seizures and 
      developed respiratory insufficiency needing intubation. After extubation, the 
      patient developed hyperactivity, myoclonic, and choreoathetoid movements which 
      were unresponsive to benzodiazepines. Dexmedetomidine was started with good 
      response. The patient made a full clinical recovery. This is the first case that 
      illustrates the possibility to treat MDMA-induced agitation with dexmedetomidine 
      in a 13-month-old infant.
FAU - Sanders, Patricia J L T
AU  - Sanders PJLT
AD  - Section of Pediatric Intensive Care, Department of Pediatrics, Maastricht 
      University Medical Center (MUMC + ), Maastricht, The Netherlands.
FAU - Hanot, Jan
AU  - Hanot J
AD  - Section of Pediatric Intensive Care, Department of Pediatrics, Maastricht 
      University Medical Center (MUMC + ), Maastricht, The Netherlands.
LA  - eng
PT  - Case Reports
DEP - 20190213
PL  - Germany
TA  - J Pediatr Intensive Care
JT  - Journal of pediatric intensive care
JID - 101592756
PMC - PMC6687446
OTO - NOTNLM
OT  - MDMA
OT  - dexmedetomidine
OT  - infant
COIS- Conflict of Interest None declared.
EDAT- 2019/08/14 06:00
MHDA- 2019/08/14 06:01
PMCR- 2020/09/01
CRDT- 2019/08/13 06:00
PHST- 2018/10/04 00:00 [received]
PHST- 2019/01/01 00:00 [accepted]
PHST- 2019/08/13 06:00 [entrez]
PHST- 2019/08/14 06:00 [pubmed]
PHST- 2019/08/14 06:01 [medline]
PHST- 2020/09/01 00:00 [pmc-release]
AID - 1800043 [pii]
AID - 10.1055/s-0039-1677815 [doi]
PST - ppublish
SO  - J Pediatr Intensive Care. 2019 Sep;8(3):175-177. doi: 10.1055/s-0039-1677815. 
      Epub 2019 Feb 13.