PMID- 31415780
OWN - NLM
STAT- MEDLINE
DCOM- 20200115
LR  - 20200115
IS  - 1527-9995 (Electronic)
IS  - 0090-4295 (Linking)
VI  - 133
DP  - 2019 Nov
TI  - The Minimum Clinically Important Difference of the International Consultation on 
      Incontinence Questionnaires (ICIQ-UI SF and ICIQ-LUTSqol).
PG  - 91-95
LID - S0090-4295(19)30712-5 [pii]
LID - 10.1016/j.urology.2019.08.004 [doi]
AB  - OBJECTIVE: To estimate the minimum clinically important difference (MCID) of the 
      International Consultation on Incontinence Questionnaire-Urinary Incontinence 
      Short Form (ICIQ-UI SF) and the International Consultation on Incontinence 
      Questionnaire-Lower Urinary Tract Symptoms Quality of Life (ICIQ-LUTSqol) using 
      both anchor-based and distribution-based methods for women with stress urinary 
      incontinence undergoing nonsurgical treatment. MATERIALS AND METHODS: Data from a 
      randomized clinical trial evaluating efficacy of a nonsurgical intervention in 
      women with stress urinary incontinence were used for analyses. The overall score 
      of ICIQ-UI SF ranges from 0 to 21, with greater values indicating increased 
      severity. The ICIQ-LUTSqol ranges from 19 to 76, with greater values indicating 
      increased impact on quality of life. Instruments used in the anchor-based method 
      were the Patient Global Impression of Improvement, patient satisfaction, 1-hour 
      pad test and the incontinence episode frequency. The distribution-based method 
      used an effect size of 0.5 standard deviation. Triangulation of findings was used 
      to converge on a single value of MCID. RESULTS: At 12-month post-treatment, 106 
      (88.3%) participants completed the follow-up and were included in the analysis. 
      Anchor-based MCIDs of the ICIQ-UI SF were between 3.4 and 4.4, while the 
      distribution-based MCID was 1.7. Anchor-based MCIDs of the ICIQ-LUTSqol were 
      between 4.8 and 6.9, while the distribution-based MCID was 5.2. Triangulation of 
      findings showed that MCIDs of 4 for ICIQ-UI SF and 6 for ICIQ-LUTSqol were the 
      most appropriate. CONCLUSION: For women undergoing nonsurgical treatments for 
      incontinence, reductions of 4 and 6 points in ICIQ-UI SF and ICIQ-LUTSqol, 
      respectively are perceived as clinically meaningful.
CI  - Copyright (c) 2019 Elsevier Inc. All rights reserved.
FAU - Lim, Renly
AU  - Lim R
AD  - School of Pharmaceutical Sciences, Universiti Sains Malaysia, Penang, Malaysia; 
      Quality Use of Medicines and Pharmacy Research Centre, School of Pharmacy and 
      Medical Sciences, University of South Australia, Adelaide, Australia. Electronic 
      address: renly_lim@hotmail.com.
FAU - Liong, Men Long
AU  - Liong ML
AD  - Department of Urology, Island Hospital, Penang, Malaysia.
FAU - Lim, Ka Keat
AU  - Lim KK
AD  - Programme in Health Services and Systems Research, Duke University-National 
      University of Singapore (Duke-NUS) Medical School, Singapore.
FAU - Leong, Wing Seng
AU  - Leong WS
AD  - Department of Urology, Lam Wah Ee Hospital, Penang, Malaysia.
FAU - Yuen, Kah Hay
AU  - Yuen KH
AD  - School of Pharmaceutical Sciences, Universiti Sains Malaysia, Penang, Malaysia.
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Randomized Controlled Trial
DEP - 20190812
PL  - United States
TA  - Urology
JT  - Urology
JID - 0366151
SB  - IM
MH  - *Diagnostic Self Evaluation
MH  - Female
MH  - Humans
MH  - Lower Urinary Tract Symptoms/diagnosis
MH  - Middle Aged
MH  - *Quality of Life
MH  - *Self Report
MH  - Severity of Illness Index
MH  - Urinary Incontinence, Stress/*diagnosis/*therapy
EDAT- 2019/08/16 06:00
MHDA- 2020/01/16 06:00
CRDT- 2019/08/16 06:00
PHST- 2019/05/09 00:00 [received]
PHST- 2019/07/31 00:00 [revised]
PHST- 2019/08/05 00:00 [accepted]
PHST- 2019/08/16 06:00 [pubmed]
PHST- 2020/01/16 06:00 [medline]
PHST- 2019/08/16 06:00 [entrez]
AID - S0090-4295(19)30712-5 [pii]
AID - 10.1016/j.urology.2019.08.004 [doi]
PST - ppublish
SO  - Urology. 2019 Nov;133:91-95. doi: 10.1016/j.urology.2019.08.004. Epub 2019 Aug 
      12.