PMID- 31416046 OWN - NLM STAT- MEDLINE DCOM- 20200323 LR - 20200323 IS - 1557-2501 (Electronic) IS - 1042-3931 (Linking) VI - 31 IP - 10 DP - 2019 Oct TI - Feasibility of Transfemoral Aortic Valve Implantation in Patients With Aortic Disease and Simultaneous or Sequential Endovascular Aortic Repair. PG - 289-295 LID - JIC2019815-2 [pii] AB - OBJECTIVES: The transfemoral approach for transcatheter aortic valve implantation (TF-TAVI) is associated with a significant survival benefit for intermediate and high-risk patients. Due to the increased procedural risk, many operators avoid TF-TAVI in patients with aortic disease. Moreover, significant peri-interventional device interaction may occur in patients with previous endovascular aortic repair (EVAR). We evaluated the feasibility of TF-TAVI in patients with aortic disease in combination with simultaneous or sequential EVAR. METHODS: Data from 15 TF-TAVI patients with concomitant aortic disease treated between 2009 and 2019 in three German heart centers representing 4410 TAVI procedures were analyzed. RESULTS: Two patients with progressive penetrating atherosclerotic ulcers (PAUs) in the descending thoracic aorta underwent sequential and simultaneous thoracic EVAR (TEVAR), respectively. One patient with stable PAU and 4 patients with not yet relevant abdominal aortic aneurysm (AAA) underwent isolated TF-TAVI. One patient with relevant AAA underwent TF-TAVI and sequential EVAR. Seven patients with previous EVAR due to an AAA underwent TF-TAVI (5 with a bifurcated graft and 2 with a straight graft). TF-TAVI and sequential or simultaneous TEVAR were technically successful in all patients. Vascular complications occurred in 1 patient. One patient died within 30 days and 2 patients died within 12 months. CONCLUSION: TF-TAVI can be performed successfully in patients with aortic disease or previous endovascular aortoiliac intervention. Simultaneous and sequential (T)EVAR is feasible. FAU - Patsalis, Polykarpos C AU - Patsalis PC AD - Heart Center Bergmannsheil, Department of Cardiology and Angiology, Ruhr University Bochum, Burkle-de-la-Camp-Platz 1, 44789 Bochum, Germany. polykarpos.patsalis@bergmannsheil.de. FAU - Alotaibi, Sultan AU - Alotaibi S FAU - Wolf, Alexander AU - Wolf A FAU - Scholtz, Werner AU - Scholtz W FAU - Kloppe, Axel AU - Kloppe A FAU - Plicht, Bjorn AU - Plicht B FAU - Buck, Thomas AU - Buck T FAU - Haldenwang, Peter Lukas AU - Haldenwang PL FAU - Strauch, Justus Thomas AU - Strauch JT FAU - Nicolas, Volkmar AU - Nicolas V FAU - Rudolph, Volker AU - Rudolph V FAU - Mugge, Andreas AU - Mugge A FAU - Naber, Christoph K AU - Naber CK LA - eng PT - Journal Article PT - Multicenter Study DEP - 20190815 PL - United States TA - J Invasive Cardiol JT - The Journal of invasive cardiology JID - 8917477 SB - IM MH - Aged MH - Aged, 80 and over MH - *Aorta, Thoracic MH - Aortic Diseases/*complications/diagnosis/*surgery MH - Aortic Valve Stenosis/complications/diagnosis/*surgery MH - Endovascular Procedures/*methods MH - Feasibility Studies MH - Female MH - Femoral Artery MH - Follow-Up Studies MH - Germany/epidemiology MH - Humans MH - Incidence MH - Male MH - Postoperative Complications/epidemiology MH - Retrospective Studies MH - Survival Rate/trends MH - Tomography, X-Ray Computed MH - Transcatheter Aortic Valve Replacement/*methods OTO - NOTNLM OT - aortic disease OT - aortic valve stenosis OT - percutaneous intervention EDAT- 2019/08/16 06:00 MHDA- 2020/03/24 06:00 CRDT- 2019/08/16 06:00 PHST- 2019/08/16 06:00 [pubmed] PHST- 2020/03/24 06:00 [medline] PHST- 2019/08/16 06:00 [entrez] AID - JIC2019815-2 [pii] PST - ppublish SO - J Invasive Cardiol. 2019 Oct;31(10):289-295. Epub 2019 Aug 15.