PMID- 31420200
OWN - NLM
STAT- MEDLINE
DCOM- 20201005
LR  - 20201005
IS  - 1573-2509 (Electronic)
IS  - 0920-9964 (Linking)
VI  - 212
DP  - 2019 Oct
TI  - Basic self-disturbances independently predict recovery in psychotic disorders: A 
      seven year follow-up study.
PG  - 72-78
LID - S0920-9964(19)30350-0 [pii]
LID - 10.1016/j.schres.2019.08.009 [doi]
AB  - BACKGROUND: Recovery is the ultimate goal of psychosis treatment. Basic 
      self-disturbances (BSDs) are non-psychotic phenomena associated with clinical 
      outcome, present in prodromal, psychotic and residual phases of psychotic 
      disorders. AIM: To investigate the relationship between BSDs and recovery seven 
      years after first treatment in patients with psychotic disorders. METHOD: 
      Prospective longitudinal study of 56 patients recruited during first adequate 
      treatment for schizophrenia (n = 35) and other psychotic disorders (n = 21) 
      (psychotic bipolar disorder, delusional disorder, psychotic disorder NOS). At 
      baseline and follow-up BSDs were assessed using the Examination of Anomalous 
      Self-Experience (EASE) manual, while standard clinical instruments were used to 
      ascertained diagnosis, clinical symptom severity, and functioning. Recovery was 
      defined as absence of psychotic symptoms and regaining of functioning that 
      persisted the last two years before follow-up. RESULTS: At follow up, 34% 
      achieved recovery (5 (14%) with schizophrenia and 14 (67%) with other psychoses 
      at baseline). Recovery was predicted by an absence of a schizophrenia diagnosis, 
      low baseline level of BSDs and further reductions in BSDs from baseline to 
      follow-up. Change in BSDs was the strongest predictor, also after adjusting for 
      premorbid adjustment and duration of untreated psychosis, and was not confounded 
      by diagnosis. CONCLUSION: Low baseline levels of basic self-disturbances and 
      further reductions over time independently predict recovery seven years later in 
      first treated psychosis patients.
CI  - Copyright (c) 2019 Elsevier B.V. All rights reserved.
FAU - Svendsen, Ingrid Hartveit
AU  - Svendsen IH
AD  - Innlandet Hospital Trust, Department of Acute Psychiatry and Psychosis Treatment, 
      Presteseter 1, 2840 Reinsvoll, Norway; University of Oslo, Faculty of Medicine, 
      P. B. 1018 Blindern, 0315 Oslo, Norway. Electronic address: 
      ingridhartveit.svendsen@sykehuset-innlandet.no.
FAU - Oie, Merete G
AU  - Oie MG
AD  - Department of Psychology, University of Oslo, Pb 1094 Blindern, Norway; Division 
      of Research, Innlandet Hospital Trust, Norway. Electronic address: 
      m.g.oie@psykologi.uio.no.
FAU - Moller, Paul
AU  - Moller P
AD  - Vestre Viken Hospital Trust, Division of Mental Health and Addiction, Department 
      of Mental Health Research and Development, Norway. Electronic address: 
      Paul.Moller@vestreviken.no.
FAU - Nelson, Barnaby
AU  - Nelson B
AD  - Orygen, The National Centre of Excellence in Youth Mental Health, Centre for 
      Youth Mental Health, University of Melbourne, 35 Poplar Rd (Locked Bag 10), 
      Parkville, Victoria 3052, Australia. Electronic address: 
      barnaby.nelson@orygen.org.au.
FAU - Haug, Elisabeth
AU  - Haug E
AD  - Innlandet Hospital Trust, Department of Acute Psychiatry and Psychosis Treatment, 
      Presteseter 1, 2840 Reinsvoll, Norway. Electronic address: 
      elisabeth.haug@sykehuset-innlandet.no.
FAU - Melle, Ingrid
AU  - Melle I
AD  - NORMENT KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine, 
      University of Oslo, P.O. Box 1039 Blindern, 0315 Oslo, Norway; Division of Mental 
      Health and Addiction, Oslo University Hospital, P.O. Box 1039 Blindern, 0315 
      Oslo, Norway. Electronic address: ingrid.melle@medisin.uio.no.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20190814
PL  - Netherlands
TA  - Schizophr Res
JT  - Schizophrenia research
JID - 8804207
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Affective Disorders, Psychotic/diagnosis/*physiopathology/rehabilitation
MH  - *Ego
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Prognosis
MH  - Psychotic Disorders/diagnosis/*physiopathology/rehabilitation
MH  - Schizophrenia/diagnosis/*physiopathology/rehabilitation
MH  - Young Adult
OTO - NOTNLM
OT  - Bipolar disorder
OT  - Examination of anomalous self-experience
OT  - Longitudinal study
OT  - Outcome
OT  - Schizophrenia
EDAT- 2019/08/20 06:00
MHDA- 2020/10/06 06:00
CRDT- 2019/08/18 06:00
PHST- 2018/11/02 00:00 [received]
PHST- 2019/07/31 00:00 [revised]
PHST- 2019/08/05 00:00 [accepted]
PHST- 2019/08/20 06:00 [pubmed]
PHST- 2020/10/06 06:00 [medline]
PHST- 2019/08/18 06:00 [entrez]
AID - S0920-9964(19)30350-0 [pii]
AID - 10.1016/j.schres.2019.08.009 [doi]
PST - ppublish
SO  - Schizophr Res. 2019 Oct;212:72-78. doi: 10.1016/j.schres.2019.08.009. Epub 2019 
      Aug 14.