PMID- 31422484
OWN - NLM
STAT- MEDLINE
DCOM- 20200601
LR  - 20200601
IS  - 1573-3890 (Electronic)
IS  - 1573-3882 (Linking)
VI  - 15
IP  - 8
DP  - 2019 Aug 17
TI  - Metabolic response of yellow mealworm larvae to two alternative rearing 
      substrates.
PG  - 113
LID - 10.1007/s11306-019-1578-2 [doi]
AB  - INTRODUCTION: Mass insect rearing is becoming increasingly pursued by food and 
      feed industry due to its high sustainability and low environmental impact. Yellow 
      mealworm larvae (Tenebrio molitor) are conventionally reared on wheat bran (WB), 
      but alternative substrates, such as several by-products of the agri-food 
      industry, have shown good prospects for insect rearing. OBJECTIVES: The objective 
      of this study was to investigate on the metabolic and nutritional response of 
      yellow mealworm larvae to dried brewer's spent grains (BSG) and WB used as 
      rearing substrates. METHODS: Proximate, fibre and fatty acid compositions of 
      durum WB and dried BSG were first characterized. Mealworm larvae were fed either 
      WB (WB-L) or BSG (BSG-L) in a trial reproducing a scale rearing condition. Feed 
      efficiency parameters together with proximate and FA composition were determined. 
      Metabolic pathways affected by the dietary treatments were evaluated by means of 
      a targeted metabolomics approach. Proton nuclear magnetic resonance ((1)H NMR) 
      spectra were acquired on lipid and polar extracts of WB-L and BSG-L and then 
      coupled to multivariate data analysis. Absolute quantitative (1)H NMR data were 
      carried out on selected metabolites. RESULTS: BSG-L exhibited better feed 
      conversion ratio and efficiency in conversion of ingested food (P < 0.05) and 
      almost half fat content (P < 0.001) than WB-L. BSG-L also showed higher omega-3 and 
      omega-6 poliunsaturated fatty acids (P < 0.001) and lower content of monounsaturated 
      fatty acids (P < 0.001) than WB-L. BSG-L mobilized body fat towards methylamine 
      accumulation and led to enhanced trehalose catabolism. CONCLUSIONS: Our findings 
      are useful to gain knowledge on the metabolic features that finally affect growth 
      and body composition in reared yellow mealworm larvae.
FAU - Melis, Riccardo
AU  - Melis R
AD  - Porto Conte Ricerche S. r. l, S.P. 55 Porto Conte - Capo Caccia, Km 8.400, Loc. 
      Tramariglio, Alghero, SS, Italy.
FAU - Braca, Angela
AU  - Braca A
AD  - Porto Conte Ricerche S. r. l, S.P. 55 Porto Conte - Capo Caccia, Km 8.400, Loc. 
      Tramariglio, Alghero, SS, Italy.
FAU - Sanna, Roberta
AU  - Sanna R
AD  - Porto Conte Ricerche S. r. l, S.P. 55 Porto Conte - Capo Caccia, Km 8.400, Loc. 
      Tramariglio, Alghero, SS, Italy.
FAU - Spada, Simona
AU  - Spada S
AD  - Porto Conte Ricerche S. r. l, S.P. 55 Porto Conte - Capo Caccia, Km 8.400, Loc. 
      Tramariglio, Alghero, SS, Italy.
FAU - Mulas, Gilberto
AU  - Mulas G
AD  - Porto Conte Ricerche S. r. l, S.P. 55 Porto Conte - Capo Caccia, Km 8.400, Loc. 
      Tramariglio, Alghero, SS, Italy.
FAU - Fadda, Maria Leonarda
AU  - Fadda ML
AD  - CNR - Research Institute on Terrestrial Ecosystems, Traversa la Crucca, 3 Li 
      punti, Sassari, SS, Italy.
FAU - Sassu, Maria Maddalena
AU  - Sassu MM
AD  - CNR - Institute for the Animal Production System in the Mediterranean 
      Environment, Traversa la Crucca, 3 Li punti, Sassari, SS, Italy.
FAU - Serra, Giuseppe
AU  - Serra G
AD  - CNR - Institute of Biometeorology, Traversa la Crucca, 3 Li punti, Sassari, SS, 
      Italy.
FAU - Anedda, Roberto
AU  - Anedda R
AUID- ORCID: 0000-0003-1235-5821
AD  - Porto Conte Ricerche S. r. l, S.P. 55 Porto Conte - Capo Caccia, Km 8.400, Loc. 
      Tramariglio, Alghero, SS, Italy. anedda@portocontericerche.it.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20190817
PL  - United States
TA  - Metabolomics
JT  - Metabolomics : Official journal of the Metabolomic Society
JID - 101274889
RN  - 0 (Dietary Fiber)
RN  - 0 (Fatty Acids)
SB  - IM
MH  - Animal Feed
MH  - Animals
MH  - Dietary Fiber/administration & dosage/analysis/*metabolism
MH  - Fatty Acids/administration & dosage/analysis/*metabolism
MH  - Larva
MH  - *Metabolomics
MH  - Multivariate Analysis
MH  - Proton Magnetic Resonance Spectroscopy
MH  - Tenebrio
OTO - NOTNLM
OT  - Brewer's spent grains
OT  - Insect
OT  - Metabolomics
OT  - Proton NMR
OT  - Tenebrio molitor
OT  - Wheat bran
EDAT- 2019/08/20 06:00
MHDA- 2020/06/02 06:00
CRDT- 2019/08/19 06:00
PHST- 2019/04/12 00:00 [received]
PHST- 2019/08/10 00:00 [accepted]
PHST- 2019/08/19 06:00 [entrez]
PHST- 2019/08/20 06:00 [pubmed]
PHST- 2020/06/02 06:00 [medline]
AID - 10.1007/s11306-019-1578-2 [pii]
AID - 10.1007/s11306-019-1578-2 [doi]
PST - epublish
SO  - Metabolomics. 2019 Aug 17;15(8):113. doi: 10.1007/s11306-019-1578-2.