PMID- 31426828
OWN - NLM
STAT- MEDLINE
DCOM- 20200211
LR  - 20200225
IS  - 1824-7288 (Electronic)
IS  - 1720-8424 (Linking)
VI  - 45
IP  - 1
DP  - 2019 Aug 19
TI  - Current insights in non-invasive ventilation for the treatment of neonatal 
      respiratory disease.
PG  - 105
LID - 10.1186/s13052-019-0707-x [doi]
LID - 105
AB  - Deleterious consequences of the management of respiratory distress syndrome (RDS) 
      with invasive ventilation have led to more in-depth investigation of non-invasive 
      ventilation (NIV) modalities. NIV has significantly and positively altered the 
      treatment outcomes and improved mortality rates of preterm infants with RDS. 
      Among the different NIV modes, nasal intermittent positive pressure ventilation 
      (NIPPV) has shown considerable benefits compared to nasal continuous positive 
      airway pressure (NCPAP). Despite reports of heated humidified high-flow nasal 
      cannula's (HHHFNC) non-inferiority compared to NCPAP, some trials have been 
      terminated due to high treatment failure rates with HHHFNC use. Moreover, RDS 
      management with the combination of INSURE (INtubation SURfactant Extubation) 
      technique and NIV ensures higher success rates. This review elaborates on the 
      currently used various modes of NIV and novel techniques are also briefly 
      discussed.
FAU - Permall, Dhivya Lakshmi
AU  - Permall DL
AD  - Department of Pediatrics, The First Affiliated Hospital of Nanjing Medical 
      University, No 300, Guangzhou Road, Nanjing, Jiangsu, China.
FAU - Pasha, Asfia Banu
AU  - Pasha AB
AD  - Department of Pediatrics, The First Affiliated Hospital of Nanjing Medical 
      University, No 300, Guangzhou Road, Nanjing, Jiangsu, China.
FAU - Chen, Xiao-Qing
AU  - Chen XQ
AD  - Department of Pediatrics, The First Affiliated Hospital of Nanjing Medical 
      University, No 300, Guangzhou Road, Nanjing, Jiangsu, China. zysktz@163.com.
LA  - eng
GR  - BL2014084/Construction Program of Jiangsu Provincial Clinical Research Center 
      Support System/
GR  - 2017CX015/Clinical Research Cultivation Program/
PT  - Journal Article
PT  - Review
DEP - 20190819
PL  - England
TA  - Ital J Pediatr
JT  - Italian journal of pediatrics
JID - 101510759
SB  - IM
MH  - Humans
MH  - Infant, Newborn
MH  - Infant, Premature
MH  - *Noninvasive Ventilation
MH  - Respiratory Distress Syndrome, Newborn/*therapy
PMC - PMC6700989
OTO - NOTNLM
OT  - Continuous positive airway pressure
OT  - Nasal intermittent positive pressure ventilation
OT  - Newborn
OT  - Non-invasive ventilation
OT  - Respiratory distress syndrome
COIS- The authors declare that they have no competing interests.
EDAT- 2019/08/21 06:00
MHDA- 2020/02/12 06:00
PMCR- 2019/08/19
CRDT- 2019/08/21 06:00
PHST- 2018/12/02 00:00 [received]
PHST- 2019/08/13 00:00 [accepted]
PHST- 2019/08/21 06:00 [entrez]
PHST- 2019/08/21 06:00 [pubmed]
PHST- 2020/02/12 06:00 [medline]
PHST- 2019/08/19 00:00 [pmc-release]
AID - 10.1186/s13052-019-0707-x [pii]
AID - 707 [pii]
AID - 10.1186/s13052-019-0707-x [doi]
PST - epublish
SO  - Ital J Pediatr. 2019 Aug 19;45(1):105. doi: 10.1186/s13052-019-0707-x.