PMID- 31429207 OWN - NLM STAT- MEDLINE DCOM- 20200828 LR - 20200828 IS - 1742-7924 (Electronic) IS - 1742-7924 (Linking) VI - 17 IP - 2 DP - 2020 Apr TI - The effect of inspiratory muscle training on fatigue and dyspnea in patients with heart failure: A randomized, controlled trial. PG - e12290 LID - 10.1111/jjns.12290 [doi] AB - AIM: Fatigue and dyspnea are debilitating symptoms in patients with heart failure (HF). The purpose of this study was to evaluate the effects of inspiratory muscle training (IMT) on dyspnea, fatigue and the New York Heart Association (NYHA) functional classification in patients with HF. METHODS: In this prospective, randomized, controlled trial, 84 patients with HF (NYHA classes II-III/IV) with a mean age of 56.62 +/- 9.56 years were randomly assigned to a 6-week IMT (n = 42) or a sham IMT (n = 42) program. The IMT was performed at 40% of the maximal inspiratory pressure (MIP) in the IMT group and at 10% in the sham group. The main outcomes were assessed at baseline and after the intervention and included dyspnea severity scale (Modified Medical Research Council [MMRC], Fatigue Severity Scale [FSS] and the NYHA functional classification (based on the presenting symptoms). RESULTS: The between-group analysis showed significant improvements in dyspnea, fatigue and the NYHA functional classification in the IMT group compared to the sham group (P < .05). The within-group analysis showed significant improvements in dyspnea (from 2.63 +/- 0.79 to 1.38 +/- 0.66, P < .001), fatigue (from 43.36 +/- 8.5 to 28.95 +/- 9.11, P < .001) and the NYHA functional classification (from 2.73 +/- 0.5 to 2.1 +/- 0.6, P = .001) in the IMT group, while fatigue and dyspnea increased significantly in the sham group. CONCLUSIONS: The 6-week home-based IMT was found to be an effective and safe tool for reducing dyspnea and fatigue and improving the NYHA functional classification. CI - (c) 2019 Japan Academy of Nursing Science. FAU - Hossein Pour, Amir Hossein AU - Hossein Pour AH AD - Student Research Committee, Lorestan University of Medical Sciences, Khorramabad, Iran. FAU - Gholami, Mohammad AU - Gholami M AUID- ORCID: 0000-0001-5553-2651 AD - School of Nursing and Midwifery, Lorestan University of Medical Sciences, Khorramabad, Iran. FAU - Saki, Mandana AU - Saki M AD - Social Determinants of Health Research Center, Lorestan University of Medical Sciences, Khorramabad, Iran. FAU - Birjandi, Mehdi AU - Birjandi M AD - Department of Biostatistics and Epidemiology, School of Health and Nutrition, Lorestan University of Medical Sciences, Khorramabad, Iran. LA - eng GR - project code: A-10-1,661-1/Research and Technology Deputy of Lorestan University of Medical Sciences/ PT - Journal Article PT - Randomized Controlled Trial DEP - 20190819 PL - Japan TA - Jpn J Nurs Sci JT - Japan journal of nursing science : JJNS JID - 101227890 SB - IM MH - Aged MH - *Breathing Exercises MH - Dyspnea/complications/*physiopathology MH - Exercise Tolerance MH - Fatigue/complications/*physiopathology MH - Female MH - Heart Failure/complications/*physiopathology MH - Humans MH - Male MH - Middle Aged MH - Prospective Studies MH - Quality of Life MH - Respiratory Muscles/*physiology OTO - NOTNLM OT - dyspnea OT - fatigue OT - heart failure OT - inspiratory muscle training EDAT- 2019/08/21 06:00 MHDA- 2020/08/29 06:00 CRDT- 2019/08/21 06:00 PHST- 2018/08/24 00:00 [received] PHST- 2019/04/18 00:00 [revised] PHST- 2019/06/27 00:00 [accepted] PHST- 2019/08/21 06:00 [pubmed] PHST- 2020/08/29 06:00 [medline] PHST- 2019/08/21 06:00 [entrez] AID - 10.1111/jjns.12290 [doi] PST - ppublish SO - Jpn J Nurs Sci. 2020 Apr;17(2):e12290. doi: 10.1111/jjns.12290. Epub 2019 Aug 19.