PMID- 31440145
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20200929
IS  - 1662-5145 (Print)
IS  - 1662-5145 (Electronic)
IS  - 1662-5145 (Linking)
VI  - 13
DP  - 2019
TI  - Brain Derived Neurotropic Factors in Speed vs. Inclined Treadmill in Young Adult 
      Healthy Male With Occult Balance Disorder.
PG  - 33
LID - 10.3389/fnint.2019.00033 [doi]
LID - 33
AB  - Background: There is an increase in fall risk among elders and young adults 
      consecutively due to various causes. Occult balance disorder may be among the 
      abnormal causes of falling in young adults as well as elders. The One Leg Stance 
      (OLS) test is used to diagnose this balance performance; it's a proven test to 
      measure static balance function which would lead to dynamic balance function. It 
      has been proven that aside from cardiopulmonary exercises, treadmill workout can 
      be used as a dynamic balance exercise. The Brain Derived Neurotropic Factor 
      (BDNF) increases balance function through the treadmill exercise (the inclination 
      and speed). This hormone is one of the tropical hormones generated in neurons, 
      muscles, hematopoietic tissue and it is characterized by neurons morphology 
      regulation and neuroplasticity. Materials and Methods: We divided 20 healthy 
      young adult men to work out on inclination and speed groups treadmill exercise. 
      The workout lasted for 2 weeks. We immediately observed the effect of exercise on 
      serum BDNF as two tests were taken on before and 30 min after the workout. 
      Result: There were significant increases of pre-exercise serum BDNF level in 
      speed group between the first and the last exercise (p = 0.001), post-exercise 
      between the first day and the last exercise (p = 0.001). No significant increase 
      of serum BDNF in speed group pre- and post-exercise on the first exercise (p = 
      0.159), pre- and post-exercise on the last exercise (p = 0.892). There was no 
      significant increase in serum BDNF in inclination group on all parameters (p > 
      0.05). The serum BDNF is actually a neurotropic factor that affects not just the 
      neuronal system, but also molecular energy and metabolism regulation. This serum 
      is dependent on the aerobic capacity, lactate production, muscle calcium uptake, 
      and muscle fiber type used in exercises. Furthermore, the serum BDNF is increased 
      by treadmill exercises in escalated speed. Conclusion: Treadmill exercises with 
      average speed escalation increase the serum BDNF.
FAU - Yulinda, Stephanie T
AU  - Yulinda ST
AD  - Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Dr. 
      Soetomo General Academic Hospital, Universitas Airlangga, Surabaya, Indonesia.
FAU - Tinduh, Damayanti
AU  - Tinduh D
AD  - Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Dr. 
      Soetomo General Academic Hospital, Universitas Airlangga, Surabaya, Indonesia.
FAU - Wardhani, Lukitra
AU  - Wardhani L
AD  - Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Dr. 
      Soetomo General Academic Hospital, Universitas Airlangga, Surabaya, Indonesia.
FAU - Laswati, Hening
AU  - Laswati H
AD  - Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Dr. 
      Soetomo General Academic Hospital, Universitas Airlangga, Surabaya, Indonesia.
FAU - Wibisono, Sony
AU  - Wibisono S
AD  - Department of Internal Medicine, Faculty of Medicine, Dr. Soetomo General 
      Academic Hospital, Universitas Airlangga, Surabaya, Indonesia.
FAU - Soenarnatalina, Melaniani
AU  - Soenarnatalina M
AD  - Department of Biostatistics and Population Studies, Faculty of Public Health, 
      Universitas Airlangga, Surabaya, Indonesia.
LA  - eng
PT  - Journal Article
DEP - 20190806
PL  - Switzerland
TA  - Front Integr Neurosci
JT  - Frontiers in integrative neuroscience
JID - 101477950
PMC - PMC6691687
OTO - NOTNLM
OT  - brain derived neurotropic factor
OT  - inclined treadmill
OT  - occult balance disorder
OT  - speed treadmill
OT  - young adult healthy male
EDAT- 2019/08/24 06:00
MHDA- 2019/08/24 06:01
PMCR- 2019/01/01
CRDT- 2019/08/24 06:00
PHST- 2018/10/11 00:00 [received]
PHST- 2019/07/11 00:00 [accepted]
PHST- 2019/08/24 06:00 [entrez]
PHST- 2019/08/24 06:00 [pubmed]
PHST- 2019/08/24 06:01 [medline]
PHST- 2019/01/01 00:00 [pmc-release]
AID - 10.3389/fnint.2019.00033 [doi]
PST - epublish
SO  - Front Integr Neurosci. 2019 Aug 6;13:33. doi: 10.3389/fnint.2019.00033. 
      eCollection 2019.