PMID- 31440744
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20200928
IS  - 2573-9530 (Electronic)
IS  - 2573-9530 (Linking)
VI  - 3
DP  - 2019
TI  - Breast Cancer Incidence and Mortality by Molecular Subtype: Statewide Age and 
      Racial/Ethnic Disparities in New Jersey.
PG  - e1-e17
LID - 10.9777/chd.2019.1012 [doi]
AB  - The objective of this study was to assess breast cancer incidence and mortality 
      rates by molecular subtype for cases diagnosed in New Jersey. Data on all 
      primary, histologically confirmed, invasive breast cancers diagnosed among women 
      between January 1, 2008 and December 31, 2013 were retrieved from the New Jersey 
      State Cancer Registry. Age-adjusted incidence rates were calculated for each 
      subtype, by ageandrace/ethnicity. Logistic regression models, Cox proportional 
      hazards models, and Kaplan Meier curves were used to describe the relative risks 
      for breast cancer incidence, mortality, and survival, respectively. In this 
      population-based sample of 32,770 breast cancer cases, non-Hispanic Blacks (NHBs) 
      had the highest triple-negative breast cancer (TNBC) incidence rate (17.8 per 
      100,000, 95% CI 16.5-19.2) compared to other races/ethnicities. NHBs had also 
      higher odds of TNBC (OR 2.1, 95% CI 1.95-2.36) and higher hazards of death when 
      diagnosed with TNBC (HR 1.28, 95% CI 1.05-1.56), luminal A (HR 1.64, 95% CI 
      1.41-1.91), or luminal B (HR 1.54, 95% CI 1.10-2.15) than non-Hispanic Whites 
      (NHWs). Younger women (20-39 years) had higher odds of TNBC (OR 1.77, 95% CI 
      1.54-2.02) and luminal B (OR 1.56, 95% CI 1.35-1.80) compared to women 50-64 
      years; minority women had higher odds of non-luminal HER2-expressing and lower 
      odds of luminal A than NHWs. TNBC was associated with the poorest survival rates. 
      These findings highlight a need for enhanced screening to promote earlier 
      diagnosis and improve breast cancer outcomes, particularly in minorities and 
      younger women, which will be essential for achieving health equity.
FAU - Kulkarni, Aishwarya
AU  - Kulkarni A
AD  - Department of Epidemiology, Rutgers School of Public Health, Piscataway, NJ, USA.
AD  - Rutgers Cancer Institute of New Jersey, New Brunswick, NJ, USA.
AD  - New Jersey State Cancer Registry, State of New Jersey, Department of Health, 
      Trenton, NJ, USA.
FAU - Stroup, Antoinette M
AU  - Stroup AM
AD  - Department of Epidemiology, Rutgers School of Public Health, Piscataway, NJ, USA.
AD  - Rutgers Cancer Institute of New Jersey, New Brunswick, NJ, USA.
AD  - New Jersey State Cancer Registry, State of New Jersey, Department of Health, 
      Trenton, NJ, USA.
FAU - Paddock, Lisa E
AU  - Paddock LE
AD  - Department of Epidemiology, Rutgers School of Public Health, Piscataway, NJ, USA.
AD  - Rutgers Cancer Institute of New Jersey, New Brunswick, NJ, USA.
AD  - New Jersey State Cancer Registry, State of New Jersey, Department of Health, 
      Trenton, NJ, USA.
FAU - Hill, Stephanie M
AU  - Hill SM
AD  - Rutgers Cancer Institute of New Jersey, New Brunswick, NJ, USA.
AD  - New Jersey State Cancer Registry, State of New Jersey, Department of Health, 
      Trenton, NJ, USA.
FAU - Plascak, Jesse J
AU  - Plascak JJ
AD  - Department of Epidemiology, Rutgers School of Public Health, Piscataway, NJ, USA.
AD  - Rutgers Cancer Institute of New Jersey, New Brunswick, NJ, USA.
FAU - Llanos, Adana A M
AU  - Llanos AAM
AD  - Department of Epidemiology, Rutgers School of Public Health, Piscataway, NJ, USA.
AD  - Rutgers Cancer Institute of New Jersey, New Brunswick, NJ, USA.
LA  - eng
GR  - K01 CA193527/CA/NCI NIH HHS/United States
GR  - P30 CA072720/CA/NCI NIH HHS/United States
PT  - Journal Article
DEP - 20190819
PL  - United States
TA  - Cancer Health Disparities
JT  - Cancer health disparities
JID - 101728460
PMC - PMC6706320
MID - NIHMS999914
OTO - NOTNLM
OT  - breast cancer
OT  - disparities
OT  - diverse population
OT  - incidence
OT  - molecular subtype
OT  - mortality
OT  - surveillance
COIS- Conflict of interest The authors have no conflicts of interest to declare.
EDAT- 2019/08/24 06:00
MHDA- 2019/08/24 06:01
PMCR- 2019/08/22
CRDT- 2019/08/24 06:00
PHST- 2019/08/24 06:00 [entrez]
PHST- 2019/08/24 06:00 [pubmed]
PHST- 2019/08/24 06:01 [medline]
PHST- 2019/08/22 00:00 [pmc-release]
AID - 10.9777/chd.2019.1012 [doi]
PST - ppublish
SO  - Cancer Health Disparities. 2019;3:e1-e17. doi: 10.9777/chd.2019.1012. Epub 2019 
      Aug 19.