PMID- 31440848
OWN - NLM
STAT- MEDLINE
DCOM- 20191113
LR  - 20200502
IS  - 1573-2959 (Electronic)
IS  - 0167-6369 (Linking)
VI  - 191
IP  - 9
DP  - 2019 Aug 22
TI  - Residue distribution and risk assessment of two macrocyclic lactone insecticides 
      in green onion using micro-liquid-liquid extraction (MLLE) technique coupled with 
      liquid chromatography tandem mass spectrometry.
PG  - 584
LID - 10.1007/s10661-019-7752-1 [doi]
AB  - A micro-liquid-liquid extraction (MLLE) technique coupled with liquid 
      chromatography tandem mass spectrometry (LC-MS/MS) analysis was established and 
      validated to determine the residues of two macrocyclic lactone insecticides 
      (spinetoram and spinosad) in green onion. The limit of quantification (LOQ) of 
      the method, as demonstrated by the lowest acceptable recovery level, was 0.01 mg 
      kg(-1), and the obtained recoveries were 78.3-93.4% with relative standard 
      deviations (RSDs) < 12.5%. The method was then applied for analyzing field 
      samples collected after treatment with the tested insecticides under Egyptian 
      open-field condition. The decline pattern, terminal residues, and dietary risk 
      assessment of spinetoram and spinosad residues in green onion were evaluated for 
      food safety. Spinetoram and spinosad residues' decline in green onion followed 
      first-order kinetics with the half-lives of 1.2 and 1.42 days, respectively. 
      Based on the results, the required period to reach their respective maximum 
      residue limits (MRLs) was 1 and 0 days for spinetoram and spinosad residues in 
      green onion, respectively, which indicates a short persistence level and high 
      degradation rate. The results suggest that there is no unacceptable chronic or 
      acute risk to human health from the consumption of green onion treated with 
      spinetoram and spinosad according to the uses considered.
FAU - Malhat, Farag
AU  - Malhat F
AUID- ORCID: 0000-0002-5115-876X
AD  - Pesticide Residues and Environmental Pollution Department, Central Agricultural 
      Pesticide Laboratory, Agricultural Research Center, Dokki, Giza, 12618, Egypt. 
      farag_malhat@yahoo.com.
FAU - Abdallah, Osama
AU  - Abdallah O
AD  - Pesticide Residues and Environmental Pollution Department, Central Agricultural 
      Pesticide Laboratory, Agricultural Research Center, Dokki, Giza, 12618, Egypt.
AD  - Food Safety Laboratory, Al-Qassim Municipality, Buraydah, Al-Qassim, Saudi 
      Arabia.
LA  - eng
PT  - Journal Article
DEP - 20190822
PL  - Netherlands
TA  - Environ Monit Assess
JT  - Environmental monitoring and assessment
JID - 8508350
RN  - 0 (Drug Combinations)
RN  - 0 (Insecticides)
RN  - 0 (Lactones)
RN  - 0 (Macrolides)
RN  - 0 (Pesticide Residues)
RN  - XPA88EAP6V (spinosad)
RN  - YGZ1037ELN (spinetoram)
SB  - IM
MH  - Chromatography, Liquid/methods
MH  - Drug Combinations
MH  - Egypt
MH  - Environmental Monitoring
MH  - Half-Life
MH  - Insecticides/*analysis
MH  - Lactones
MH  - Liquid Phase Microextraction
MH  - Macrolides/*analysis
MH  - Onions/*chemistry
MH  - Pesticide Residues/*analysis
MH  - Risk Assessment
MH  - Tandem Mass Spectrometry/methods
OTO - NOTNLM
OT  - Dietary risk assessment
OT  - Dissipation behavior
OT  - MLLE method
OT  - Macrocyclic lactones
OT  - Residue distribution
EDAT- 2019/08/24 06:00
MHDA- 2019/11/14 06:00
CRDT- 2019/08/24 06:00
PHST- 2019/01/21 00:00 [received]
PHST- 2019/08/09 00:00 [accepted]
PHST- 2019/08/24 06:00 [entrez]
PHST- 2019/08/24 06:00 [pubmed]
PHST- 2019/11/14 06:00 [medline]
AID - 10.1007/s10661-019-7752-1 [pii]
AID - 10.1007/s10661-019-7752-1 [doi]
PST - epublish
SO  - Environ Monit Assess. 2019 Aug 22;191(9):584. doi: 10.1007/s10661-019-7752-1.