PMID- 31441437
OWN - NLM
STAT- MEDLINE
DCOM- 20200423
LR  - 20200423
IS  - 0974-7559 (Electronic)
IS  - 0019-6061 (Linking)
VI  - 56
IP  - 10
DP  - 2019 Oct 15
TI  - Comparison of Soybean-based Oil and MCT-olive-fish-soy Oil Intravenous Lipid 
      Emulsions on Soluble Adhesion Markers in Preterm Neonates with Sepsis: A 
      Randomized Controlled Trial.
PG  - 841-844
LID - S097475591600134 [pii]
AB  - OBJECTIVE: To compare the effects of two different intravenous lipid emulsions on 
      soluble adhesion markers in preterm infants with sepsis. METHODS: This randomized 
      controlled pilot trial was conducted from February 2016 to February 2017. 40 
      preterm infants with sepsis were enrolled and assigned to receive either Medium 
      chain triglyceride-Olive-Fish-Soy lipid emulsion (MOFS-LE) or soybean oil-based 
      lipid emulsion (S-LE). Outcomes of the study were changes in sICAM-1 and 
      leukocyte integrin b2 levels, and growth after 7 days of intervention. RESULTS: 
      Leukocyte integrin b2 was significantly higher in MOFS-LE group. No statistically 
      significant differences were observed for sICAM-1, duration of mechanical 
      ventilation and antibiotics treatment, and mortality rate. CONCLUSIONS: Leukocyte 
      integrin b2 was significantly higher in preterm septic neonates who received 
      MOFS-LE.
FAU - Abdelkareem, Mohammed
AU  - Abdelkareem M
AD  - Department of Pediatrics, Faculty of Medicine, Mansoura University, Mansoura, 
      Egypt.
FAU - Wahba, Yahya
AU  - Wahba Y
AD  - Department of Pediatrics, Faculty of Medicine, Mansoura University, Mansoura, 
      Egypt. Correspondence to: Dr Yahya Wahba, Assistant Professor, Department of 
      Pediatrics, Faculty of Medicine, Mansoura University, 35516, Mansoura, Egypt. 
      wahbayahya2007@mans.edu.eg.
FAU - Shouman, Basma
AU  - Shouman B
AD  - Department of Pediatrics, Faculty of Medicine, Mansoura University, Mansoura, 
      Egypt.
FAU - Mesbah, Abeer
AU  - Mesbah A
AD  - Departments of Clinical Pathology, Faculty of Medicine, Mansoura University, 
      Mansoura, Egypt.
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Randomized Controlled Trial
DEP - 20190810
PL  - India
TA  - Indian Pediatr
JT  - Indian pediatrics
JID - 2985062R
RN  - 0 (Biomarkers)
RN  - 0 (Fat Emulsions, Intravenous)
RN  - 0 (Fish Oils)
RN  - 0 (ICAM1 protein, human)
RN  - 0 (Interferon-alpha)
RN  - 126547-89-5 (Intercellular Adhesion Molecule-1)
RN  - 8001-22-7 (Soybean Oil)
SB  - IM
MH  - Biomarkers/blood
MH  - Child Development/*physiology
MH  - Double-Blind Method
MH  - Egypt
MH  - Fat Emulsions, Intravenous/*administration & dosage
MH  - Female
MH  - Fish Oils/*administration & dosage
MH  - Humans
MH  - Infant
MH  - Infant, Newborn
MH  - Infant, Premature
MH  - Intensive Care Units, Neonatal
MH  - Intercellular Adhesion Molecule-1/blood
MH  - Interferon-alpha/blood
MH  - Male
MH  - Pilot Projects
MH  - Sepsis/diagnosis/*therapy
MH  - Soybean Oil/*administration & dosage
MH  - Statistics, Nonparametric
MH  - Treatment Outcome
EDAT- 2019/08/24 06:00
MHDA- 2020/04/24 06:00
CRDT- 2019/08/24 06:00
PHST- 2019/08/24 06:00 [pubmed]
PHST- 2020/04/24 06:00 [medline]
PHST- 2019/08/24 06:00 [entrez]
AID - S097475591600134 [pii]
PST - ppublish
SO  - Indian Pediatr. 2019 Oct 15;56(10):841-844. Epub 2019 Aug 10.