PMID- 3144172
OWN - NLM
STAT- MEDLINE
DCOM- 19890117
LR  - 20180330
IS  - 0002-9165 (Print)
IS  - 0002-9165 (Linking)
VI  - 48
IP  - 6
DP  - 1988 Dec
TI  - Increased plasma carnitine in trauma patients given lipid-supplemented total 
      parenteral nutrition.
PG  - 1400-2
AB  - The purpose of this study was to determine the effects of altering the fuel 
      substrate mix of total parenteral nutrition (TPN) on plasma and urinary carnitine 
      in trauma patients. TPN solutions were either 100% carbohydrate (CHO) based or 
      lipid based (70% CHO, 30% lipid). There were statistically significant (p less 
      than 0.05) increases in plasma levels of free carnitine, short-chain acyl 
      carnitine, and total carnitine in trauma patients receiving lipid-based TPN. No 
      significant differences in urinary carnitine excretion were noted between groups. 
      We conclude that the use of lipids in the TPN of trauma patients leads to an 
      alteration in plasma carnitine metabolism.
FAU - Davis, A T
AU  - Davis AT
AD  - Department of Surgery, Michigan State University, Grand Rapids.
FAU - Albrecht, R M
AU  - Albrecht RM
FAU - Scholten, D J
AU  - Scholten DJ
FAU - Morgan, R E
AU  - Morgan RE
LA  - eng
PT  - Clinical Trial
PT  - Controlled Clinical Trial
PT  - Journal Article
PL  - United States
TA  - Am J Clin Nutr
JT  - The American journal of clinical nutrition
JID - 0376027
RN  - 0 (Dietary Fats)
RN  - S7UI8SM58A (Carnitine)
SB  - IM
MH  - Adult
MH  - Carnitine/*blood/urine
MH  - Dietary Fats/*administration & dosage
MH  - Female
MH  - Humans
MH  - Male
MH  - *Parenteral Nutrition, Total
MH  - Wounds and Injuries/blood/*therapy
EDAT- 1988/12/01 00:00
MHDA- 1988/12/01 00:01
CRDT- 1988/12/01 00:00
PHST- 1988/12/01 00:00 [pubmed]
PHST- 1988/12/01 00:01 [medline]
PHST- 1988/12/01 00:00 [entrez]
AID - 10.1093/ajcn/48.6.1400 [doi]
PST - ppublish
SO  - Am J Clin Nutr. 1988 Dec;48(6):1400-2. doi: 10.1093/ajcn/48.6.1400.