PMID- 31443168 OWN - NLM STAT- MEDLINE DCOM- 20200625 LR - 20200625 IS - 1648-9144 (Electronic) IS - 1010-660X (Print) IS - 1010-660X (Linking) VI - 55 IP - 8 DP - 2019 Aug 15 TI - Electrical Changes in Polish Patients with Chronic Heart Failure: Preliminary Observations. LID - 10.3390/medicina55080484 [doi] LID - 484 AB - Introduction: Direct parameters resistance (R), reactance (Xc), phase angle (PA), capacitance of membrane (Cm), and impedance ratio (Z200/Z5)) determined by bioelectrical impedance analysis (BIA) detect changes in tissue electrical properties and have been found to be a marker of cell membrane function in various diseases. Materials and Method: The cross-sectional study was conducted to investigate whether direct bioimpedance parameters differ in a group of heart failure (HF) patients divided on the basis of the New York Heart Association (NYHA) functional classes I-II and III-IV. BIA was evaluated in 100 patients with HF treated in Clinic of Cardiology and Internal Medicine, Department of Cardiology, Military Hospital, Lublin. Results: In men, lower PA values (p = 0.01), Xc (p < 0.01), Cm (p = 0.02), and higher values of the Z200/Z5 ratio (p < 0.01) were observed in patients classified into NYHA groups III and IV in comparison to those with lower stages of disease. Similar correlations were noted in women (only Cm differences were insignificant). In addition, in men, C-Reactive Protein (CRP) correlated negatively with PA (p < 0.01), Xc (p < 0.01), and Cm (p < 0.01) and positively with the Z200/Z5 index (p < 0.01). There were no similar correlations observed in women. Conclusion: Patients with advanced CHF have altered electrical values. Changes in electrical values may directly reflect tissues as well as the whole-body condition. FAU - Sobieszek, Grzegorz AU - Sobieszek G AD - Clinic of Cardiology and Internal Medicine, Department of Cardiology, Military Hospital, 20-093 Lublin, Poland. FAU - Mlak, Radoslaw AU - Mlak R AUID- ORCID: 0000-0001-7399-8340 AD - Human Physiology Department, Medical University of Lublin, 20-080 Lublin, Poland. FAU - Skwarek-Dziekanowska, Aneta AU - Skwarek-Dziekanowska A AD - Clinic of Cardiology and Internal Medicine, Department of Cardiology, Military Hospital, 20-093 Lublin, Poland. FAU - Jurzak-Mysliwy, Aneta AU - Jurzak-Mysliwy A AD - Clinic of Cardiology and Internal Medicine, Department of Cardiology, Military Hospital, 20-093 Lublin, Poland. FAU - Homa-Mlak, Iwona AU - Homa-Mlak I AD - Human Physiology Department, Medical University of Lublin, 20-080 Lublin, Poland. iwona.homa.mlak@gmail.com. FAU - Malecka-Massalska, Teresa AU - Malecka-Massalska T AD - Human Physiology Department, Medical University of Lublin, 20-080 Lublin, Poland. LA - eng PT - Journal Article DEP - 20190815 PL - Switzerland TA - Medicina (Kaunas) JT - Medicina (Kaunas, Lithuania) JID - 9425208 RN - 0 (Biomarkers) SB - IM MH - Adult MH - Aged MH - Aged, 80 and over MH - Biomarkers/analysis MH - Chronic Disease MH - Cross-Sectional Studies MH - *Electric Impedance MH - Female MH - Heart/physiopathology MH - Heart Conduction System/*physiopathology MH - Heart Failure/*physiopathology MH - Humans MH - Male MH - Middle Aged MH - Poland PMC - PMC6724034 OTO - NOTNLM OT - bioelectrical impedance analysis (BIA) OT - chronic heart failure (CHF) OT - electrical changes OT - phase angle (PA) COIS- The authors declare no conflict of interest. EDAT- 2019/08/25 06:00 MHDA- 2020/06/26 06:00 PMCR- 2019/08/15 CRDT- 2019/08/25 06:00 PHST- 2019/06/20 00:00 [received] PHST- 2019/08/07 00:00 [revised] PHST- 2019/08/13 00:00 [accepted] PHST- 2019/08/25 06:00 [entrez] PHST- 2019/08/25 06:00 [pubmed] PHST- 2020/06/26 06:00 [medline] PHST- 2019/08/15 00:00 [pmc-release] AID - medicina55080484 [pii] AID - medicina-55-00484 [pii] AID - 10.3390/medicina55080484 [doi] PST - epublish SO - Medicina (Kaunas). 2019 Aug 15;55(8):484. doi: 10.3390/medicina55080484.