PMID- 31451379
OWN - NLM
STAT- MEDLINE
DCOM- 20200113
LR  - 20211204
IS  - 1532-2653 (Electronic)
IS  - 0967-5868 (Linking)
VI  - 69
DP  - 2019 Nov
TI  - Solitary intraventricular Hodgkin lymphoma post-transplant lymphoproliferative 
      disease (HL-PTLD): Case report.
PG  - 269-272
LID - S0967-5868(19)31141-5 [pii]
LID - 10.1016/j.jocn.2019.08.053 [doi]
AB  - Lymphomas affecting the central nervous system (CNS), both primarily and 
      secondarily, are uncommon malignancies. Immunosuppressed states, including 
      iatrogenic immunosuppression following organ transplantation, are the most 
      significant risk factors for developing primary CNS lymphoma (PCNSL). 
      Post-transplant lymphoproliferative disease (PTLD) is a well described 
      complication following bone marrow or solid organ transplantation. PTLD is 
      usually a systemic disease with occasional CNS involvement. The incidence of CNS 
      involvement in PTLD is low, and the majority of these cases tend to be PCNSL. 
      Hodgkin lymphoma PTLD (HL-PTLD) constitutes only a very small percentage of PTLD. 
      We report a rare case of a primary intraventricular CNS classical HL-PTLD in a 
      male patient, 18 years following renal transplantation. The location allowed for 
      safe neurosurgical intervention which resolved the symptom of elevated 
      intracranial pressure and allowed for induction of a Rituximab-based chemotherapy 
      regimen. Both the ventricular location of the PTLD and Hodgkin Lymphoma PTLD are 
      themselves individually quite rare and have not previously been reported 
      together. The unique location allowed safe neurosurgical intervention which 
      quickly resolved the symptom of elevated intracranial pressure and allowed for 
      induction of a Rituximab-based chemotherapy regimen.
CI  - Copyright (c) 2019 Elsevier Ltd. All rights reserved.
FAU - Azriel, Amit
AU  - Azriel A
AD  - Department of Neurosurgery, The Royal Melbourne Hospital, Victoria, Australia; 
      Department of Surgery, The University of Melbourne, Victoria, Australia. 
      Electronic address: azriela@post.bgu.ac.il.
FAU - Towner, James E
AU  - Towner JE
AD  - Department of Neurosurgery, The Royal Melbourne Hospital, Victoria, Australia; 
      Department of Neurosurgery, University of Rochester Medical Center, Rochester, 
      NY, USA.
FAU - Gaillard, Frank
AU  - Gaillard F
AD  - Department of Radiology, The Royal Melbourne Hospital, Parkville, Victoria, 
      Australia; Faculty of Medicine, Dentistry, and Health Sciences, The University of 
      Melbourne, Australia.
FAU - Box, Georgia
AU  - Box G
AD  - Department of Radiology, The Royal Melbourne Hospital, Parkville, Victoria, 
      Australia.
FAU - Rogers, TeWhiti
AU  - Rogers T
AD  - Department of Pathology, The Royal Melbourne Hospital, Victoria, Australia.
FAU - Morokoff, Andrew
AU  - Morokoff A
AD  - Department of Neurosurgery, The Royal Melbourne Hospital, Victoria, Australia; 
      Department of Surgery, The University of Melbourne, Victoria, Australia.
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20190823
PL  - Scotland
TA  - J Clin Neurosci
JT  - Journal of clinical neuroscience : official journal of the Neurosurgical Society 
      of Australasia
JID - 9433352
SB  - IM
MH  - Cerebral Ventricle Neoplasms/*immunology
MH  - Epstein-Barr Virus Infections/complications/immunology
MH  - Hodgkin Disease/*immunology
MH  - Humans
MH  - *Immunocompromised Host
MH  - Immunosuppression Therapy/adverse effects
MH  - *Kidney Transplantation
MH  - Male
MH  - Middle Aged
MH  - Risk Factors
OTO - NOTNLM
OT  - CNS
OT  - Hodgkin lymphoma
OT  - Intraventricular tumors
OT  - PTLD
EDAT- 2019/08/28 06:00
MHDA- 2020/01/14 06:00
CRDT- 2019/08/28 06:00
PHST- 2019/06/10 00:00 [received]
PHST- 2019/08/06 00:00 [accepted]
PHST- 2019/08/28 06:00 [pubmed]
PHST- 2020/01/14 06:00 [medline]
PHST- 2019/08/28 06:00 [entrez]
AID - S0967-5868(19)31141-5 [pii]
AID - 10.1016/j.jocn.2019.08.053 [doi]
PST - ppublish
SO  - J Clin Neurosci. 2019 Nov;69:269-272. doi: 10.1016/j.jocn.2019.08.053. Epub 2019 
      Aug 23.