PMID- 31469447
OWN - NLM
STAT- MEDLINE
DCOM- 20201208
LR  - 20201214
IS  - 1468-3083 (Electronic)
IS  - 0926-9959 (Linking)
VI  - 34
IP  - 1
DP  - 2020 Jan
TI  - A systematic review of outcome reporting in laser treatments for dermatological 
      diseases.
PG  - 47-53
LID - 10.1111/jdv.15928 [doi]
AB  - The standardization of outcome reporting is crucial for interpretation and 
      comparison of studies related to laser treatment of skin disorders. In 
      collaboration with the Cochrane Skin-Core Outcome Set Initiative (CS-COUSIN), a 
      procedure has been proposed to find consensus on the most important generic 
      outcome domains (what to measure) for implementation in the international Laser 
      TrEAtment in Dermatology (LEAD) registry. As the first step in the development of 
      a generic outcome set for the LEAD registry, we undertook a systematic review to 
      identify outcomes, outcome measurement instruments, methods and definitions 
      reported in recently published literature of laser treatments for skin disorders. 
      A systematic search was conducted and generated a total of 707 papers. We 
      assessed 150 studies including all types of studies involving laser treatments 
      for the skin. Two researchers independently extracted the type, definition and 
      frequency of all outcomes and used outcome measurement instruments. We identified 
      105 verbatim outcomes that were categorized into eight domains recommended by the 
      COMET framework: appearance, long-term effects, physician and patient-reported 
      physical signs, satisfaction, health-related quality of life, psychological 
      functioning and adverse events. Heterogeneity in outcome reporting (e.g. 
      categories and outcome measurement instruments) was high, and definitions were 
      insufficiently reported. There was a clear under representation of life impact 
      domains, including satisfaction (23%) quality of life (3%) and psychological 
      functioning (1%). Outcome reporting concerning laser treatments for the skin is 
      heterogeneous. Standardized outcomes are needed for improving evidence synthesis. 
      Results of this review will be used in the next step to reach consensus between 
      stakeholders on the outcome domains to be implemented in the LEAD registry.
CI  - (c) 2019 European Academy of Dermatology and Venereology.
FAU - Fransen, F
AU  - Fransen F
AUID- ORCID: 0000-0003-0550-7970
AD  - Department of Dermatology, Amsterdam UMC, Amsterdam, The Netherlands.
FAU - Tio, D C K S
AU  - Tio DCKS
AD  - Department of Dermatology, Amsterdam UMC, Amsterdam, The Netherlands.
FAU - Prinsen, C A C
AU  - Prinsen CAC
AD  - Department of Epidemiology and Biostatistics, Amsterdam Public Health Research 
      Institute, Amsterdam UMC, Vrije Universiteit, Amsterdam, The Netherlands.
FAU - Haedersdal, M
AU  - Haedersdal M
AD  - Massachusetts General Hospital, Harvard Medical School Boston, Boston, MA, USA.
AD  - Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark.
FAU - Hedelund, L
AU  - Hedelund L
AD  - Department of Dermatology, Aarhus University Hospital, Aarhus, Denmark.
FAU - Laubach, H J
AU  - Laubach HJ
AD  - Department of Dermatology and Venereology, Geneva University Hospitals (HUG), 
      Geneva, Switzerland.
FAU - Marini, L
AU  - Marini L
AD  - SDC - The Skin Doctors' Center, Trieste, Italy.
FAU - Paasch, U
AU  - Paasch U
AD  - Department of Dermatology, Venereology and Allergy, University of Leipzig, 
      Leipzig, Germany.
FAU - Passeron, T
AU  - Passeron T
AUID- ORCID: 0000-0002-0797-6570
AD  - Department of Dermatology, University of Cote d'Azur, University Hospital Nice, 
      Nice, France.
AD  - Centre Mediteraneen de Medecine Moleculaire (C3M), INSERM U1065, team 12, 
      University of Cote d'Azur, Nice, France.
FAU - Wolkerstorfer, A
AU  - Wolkerstorfer A
AD  - Department of Dermatology, Amsterdam UMC, Amsterdam, The Netherlands.
LA  - eng
GR  - EADV Project proposal reference number 2017-035/European Academy of Dermatology 
      and Venereology (EADV)/
PT  - Journal Article
PT  - Systematic Review
DEP - 20191010
PL  - England
TA  - J Eur Acad Dermatol Venereol
JT  - Journal of the European Academy of Dermatology and Venereology : JEADV
JID - 9216037
SB  - IM
MH  - Humans
MH  - *Laser Therapy
MH  - Outcome Assessment, Health Care
MH  - Skin Diseases/*therapy
EDAT- 2019/08/31 06:00
MHDA- 2020/12/15 06:00
CRDT- 2019/08/31 06:00
PHST- 2019/01/22 00:00 [received]
PHST- 2019/08/14 00:00 [accepted]
PHST- 2019/08/31 06:00 [pubmed]
PHST- 2020/12/15 06:00 [medline]
PHST- 2019/08/31 06:00 [entrez]
AID - 10.1111/jdv.15928 [doi]
PST - ppublish
SO  - J Eur Acad Dermatol Venereol. 2020 Jan;34(1):47-53. doi: 10.1111/jdv.15928. Epub 
      2019 Oct 10.