PMID- 31471881
OWN - NLM
STAT- MEDLINE
DCOM- 20200731
LR  - 20200731
IS  - 1573-7438 (Electronic)
IS  - 0049-4747 (Linking)
VI  - 52
IP  - 2
DP  - 2020 Mar
TI  - Effect of a trace mineral injection at weaning on growth, antioxidant enzymes 
      activity, and immune system in Nellore calves.
PG  - 881-886
LID - 10.1007/s11250-019-02056-0 [doi]
AB  - The objective of this study was to evaluate the effects of injectable trace 
      minerals (ITM) at the time of weaning on growth, antioxidant, and immune response 
      of Nellore (Bos indicus) calves. Weaned calves (n = 159; 213 +/- 32 kg) were 
      stratified by body weight (BW) and randomly assigned to 1 of 2 treatments: 
      injection (1 mL/45 kg of BW) of saline or ITM. Saline solution consisted of 0.9% 
      NaCl, whereas ITM had 60, 10, 5, and 15 mg/mL of Zn, Mn, Se, and Cu, 
      respectively. The application of ITM increased (P </= 0.04) the plasma 
      concentrations of superoxide dismutase on day 7 and plasma glutathione peroxidase 
      on day 7 and day 21. The ITM calves had greater leukocyte concentration on day 64 
      (P = 0.04), whereas neutrophil and mast cell concentrations did not differ 
      (P >/= 0.67) between treatments. The ITM calves tended (P </= 0.08) to have greater 
      concentrations of lymphocytes on day 64 and eosinophils on day 21, but not 
      (P >/= 0.15) monocytes, erythrocytes, hemoglobin, hematocrit, mean corpuscular 
      volume, and mean corpuscular hemoglobin compared to saline calves. The ITM calves 
      had less mean corpuscular hemoglobin concentration (MCHC; P = 0.02) and tended to 
      have increased platelet concentrations on day 21 (P = 0.08). Growth performance 
      did not differ between treatments (P >/= 0.78). Thus, ITM at weaning did not impact 
      growth performance, but increased plasma concentrations of antioxidant enzymes 
      and blood platelets, improved components of the immune system, and reduced MCHC 
      of Nellore calves.
FAU - Vedovatto, Marcelo
AU  - Vedovatto M
AD  - University of Florida - Range Cattle Research and Education Center, Ona, FL, 
      33865, USA.
FAU - da Silva Pereira, Camila
AU  - da Silva Pereira C
AD  - Faculdade de Medicina Veterinaria e Zootecnia, Universidade Federal de Mato 
      Grosso do Sul, Campo Grande, MS, 79070-900, Brazil.
FAU - Cortada Neto, Ibrahim Miranda
AU  - Cortada Neto IM
AD  - Faculdade de Medicina Veterinaria e Zootecnia, Universidade Federal de Mato 
      Grosso do Sul, Campo Grande, MS, 79070-900, Brazil.
FAU - Moriel, Philipe
AU  - Moriel P
AD  - University of Florida - Range Cattle Research and Education Center, Ona, FL, 
      33865, USA.
FAU - Morais, Maria da Graca
AU  - Morais MDG
AD  - Faculdade de Medicina Veterinaria e Zootecnia, Universidade Federal de Mato 
      Grosso do Sul, Campo Grande, MS, 79070-900, Brazil.
FAU - Franco, Gumercindo Loriano
AU  - Franco GL
AUID- ORCID: 0000-0002-9868-0256
AD  - Faculdade de Medicina Veterinaria e Zootecnia, Universidade Federal de Mato 
      Grosso do Sul, Campo Grande, MS, 79070-900, Brazil. gumercindo.franco@ufms.br.
LA  - eng
GR  - 116/2016/Fundacao de Apoio ao Desenvolvimento do Ensino, Ciencia e Tecnologia do 
      Estado de Mato Grosso do Sul/
PT  - Journal Article
DEP - 20190830
PL  - United States
TA  - Trop Anim Health Prod
JT  - Tropical animal health and production
JID - 1277355
RN  - 0 (Antioxidants)
RN  - 0 (Minerals)
RN  - 0 (Trace Elements)
SB  - IM
MH  - Animals
MH  - Antioxidants/*metabolism
MH  - Cattle/growth & development/immunology/*physiology
MH  - Immune System/*drug effects/immunology
MH  - Injections, Subcutaneous/veterinary
MH  - Minerals/administration & dosage/metabolism
MH  - Trace Elements/administration & dosage/*metabolism
MH  - Weaning
OTO - NOTNLM
OT  - Cattle
OT  - Glutathione peroxidase
OT  - Hemogram
OT  - Superoxide dismutase
OT  - Weight gain
EDAT- 2019/09/01 06:00
MHDA- 2020/08/01 06:00
CRDT- 2019/09/01 06:00
PHST- 2019/05/28 00:00 [received]
PHST- 2019/08/19 00:00 [accepted]
PHST- 2019/09/01 06:00 [pubmed]
PHST- 2020/08/01 06:00 [medline]
PHST- 2019/09/01 06:00 [entrez]
AID - 10.1007/s11250-019-02056-0 [pii]
AID - 10.1007/s11250-019-02056-0 [doi]
PST - ppublish
SO  - Trop Anim Health Prod. 2020 Mar;52(2):881-886. doi: 10.1007/s11250-019-02056-0. 
      Epub 2019 Aug 30.