PMID- 31473542 OWN - NLM STAT- MEDLINE DCOM- 20200219 LR - 20200219 IS - 1095-7103 (Electronic) IS - 0021-9797 (Linking) VI - 556 DP - 2019 Nov 15 TI - Spray-drying water-based assembly of hierarchical and ordered mesoporous silica microparticles with enhanced pore accessibility for efficient bio-adsorption. PG - 529-540 LID - S0021-9797(19)30995-6 [pii] LID - 10.1016/j.jcis.2019.08.084 [doi] AB - The fast and scalable spray-drying-assisted evaporation-induced self-assembly (EISA) synthesis of hierarchically porous SBA-15-type silica microparticles from a water-based system is demonstrated. The SBA-15-type silica microparticles has bowl-like shapes, uniform micro-sizes ( approximately 90 microm), large ordered mesopores ( approximately 9.5 nm), hierarchical meso-/macropores (20-100 nm) and open surfaces. In the synthesis, soft- and hard-templating approaches are combined in a single rapid drying process with a non-ionic tri-block copolymer (F127) and a water-insoluble polymer colloid (Eudragit RS, 120 nm) as the co-templates. The RS polymer colloid plays three important roles. First, the RS nanoparticles can be partially dissolved by in-situ generated ethanol to form RS polymer chains. The RS chains swell and modulate the hydrophilic-hydrophobic balance of F127 micelles to allow the formation of an ordered mesostructure with large mesopore sizes. Without RS, only worm-like mesostructure with much smaller mesopore sizes can be formed. Second, part of the RS nanoparticles plays a role in templating the hierarchical pores distributed throughout the microparticles. Third, part of the RS polymer forms surface "skins" and "bumps", which can be removed by calcination to enable a more open surface structure to overcome the low pore accessibility issue of spray-dried porous microparticles. The obtained materials have high surface areas (315-510 m(2) g(-1)) and large pore volumes (0.64-1.0 cm(3) g(-1)), which are dependent on RS concentration, HCl concentration, silica precursor hydrolysis time and drying temperature. The representative materials are promising for the adsorption of lysozyme. The adsorption occurs at a >three-fold faster rate, in a five-fold larger capacity (an increase from 20 to 100 mg g(-1)) and without pore blockage compared with the adsorption of lysozyme onto spray-dried microparticles of similar physicochemical properties obtained without the use of RS. CI - Copyright (c) 2019 Elsevier Inc. All rights reserved. FAU - Wu, Zhangxiong AU - Wu Z AD - Particle Technology Engineering Laboratory, School of Chemical and Environmental Engineering, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou City, Jiangsu 215123, PR China; Department of Chemical Engineering, Monash University, Clayton Campus, Victoria 3800, Australia. Electronic address: zhangwu@suda.edu.cn. FAU - Waldron, Kathryn AU - Waldron K AD - Department of Chemical Engineering, Monash University, Clayton Campus, Victoria 3800, Australia. FAU - Zhang, Xiangcheng AU - Zhang X AD - Particle Technology Engineering Laboratory, School of Chemical and Environmental Engineering, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou City, Jiangsu 215123, PR China. FAU - Li, Yunqing AU - Li Y AD - Particle Technology Engineering Laboratory, School of Chemical and Environmental Engineering, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou City, Jiangsu 215123, PR China. FAU - Wu, Lei AU - Wu L AD - Particle Technology Engineering Laboratory, School of Chemical and Environmental Engineering, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou City, Jiangsu 215123, PR China. FAU - Wu, Winston Duo AU - Wu WD AD - Particle Technology Engineering Laboratory, School of Chemical and Environmental Engineering, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou City, Jiangsu 215123, PR China. FAU - Chen, Xiao Dong AU - Chen XD AD - Particle Technology Engineering Laboratory, School of Chemical and Environmental Engineering, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou City, Jiangsu 215123, PR China. FAU - Zhao, Dongyuan AU - Zhao D AD - Department of Chemistry and Laboratory of Advanced Materials, Fudan University, Shanghai, 200433, PR China; Department of Chemical Engineering, Monash University, Clayton Campus, Victoria 3800, Australia. FAU - Selomulya, Cordelia AU - Selomulya C AD - Department of Chemical Engineering, Monash University, Clayton Campus, Victoria 3800, Australia. Electronic address: cordelia.selomulya@monash.edu. LA - eng PT - Journal Article DEP - 20190824 PL - United States TA - J Colloid Interface Sci JT - Journal of colloid and interface science JID - 0043125 RN - 0 (Acrylic Resins) RN - 0 (Avian Proteins) RN - 0 (Micelles) RN - 0 (Polyethylenes) RN - 0 (Polypropylenes) RN - 0 (SBA-15) RN - 33434-24-1 (Eudragit RS) RN - 7631-86-9 (Silicon Dioxide) RN - 9038-95-3 (UCON 50-HB-5100) RN - EC 3.2.1.17 (Muramidase) SB - IM MH - Acrylic Resins/*chemistry MH - Adsorption MH - Animals MH - Avian Proteins/chemistry MH - Chickens MH - Desiccation MH - Hydrophobic and Hydrophilic Interactions MH - *Micelles MH - Muramidase/chemistry MH - Nanoparticles/*chemistry MH - Polyethylenes/*chemistry MH - Polypropylenes/*chemistry MH - Porosity MH - Silicon Dioxide/*chemistry OTO - NOTNLM OT - Bio-adsorption OT - Hierarchical structure OT - Particle processing OT - Porous silica OT - Spray drying EDAT- 2019/09/02 06:00 MHDA- 2020/02/20 06:00 CRDT- 2019/09/02 06:00 PHST- 2019/05/28 00:00 [received] PHST- 2019/08/22 00:00 [revised] PHST- 2019/08/23 00:00 [accepted] PHST- 2019/09/02 06:00 [pubmed] PHST- 2020/02/20 06:00 [medline] PHST- 2019/09/02 06:00 [entrez] AID - S0021-9797(19)30995-6 [pii] AID - 10.1016/j.jcis.2019.08.084 [doi] PST - ppublish SO - J Colloid Interface Sci. 2019 Nov 15;556:529-540. doi: 10.1016/j.jcis.2019.08.084. Epub 2019 Aug 24.