PMID- 31473949 OWN - NLM STAT- MEDLINE DCOM- 20200110 LR - 20200110 IS - 1573-3432 (Electronic) IS - 0162-3257 (Linking) VI - 49 IP - 11 DP - 2019 Nov TI - Patterns of Cerebellar Connectivity with Intrinsic Connectivity Networks in Autism Spectrum Disorders. PG - 4498-4514 LID - 10.1007/s10803-019-04168-w [doi] AB - There is growing evidence of altered connectivity in autism spectrum disorders (ASD) between the cerebellum and cortex. Three intrinsic connectivity networks (ICNs) are especially important to cognitive processing in ASD: the default mode network (DMN), executive control network (ECN), and salience networks (SNs). The goal of this study was to compare resting-state functional connectivity between the cerebellum and the DMN, ECN, and SN in ASD and typically developing children (n = 74, ages 7-12 years). Children with ASD showed stronger connectivity between the ventral DMN and left cerebellar lobules I-IV. No meaningful relationships were observed between ICN-cerebellar functional connectivity and ASD symptoms. These results suggest that the cerebellum contributes to altered network connectivity in ASD. FAU - Bednarz, Haley M AU - Bednarz HM AD - Department of Psychology, University of Alabama at Birmingham, CIRC 235G, 1719 6th Ave South, Birmingham, AL, 35294-0021, USA. FAU - Kana, Rajesh K AU - Kana RK AD - Department of Psychology, University of Alabama at Birmingham, CIRC 235G, 1719 6th Ave South, Birmingham, AL, 35294-0021, USA. rkana@uab.edu. LA - eng PT - Journal Article PL - United States TA - J Autism Dev Disord JT - Journal of autism and developmental disorders JID - 7904301 SB - IM MH - Autism Spectrum Disorder/*physiopathology MH - Case-Control Studies MH - Cerebellum/*physiopathology MH - Cerebral Cortex/*physiopathology MH - Child MH - Executive Function MH - Female MH - Humans MH - Magnetic Resonance Imaging MH - Male MH - Motivation MH - Neural Pathways/physiopathology MH - Neuroimaging OTO - NOTNLM OT - Autism OT - Cerebellum OT - Default mode OT - Executive OT - Salience EDAT- 2019/09/02 06:00 MHDA- 2020/01/11 06:00 CRDT- 2019/09/02 06:00 PHST- 2019/09/02 06:00 [pubmed] PHST- 2020/01/11 06:00 [medline] PHST- 2019/09/02 06:00 [entrez] AID - 10.1007/s10803-019-04168-w [pii] AID - 10.1007/s10803-019-04168-w [doi] PST - ppublish SO - J Autism Dev Disord. 2019 Nov;49(11):4498-4514. doi: 10.1007/s10803-019-04168-w.