PMID- 31479006
OWN - NLM
STAT- MEDLINE
DCOM- 20200903
LR  - 20210211
IS  - 1530-0315 (Electronic)
IS  - 0195-9131 (Linking)
VI  - 52
IP  - 2
DP  - 2020 Feb
TI  - Individual Response to Standardized Exercise: Total and Abdominal Adipose Tissue.
PG  - 490-497
LID - 10.1249/MSS.0000000000002140 [doi]
AB  - PURPOSE: (1) Determine the effect of exercise amount and intensity on the 
      proportion of individuals for whom the adipose tissue (AT) response is above the 
      minimal clinically important difference (MCID); and (2) Examine whether 
      clinically meaningful anthropometric changes reflect individual AT responses 
      above the MCID. METHODS: Men (n = 41) and women (n = 62) (52.7 +/- 7.6 yr) were 
      randomized to control (n = 20); low amount low intensity (n = 24); high amount 
      low intensity (n = 30); and high amount high intensity (n = 29) treadmill 
      exercise for 24 wk. The AT changes were measured by MRI. 90% confidence intervals 
      for each individual's observed response were calculated as the observed score 
      +/-1.64 x TE (technical error of measurement). RESULTS: For visceral AT, HAHI and 
      HALI had a greater proportion of individuals whose AT change and 90% confidence 
      interval were beyond the MCID compared to controls (P < 0.006). For all other AT 
      depots, all exercise groups had significantly more individuals whose changes were 
      beyond the MCID compared with controls. Of those who achieved a waist 
      circumference or body weight reduction >/= the MCID, 76% to 93% achieved abdominal, 
      abdominal subcutaneous, and visceral AT changes >/= the MCID. CONCLUSIONS: 
      Increasing exercise amount and/or intensity may increase the proportion of 
      individuals who achieve clinically meaningful visceral AT reductions. Waist 
      circumference or body weight changes beyond a clinically meaningful threshold are 
      predictive of clinically meaningful abdominal adiposity changes.
FAU - Brennan, Andrea M
AU  - Brennan AM
AD  - School of Kinesiology and Health Studies, Queen's University, Kingston, ON, 
      CANADA.
FAU - Day, Andrew G
AU  - Day AG
FAU - Cowan, Theresa E
AU  - Cowan TE
AD  - School of Kinesiology and Health Studies, Queen's University, Kingston, ON, 
      CANADA.
FAU - Clarke, Gregory J
AU  - Clarke GJ
AD  - School of Kinesiology and Health Studies, Queen's University, Kingston, ON, 
      CANADA.
FAU - Lamarche, Benoit
AU  - Lamarche B
AD  - Institute of Nutraceuticals and Functional Foods, Laval University, Quebec City, 
      Quebec, CANADA.
FAU - Ross, Robert
AU  - Ross R
LA  - eng
GR  - OHN-63277/CIHR/Canada
PT  - Journal Article
PT  - Randomized Controlled Trial
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Med Sci Sports Exerc
JT  - Medicine and science in sports and exercise
JID - 8005433
SB  - IM
MH  - Abdominal Fat/*anatomy & histology/diagnostic imaging
MH  - Adiposity/*physiology
MH  - Energy Intake
MH  - Exercise Therapy/*methods
MH  - Female
MH  - Humans
MH  - Magnetic Resonance Imaging
MH  - Male
MH  - Middle Aged
MH  - Minimal Clinically Important Difference
MH  - Obesity, Abdominal/*physiopathology/*therapy
MH  - Physical Conditioning, Human/*methods
MH  - Waist Circumference
MH  - Weight Loss
EDAT- 2019/09/04 06:00
MHDA- 2020/09/04 06:00
CRDT- 2019/09/04 06:00
PHST- 2019/09/04 06:00 [pubmed]
PHST- 2020/09/04 06:00 [medline]
PHST- 2019/09/04 06:00 [entrez]
AID - 00005768-202002000-00026 [pii]
AID - 10.1249/MSS.0000000000002140 [doi]
PST - ppublish
SO  - Med Sci Sports Exerc. 2020 Feb;52(2):490-497. doi: 10.1249/MSS.0000000000002140.