PMID- 31480306
OWN - NLM
STAT- MEDLINE
DCOM- 20200116
LR  - 20200309
IS  - 1660-4601 (Electronic)
IS  - 1661-7827 (Print)
IS  - 1660-4601 (Linking)
VI  - 16
IP  - 17
DP  - 2019 Aug 30
TI  - Remission of Type 2 Diabetes Mellitus after Bariatric Surgery: Fact or Fiction?
LID - 10.3390/ijerph16173171 [doi]
LID - 3171
AB  - Although type 2 diabetes mellitus (T2DM) has been traditionally viewed as an 
      intractable chronic medical condition, accumulating evidence points towards the 
      notion that a complete remission of T2DM is feasible following a choice of 
      medical and/or surgical interventions. This has been paralleled by increasing 
      interest in the establishment of a universal definition for T2DM remission which, 
      under given circumstances, could be considered equivalent to a "cure". The 
      efficacy of bariatric surgery in particular for achieving glycemic control has 
      highlighted surgery as a candidate curative intervention for T2DM. Herein, 
      available evidence regarding available surgical modalities and the mechanisms 
      that drive metabolic amelioration after bariatric surgery are reviewed. 
      Furthermore, reports from observational and randomized studies with regard to 
      T2DM remission are reviewed, along with concepts relevant to the variety of 
      definitions used for T2DM remission and other potential sources of discrepancy in 
      success rates among different studies.
FAU - Tsilingiris, Dimitrios
AU  - Tsilingiris D
AD  - First Department of Propaedeutic Internal Medicine and Diabetes Center, Medical 
      School, National and Kapodistrian University of Athens, Laiko General Hospital, 
      Athens 11527, Greece.
FAU - Koliaki, Chrysi
AU  - Koliaki C
AD  - First Department of Propaedeutic Internal Medicine and Diabetes Center, Medical 
      School, National and Kapodistrian University of Athens, Laiko General Hospital, 
      Athens 11527, Greece.
FAU - Kokkinos, Alexander
AU  - Kokkinos A
AD  - First Department of Propaedeutic Internal Medicine and Diabetes Center, Medical 
      School, National and Kapodistrian University of Athens, Laiko General Hospital, 
      Athens 11527, Greece. akokkinos@med.uoa.gr.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20190830
PL  - Switzerland
TA  - Int J Environ Res Public Health
JT  - International journal of environmental research and public health
JID - 101238455
SB  - IM
MH  - Bariatric Surgery/*statistics & numerical data
MH  - Diabetes Mellitus, Type 2/*surgery
MH  - Humans
MH  - Remission Induction
MH  - Treatment Outcome
PMC - PMC6747427
OTO - NOTNLM
OT  - bariatric surgery
OT  - diabetes remission
OT  - metabolic surgery
OT  - type 2 diabetes
COIS- The authors declare no conflict of interest.
EDAT- 2019/09/05 06:00
MHDA- 2020/01/17 06:00
PMCR- 2019/09/01
CRDT- 2019/09/05 06:00
PHST- 2019/07/13 00:00 [received]
PHST- 2019/08/20 00:00 [revised]
PHST- 2019/08/29 00:00 [accepted]
PHST- 2019/09/05 06:00 [entrez]
PHST- 2019/09/05 06:00 [pubmed]
PHST- 2020/01/17 06:00 [medline]
PHST- 2019/09/01 00:00 [pmc-release]
AID - ijerph16173171 [pii]
AID - ijerph-16-03171 [pii]
AID - 10.3390/ijerph16173171 [doi]
PST - epublish
SO  - Int J Environ Res Public Health. 2019 Aug 30;16(17):3171. doi: 
      10.3390/ijerph16173171.