PMID- 31482216
OWN - NLM
STAT- MEDLINE
DCOM- 20201026
LR  - 20231205
IS  - 1615-2573 (Electronic)
IS  - 0910-8327 (Linking)
VI  - 35
IP  - 3
DP  - 2020 Mar
TI  - Spontaneous coronary collateral recruitment in patients with recurrent ST 
      elevation myocardial infarction (STEMI).
PG  - 291-296
LID - 10.1007/s00380-019-01493-z [doi]
AB  - The spontaneous recruitment of acute coronary collaterals in the setting of an ST 
      elevation myocardial infarction (STEMI) is seen frequently in those patients 
      undergoing primary percutaneous coronary intervention (pPCI) and is associated 
      with improved clinical outcomes. However, it is unknown whether in patients who 
      present with a recurrent STEMI, the degree of collateral recruitment remains the 
      same as in the index procedure. We reviewed all patients presenting to our 
      tertiary centre with a STEMI undergoing primary or rescue percutaneous coronary 
      intervention (PCI) from July 2010 until December 2018. We identified patients who 
      presented with a recurrent STEMI following their index procedure. We defined 
      patients with poor collateral recruitment as Rentrop grade 0 or 1, whilst 
      patients with robust collateral recruitment as Rentrop grade 2 or 3. Of the 1795 
      patients who were identified, there were 27 cases in 25 patients who presented 
      with a repeat STEMI following their index procedure. The median time between 
      cases was 12.8 days (IQR 2.3-589.5 days). Compared to the index case, there was 
      no statistically significant difference in the degree of collateral recruitment 
      in recurrent presentations (Z = - 0.378, p = 0.70). In those patients presenting 
      more than 6 months following the index procedure, the median time between cases 
      was 654.5 days (IQR 479.5-1151.9). There was no difference in the degree of 
      collateral recruitment in recurrent presentations (Z = 0.000, p = 1.0). Cases 
      which had poorer collateral recruitment in recurrent presentations were less 
      likely to be current smokers (0% vs 50%, p < 0.001) and less likely to have 
      diabetes (0% vs 27.3%, p < 0.05) The recruitment of spontaneous coronary 
      collaterals remains constant in recurrent STEMI presentations suggesting an 
      innate biological process rather than merely a manifestation of alteration of 
      haemodynamic blood flow. Further investigations to identify these processes is 
      required.
FAU - Allahwala, Usaid K
AU  - Allahwala UK
AUID- ORCID: 0000-0001-7178-4744
AD  - Department of Cardiology, Royal North Shore Hospital, Reserve Rd, St. Leonards, 
      Sydney, 2065, Australia. usaid.allahwala@gmail.com.
AD  - The University of Sydney, Sydney, Australia. usaid.allahwala@gmail.com.
FAU - Weaver, James C
AU  - Weaver JC
AD  - Department of Cardiology, Royal Prince Alfred Hospital, Sydney, Australia.
AD  - The University of New South Wales, Sydney, NSW, Australia.
FAU - Bhindi, Ravinay
AU  - Bhindi R
AD  - Department of Cardiology, Royal North Shore Hospital, Reserve Rd, St. Leonards, 
      Sydney, 2065, Australia.
AD  - The University of Sydney, Sydney, Australia.
LA  - eng
PT  - Journal Article
DEP - 20190903
PL  - Japan
TA  - Heart Vessels
JT  - Heart and vessels
JID - 8511258
SB  - IM
MH  - Acute Coronary Syndrome/diagnostic imaging/physiopathology/*therapy
MH  - Aged
MH  - *Collateral Circulation
MH  - *Coronary Circulation
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Percutaneous Coronary Intervention/*adverse effects
MH  - Recovery of Function
MH  - Recurrence
MH  - Retrospective Studies
MH  - Risk Factors
MH  - ST Elevation Myocardial Infarction/diagnostic imaging/physiopathology/*therapy
MH  - Time Factors
MH  - Treatment Outcome
OTO - NOTNLM
OT  - Acute coronary syndrome
OT  - Collaterals
OT  - Coronary collaterals
OT  - Rentrop
OT  - STEMI
EDAT- 2019/09/05 06:00
MHDA- 2020/10/27 06:00
CRDT- 2019/09/05 06:00
PHST- 2019/06/13 00:00 [received]
PHST- 2019/08/23 00:00 [accepted]
PHST- 2019/09/05 06:00 [pubmed]
PHST- 2020/10/27 06:00 [medline]
PHST- 2019/09/05 06:00 [entrez]
AID - 10.1007/s00380-019-01493-z [pii]
AID - 10.1007/s00380-019-01493-z [doi]
PST - ppublish
SO  - Heart Vessels. 2020 Mar;35(3):291-296. doi: 10.1007/s00380-019-01493-z. Epub 2019 
      Sep 3.