PMID- 31489272
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20201001
IS  - 2168-8184 (Print)
IS  - 2168-8184 (Electronic)
IS  - 2168-8184 (Linking)
VI  - 11
IP  - 8
DP  - 2019 Aug 21
TI  - Sudden-onset Hypoglycemia Following Fluid Replacement in a Patient with 
      Dapagliflozin-induced Diabetic Ketoacidosis Without Prior Insulin Use: Case 
      Report.
PG  - e5448
LID - 10.7759/cureus.5448 [doi]
LID - e5448
AB  - Euglycemic diabetic ketoacidosis (DKA) is a known complication of sodium-glucose 
      co-transporter 2 (SGLT-2) inhibitors that have been reported in the literature. 
      The prevalence of this side effect is growing and the exact mechanism of action 
      on why this happens is unknown. Hypoglycemia events are very rare in diabetic 
      patients using SGLT-2 inhibitors and/or metformin when they have normal kidney 
      function. We report a novel complication of hypoglycemia that occurred during the 
      course of treatment of SGLT2 inhibitor-induced DKA in a patient with type 2 
      diabetes mellitus (T2DM) on the dapagliflozin-metformin combination.
FAU - Elshimy, Ghada
AU  - Elshimy G
AD  - Endocrinology, Diabetes and Metabolism, University of Arizona College of 
      Medicine-Phoenix, Phoenix, USA.
FAU - Correa, Ricardo
AU  - Correa R
AD  - Endocrinology, Diabetes and Metabolism, University of Arizona College of 
      Medicine-Phoenix, Phoenix, USA.
LA  - eng
PT  - Case Reports
DEP - 20190821
PL  - United States
TA  - Cureus
JT  - Cureus
JID - 101596737
PMC - PMC6713257
OTO - NOTNLM
OT  - diabetic ketoacidosis
OT  - hypoglycemia
OT  - metformin
OT  - sodium-glucose co transporter-2 (sglt2) inhibitors
COIS- The authors have declared that no competing interests exist.
EDAT- 2019/09/07 06:00
MHDA- 2019/09/07 06:01
PMCR- 2019/08/21
CRDT- 2019/09/07 06:00
PHST- 2019/09/07 06:00 [entrez]
PHST- 2019/09/07 06:00 [pubmed]
PHST- 2019/09/07 06:01 [medline]
PHST- 2019/08/21 00:00 [pmc-release]
AID - 10.7759/cureus.5448 [doi]
PST - epublish
SO  - Cureus. 2019 Aug 21;11(8):e5448. doi: 10.7759/cureus.5448.