PMID- 31493400
OWN - NLM
STAT- MEDLINE
DCOM- 20200327
LR  - 20200327
IS  - 1879-1891 (Electronic)
IS  - 0002-9394 (Linking)
VI  - 208
DP  - 2019 Dec
TI  - Incidence of Intraoperative and Early Postoperative Adverse Events in a Large 
      Cohort of Consecutive Refractive Lens Exchange Procedures.
PG  - 406-414
LID - S0002-9394(19)30446-5 [pii]
LID - 10.1016/j.ajo.2019.08.025 [doi]
AB  - PURPOSE: To evaluate the incidence of adverse events (AEs) in patients who 
      underwent refractive lens exchange. DESIGN: Retrospective case series. METHODS: 
      Setting: Private refractive surgery clinics. Patients/Study Population: Patients 
      who underwent refractive lens exchange between July 1, 2014, and June 30, 2016. 
      Intervention/Observation Procedures: All AEs recorded in the electronic medical 
      record were extracted and retrospectively reviewed. The total incidence of AEs 
      and serious AEs was calculated. Loss of 2 or more lines of corrected distance 
      visual acuity (CDVA) was calculated for the entire cohort of patients that 
      attended a minimum of 3 months follow-up. MAIN OUTCOME MEASURES: AEs. RESULTS: 
      The total number of patients included was 10,206 (18,689 eyes). A multifocal 
      intraocular lens (IOL) was implanted in 84.3% of eyes; 15.7% of eyes received a 
      monofocal IOL. A total of 1164 AEs were recorded (1112 eyes of 1039 patients, 
      incidence 6.0% of eyes, 1:17 eyes). The most common AE was posterior capsular 
      opacification (PCO; 748 eyes, incidence 4.0%). Of all AEs, 171 events (occurring 
      in 165 eyes of 151 patients, incidence 0.9%, 1:113 eyes) were classified as 
      serious, potentially sight threatening. Loss of 2 or more lines of CDVA was 0.56% 
      when excluding eyes where the loss of CDVA was due to PCO; the majority of these 
      were due to macular causes. CONCLUSION: The incidence of sight-threatening AEs 
      and significant loss of CDVA in elective refractive lens exchange surgery was 
      low. Other than PCO, postoperative macular issues were the most common cause of 
      vision loss in this cohort.
CI  - Copyright (c) 2019 Elsevier Inc. All rights reserved.
FAU - Schallhorn, Julie M
AU  - Schallhorn JM
AD  - Department of Ophthalmology, University of California, San Francisco, San 
      Francisco, California, USA; F.I. Proctor Foundation, University of California, 
      San Francisco, San Francisco, California, USA. Electronic address: 
      Julie.schallhorn@ucsf.edu.
FAU - Schallhorn, Steven C
AU  - Schallhorn SC
AD  - Department of Ophthalmology, University of California, San Francisco, San 
      Francisco, California, USA; Carl Zeiss, Meditec, Dublin, California, USA; Optical 
      Express, Glasgow, United Kingdom.
FAU - Teenan, David
AU  - Teenan D
AD  - Optical Express, Glasgow, United Kingdom.
FAU - Hannan, Stephen J
AU  - Hannan SJ
AD  - Optical Express, Glasgow, United Kingdom.
FAU - Pelouskova, Martina
AU  - Pelouskova M
AD  - Optical Express, Glasgow, United Kingdom.
FAU - Venter, Jan A
AU  - Venter JA
AD  - Optical Express, Glasgow, United Kingdom.
LA  - eng
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, Non-U.S. Gov't
DEP - 20190904
PL  - United States
TA  - Am J Ophthalmol
JT  - American journal of ophthalmology
JID - 0370500
SB  - IM
MH  - Adult
MH  - Aged
MH  - Device Removal
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - Incidence
MH  - Intraoperative Complications/*epidemiology
MH  - Lens Implantation, Intraocular/*statistics & numerical data
MH  - Lenses, Intraocular
MH  - Male
MH  - Middle Aged
MH  - Multifocal Intraocular Lenses
MH  - *Phacoemulsification
MH  - Postoperative Complications/*epidemiology
MH  - Refraction, Ocular/physiology
MH  - Reoperation
MH  - Retrospective Studies
MH  - Visual Acuity/physiology
EDAT- 2019/09/08 06:00
MHDA- 2020/03/28 06:00
CRDT- 2019/09/08 06:00
PHST- 2019/03/12 00:00 [received]
PHST- 2019/08/23 00:00 [revised]
PHST- 2019/08/26 00:00 [accepted]
PHST- 2019/09/08 06:00 [pubmed]
PHST- 2020/03/28 06:00 [medline]
PHST- 2019/09/08 06:00 [entrez]
AID - S0002-9394(19)30446-5 [pii]
AID - 10.1016/j.ajo.2019.08.025 [doi]
PST - ppublish
SO  - Am J Ophthalmol. 2019 Dec;208:406-414. doi: 10.1016/j.ajo.2019.08.025. Epub 2019 
      Sep 4.