PMID- 31513736
OWN - NLM
STAT- MEDLINE
DCOM- 20200608
LR  - 20200608
IS  - 2042-6984 (Electronic)
IS  - 2042-6976 (Linking)
VI  - 9
IP  - 11
DP  - 2019 Nov
TI  - Associations among air pollutants, grass pollens, and daily number of grass 
      pollen allergen-positive patients: a longitudinal study from 2012 to 2016.
PG  - 1297-1303
LID - 10.1002/alr.22389 [doi]
AB  - BACKGROUND: Grass pollen is the most prevalent sensitizing aeroallergen to cause 
      respiratory allergies in northern China. Air pollutants have a substantial effect 
      on respiratory health and some pollens. This study aimed to investigate 
      relationships among airborne grass pollen, air pollutants and allergic diseases, 
      in order to determine their effects on patients with grass pollen allergies in 
      Beijing, China, during the period from 2013 to 2016. METHODS: Data regarding 
      autumnal grass pollens and air pollutants measured in Beijing from 2012 to 2016 
      were obtained from local governmental agencies. Patient data regarding specific 
      immunoglobulin E (IgE) analyses from 2013 to 2016 were obtained from the 
      Department of Allergy in Beijing Tongren Hospital. Spearman's rank correlation 
      analysis was used to assess associations between the daily number of grass pollen 
      allergen-positive patients and the following parameters: 3 clinically-relevant 
      grass pollen genera (Artemisia, Humulus, and Chenopodium) and inhalable 
      pollutants. RESULTS: Correlation analysis indicated that the daily number of 
      grass pollen-positive patients was significantly associated with the peak period 
      of grass pollens, as well as pollutants SO(2) and NOx. Moreover, concentrations 
      of air pollutants (eg, ozone, oxides of nitrogen [NO(x) ], and SO(2) ) were 
      consistently and significantly associated with concentrations of grass pollens; 
      particulate matter 2.5 microm in diameter was negatively associated with Artemisia 
      and Chenopodium pollens. CONCLUSION: Grass pollens exhibited substantial impact 
      on allergic disease morbidity. Air pollutants impacted allergic disease and grass 
      pollen. Thus, public health and clinical approaches to anticipate and reduce 
      allergic disease morbidity from pollen and pollutants are needed.
CI  - (c) 2019 ARS-AAOA, LLC.
FAU - Ouyang, Yuhui
AU  - Ouyang Y
AD  - Department of Otolaryngology-Head and Neck Surgery and Department of Allergy, 
      Beijing Tongren Hospital, Affiliated to the Capital University of Medical 
      Science, Beijing, China.
AD  - Beijing Key Laboratory of Nasal Diseases, Beijing Institute of Otolaryngology, 
      Beijing, China.
FAU - Yin, Zhaoyin
AU  - Yin Z
AD  - Beijing Weather Information Service, Beijing, China.
FAU - Li, Ying
AU  - Li Y
AD  - Beijing Key Laboratory of Nasal Diseases, Beijing Institute of Otolaryngology, 
      Beijing, China.
FAU - Fan, Erzhong
AU  - Fan E
AD  - Beijing Key Laboratory of Nasal Diseases, Beijing Institute of Otolaryngology, 
      Beijing, China.
FAU - Zhang, Luo
AU  - Zhang L
AUID- ORCID: 0000-0002-0910-9884
AD  - Department of Otolaryngology-Head and Neck Surgery and Department of Allergy, 
      Beijing Tongren Hospital, Affiliated to the Capital University of Medical 
      Science, Beijing, China.
AD  - Beijing Key Laboratory of Nasal Diseases, Beijing Institute of Otolaryngology, 
      Beijing, China.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20190912
PL  - United States
TA  - Int Forum Allergy Rhinol
JT  - International forum of allergy & rhinology
JID - 101550261
RN  - 0 (Air Pollutants)
RN  - 0 (Allergens)
RN  - 0 (Particulate Matter)
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Air Pollutants/adverse effects/*analysis
MH  - Allergens/immunology
MH  - Artemisia
MH  - Chenopodium
MH  - Child
MH  - Child, Preschool
MH  - China/epidemiology
MH  - Female
MH  - Humans
MH  - Humulus
MH  - Immunoglobulin E/blood
MH  - Longitudinal Studies
MH  - Male
MH  - Middle Aged
MH  - Particulate Matter/*analysis
MH  - Pollen/*immunology
MH  - Respiratory Hypersensitivity/diagnosis/*epidemiology
MH  - Rhinitis, Allergic, Seasonal/diagnosis/*epidemiology
MH  - Young Adult
OTO - NOTNLM
OT  - Artemisia
OT  - Chenopodium
OT  - China
OT  - Humulus
OT  - Poaceae
OT  - immunoglobulin E
OT  - ozone
OT  - particulate matter
OT  - respiratory hypersensitivity
OT  - sulfur dioxide
EDAT- 2019/09/13 06:00
MHDA- 2020/06/09 06:00
CRDT- 2019/09/13 06:00
PHST- 2019/02/19 00:00 [received]
PHST- 2019/05/30 00:00 [revised]
PHST- 2019/07/04 00:00 [accepted]
PHST- 2019/09/13 06:00 [pubmed]
PHST- 2020/06/09 06:00 [medline]
PHST- 2019/09/13 06:00 [entrez]
AID - 10.1002/alr.22389 [doi]
PST - ppublish
SO  - Int Forum Allergy Rhinol. 2019 Nov;9(11):1297-1303. doi: 10.1002/alr.22389. Epub 
      2019 Sep 12.