PMID- 31514898
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20190930
LR  - 20190930
IS  - 1873-3573 (Electronic)
IS  - 0039-9140 (Linking)
VI  - 206
DP  - 2020 Jan 1
TI  - Determination of heterocyclic aromatic amines in ashes from biomass burning by 
      UHPLC-MS/MS after ultrasound-assisted dispersive solid-liquid microextraction.
PG  - 120182
LID - S0039-9140(19)30815-X [pii]
LID - 10.1016/j.talanta.2019.120182 [doi]
AB  - A simple, rapid and efficient methodology was developed for the extraction and 
      determination of heterocyclic aromatic amines (HAAs) in cigarette and forest fire 
      ash samples based on a novel Ultrasound-Assisted Dispersive Solid-liquid 
      Microextraction (UA-DSLME) coupled to polyurethane foam (PUF) mini-column as a 
      clean-up strategy and on-line determination by liquid chromatography-tandem mass 
      spectrometry (LC-MS/MS). The optimal working conditions were found by (i) 
      application of two-level full factorial designs and (ii) implementation of a 
      response surface methodology based on the second-order design as central 
      composite designs. Under optimal experimental conditions, good linearity was 
      obtained for concentrations ranging from 8.3 to 500 ng g(-1), with correlation 
      coefficients (r(2)) varying from 0.995 to 0.999 for all HAAs investigated. The 
      limits of detection and quantification resulted to be between 2.1 and 
      10.7 ng g(-1) and 8.3-16.9 ng g(-1), respectively. The recoveries from 92.2 to 
      100.6% were reached and the relative standard deviations (RSDs) were lower than 
      9.2%. The developed method was successfully applied to the determination of HAAs 
      in ashes generated by cigarette and forest fire combustion.
CI  - Copyright (c) 2019 Elsevier B.V. All rights reserved.
FAU - Guinez, Maria
AU  - Guinez M
AD  - Comision Nacional de Energia Atomica (CNEA), Gerencia Quimica, Av. Gral. Paz 
      1499, B1650KNA-San Martin, Pcia., Buenos Aires, Argentina. Electronic address: 
      maevangelinaguinez@gmail.com.
FAU - Canales, Romina
AU  - Canales R
AD  - Instituto de Quimica de San Luis (CCT-San Luis), Laboratorio de Espectrometria de 
      Masas, Bloque III, Ejercito de Los Andes 950, San Luis, CP5700, Argentina.
FAU - Talio, Carolina
AU  - Talio C
AD  - Instituto de Quimica de San Luis (CCT-San Luis), Laboratorio de Espectrometria de 
      Masas, Bloque III, Ejercito de Los Andes 950, San Luis, CP5700, Argentina.
FAU - Gomez, Dario
AU  - Gomez D
AD  - Comision Nacional de Energia Atomica (CNEA), Gerencia Quimica, Av. Gral. Paz 
      1499, B1650KNA-San Martin, Pcia., Buenos Aires, Argentina.
FAU - Smichowski, Patricia
AU  - Smichowski P
AD  - Comision Nacional de Energia Atomica (CNEA), Gerencia Quimica, Av. Gral. Paz 
      1499, B1650KNA-San Martin, Pcia., Buenos Aires, Argentina; Consejo Nacional de 
      Investigaciones Cientificas y Tecnicas (CONICET), Godoy Cruz 2290, C1425FQB, 
      Buenos Aires, Argentina. Electronic address: smichows@cnea.gov.ar.
LA  - eng
PT  - Journal Article
DEP - 20190726
PL  - Netherlands
TA  - Talanta
JT  - Talanta
JID - 2984816R
SB  - IM
OTO - NOTNLM
OT  - Biomass burning samples
OT  - Heterocyclic aromatic amines
OT  - Liquid chromatography-tandem mass spectrometry
OT  - Response surface methodology
OT  - Ultrasound-assisted dispersive solid-liquid microextraction
EDAT- 2019/09/14 06:00
MHDA- 2019/09/14 06:01
CRDT- 2019/09/14 06:00
PHST- 2019/03/19 00:00 [received]
PHST- 2019/07/23 00:00 [revised]
PHST- 2019/07/25 00:00 [accepted]
PHST- 2019/09/14 06:00 [entrez]
PHST- 2019/09/14 06:00 [pubmed]
PHST- 2019/09/14 06:01 [medline]
AID - S0039-9140(19)30815-X [pii]
AID - 10.1016/j.talanta.2019.120182 [doi]
PST - ppublish
SO  - Talanta. 2020 Jan 1;206:120182. doi: 10.1016/j.talanta.2019.120182. Epub 2019 Jul 
      26.