PMID- 31516118
OWN - NLM
STAT- MEDLINE
DCOM- 20200318
LR  - 20210110
IS  - 1476-1645 (Electronic)
IS  - 0002-9637 (Print)
IS  - 0002-9637 (Linking)
VI  - 101
IP  - 5
DP  - 2019 Nov
TI  - Case Report: Paracoccidioidomycosis in Solid Organ Transplantation: Disseminated 
      Disease in a Liver Recipient and Literature Review.
PG  - 1100-1106
LID - 10.4269/ajtmh.18-1008 [doi]
AB  - Paracoccidioidomycosis (PCM) is an endemic systemic mycosis that is of great 
      importance in Latin America. Its occurrence in solid organ transplantation (SOT) 
      is rare, but with high mortality rate. In this report, we describe a case of PCM 
      in a liver transplant recipient 19 months after transplantation. The patient 
      presented with multiple skin abscesses, arthritis, osteolytic lesions, and 
      pulmonary and adrenal involvement. Despite the presence of disseminated disease 
      and the patient's immunosuppressed condition, the patient responded well to 
      prolonged antifungal treatment with no sequelae, thus suggesting that early 
      diagnosis and correct treatment may lead to favorable outcomes in SOT recipients 
      with PCM.
FAU - Pecanha-Pietrobom, Paula M
AU  - Pecanha-Pietrobom PM
AD  - Division of Infectious Diseases, Department of Medicine, Escola Paulista de 
      Medicina, Universidade Federal de Sao Paulo, Sao Paulo, Brazil.
FAU - Falqueto, Aloisio
AU  - Falqueto A
AD  - Infectious Diseases Unit, Hospital Universitario Cassiano Antonio Moraes, 
      Universidade Federal do Espirito Santo, Vitoria, Brazil.
FAU - Rodrigues Gandarella, Anna Danielle
AU  - Rodrigues Gandarella AD
AD  - Infectious Diseases Unit, Hospital Universitario Cassiano Antonio Moraes, 
      Universidade Federal do Espirito Santo, Vitoria, Brazil.
FAU - Moyzes, Julia Vieira
AU  - Moyzes JV
AD  - Infectious Diseases Unit, Hospital Universitario Cassiano Antonio Moraes, 
      Universidade Federal do Espirito Santo, Vitoria, Brazil.
FAU - Rangel, Karoline Almeida
AU  - Rangel KA
AD  - Infectious Diseases Unit, Hospital Universitario Cassiano Antonio Moraes, 
      Universidade Federal do Espirito Santo, Vitoria, Brazil.
FAU - Miranda, Leticia Balarini
AU  - Miranda LB
AD  - Infectious Diseases Unit, Hospital Universitario Cassiano Antonio Moraes, 
      Universidade Federal do Espirito Santo, Vitoria, Brazil.
FAU - Hemerly, Matheus Compart
AU  - Hemerly MC
AD  - Infectious Diseases Unit, Hospital Universitario Cassiano Antonio Moraes, 
      Universidade Federal do Espirito Santo, Vitoria, Brazil.
FAU - Careta, Renata Scarpa
AU  - Careta RS
AD  - Department of Pathology, Hospital Universitario Cassiano Antonio Moraes, 
      Universidade Federal do Espirito Santo, Vitoria, Brazil.
FAU - Pecanha, Paulo Mendes
AU  - Pecanha PM
AD  - Infectious Diseases Unit, Hospital Universitario Cassiano Antonio Moraes, 
      Universidade Federal do Espirito Santo, Vitoria, Brazil.
LA  - eng
PT  - Case Reports
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Am J Trop Med Hyg
JT  - The American journal of tropical medicine and hygiene
JID - 0370507
RN  - 0 (Anti-Bacterial Agents)
RN  - 0 (Antifungal Agents)
RN  - 0 (liposomal amphotericin B)
RN  - 7XU7A7DROE (Amphotericin B)
RN  - 8064-90-2 (Trimethoprim, Sulfamethoxazole Drug Combination)
SB  - IM
MH  - Amphotericin B/administration & dosage/therapeutic use
MH  - Anti-Bacterial Agents/administration & dosage/therapeutic use
MH  - Antifungal Agents/therapeutic use
MH  - Brazil/epidemiology
MH  - Humans
MH  - Liver Transplantation/*adverse effects
MH  - Male
MH  - Middle Aged
MH  - Paracoccidioides
MH  - Paracoccidioidomycosis/*diagnosis/*drug therapy/epidemiology
MH  - *Transplant Recipients
MH  - Trimethoprim, Sulfamethoxazole Drug Combination/administration & 
      dosage/therapeutic use
PMC - PMC6838593
EDAT- 2019/09/14 06:00
MHDA- 2020/03/19 06:00
PMCR- 2020/11/01
CRDT- 2019/09/14 06:00
PHST- 2019/09/14 06:00 [pubmed]
PHST- 2020/03/19 06:00 [medline]
PHST- 2019/09/14 06:00 [entrez]
PHST- 2020/11/01 00:00 [pmc-release]
AID - tpmd181008 [pii]
AID - 10.4269/ajtmh.18-1008 [doi]
PST - ppublish
SO  - Am J Trop Med Hyg. 2019 Nov;101(5):1100-1106. doi: 10.4269/ajtmh.18-1008.