PMID- 31521660
OWN - NLM
STAT- MEDLINE
DCOM- 20200605
LR  - 20200605
IS  - 1879-0003 (Electronic)
IS  - 0141-8130 (Linking)
VI  - 142
DP  - 2020 Jan 1
TI  - Encapsulation of Bunium persicum essential oil using chitosan nanopolymer: 
      Preparation, characterization, antifungal assessment, and thermal stability.
PG  - 172-180
LID - S0141-8130(19)35103-7 [pii]
LID - 10.1016/j.ijbiomac.2019.09.089 [doi]
AB  - The present study reports the antifungal, aflatoxin B(1) inhibitory, and free 
      radical scavenging activity of chitosan-based nanoencapsulatedBunium persicum 
      Boiss. essential oil (Ne-BPEO). The chemical profile ofBPEO was identified 
      through Gas chromatography mass spectrometry analysis where cuminaldehyde 
      (21.23%), sabinene (14.66%), and gamma-terpinen (12.49%) were identified as the major 
      compounds. Ne-BPEO was prepared using chitosan and characterised by Scanning 
      electron microscope (SEM), Atomic force microscope (AFM), Fourier-transform 
      infrared spectroscopy (FTIR), and X-ray diffraction (XRD) assay. Ne-BPEO 
      completely inhibited the growth and aflatoxin B(1) production at a concentration 
      of 0.3 muL/mL. The antifungal and aflatoxin B(1) inhibitory effects were related 
      to decreasing in ergosterol content, leakage of membrane ions (Ca(2+), K(+), and 
      Mg(2+)), impairment in carbohydrate catabolism, and functioning of ver-1 gene of 
      A. flavus exposed to Ne-BPEO over the control. In addition, Ne-BPEO exhibited 
      promising free radical scavenging activity through DPPH assay (IC(50) 
      12.64 muL/mL) with high thermo-stability. Therefore, chitosan could be used as a 
      carrier agent of plant-based preservative to enhance the shelf-life of food 
      products against A. flavus and aflatoxin B(1) contamination.
CI  - Copyright (c) 2019 Elsevier B.V. All rights reserved.
FAU - Yadav, Amrita
AU  - Yadav A
AD  - Centre of Advanced Study in Botany, Institute of Science, Banaras Hindu 
      University, Varanasi 221005, India.
FAU - Kujur, Anupam
AU  - Kujur A
AD  - Centre of Advanced Study in Botany, Institute of Science, Banaras Hindu 
      University, Varanasi 221005, India.
FAU - Kumar, Akshay
AU  - Kumar A
AD  - Centre of Advanced Study in Botany, Institute of Science, Banaras Hindu 
      University, Varanasi 221005, India.
FAU - Singh, Prem Pratap
AU  - Singh PP
AD  - Centre of Advanced Study in Botany, Institute of Science, Banaras Hindu 
      University, Varanasi 221005, India.
FAU - Gupta, Vishal
AU  - Gupta V
AD  - Centre of Advanced Study in Botany, Institute of Science, Banaras Hindu 
      University, Varanasi 221005, India.
FAU - Prakash, Bhanu
AU  - Prakash B
AD  - Centre of Advanced Study in Botany, Institute of Science, Banaras Hindu 
      University, Varanasi 221005, India. Electronic address: bprakash@bhu.ac.in.
LA  - eng
PT  - Journal Article
DEP - 20190912
PL  - Netherlands
TA  - Int J Biol Macromol
JT  - International journal of biological macromolecules
JID - 7909578
RN  - 0 (Antifungal Agents)
RN  - 0 (Benzaldehydes)
RN  - 0 (Bicyclic Monoterpenes)
RN  - 0 (Cyclohexane Monoterpenes)
RN  - 0 (Cymenes)
RN  - 0 (Oils, Volatile)
RN  - 0 (Plant Extracts)
RN  - 0 (Plant Oils)
RN  - 4YGF4PQP49 (gamma-terpinene)
RN  - 7D1TL44GPC (sabinene)
RN  - 9012-76-4 (Chitosan)
RN  - 9N2N2Y55MH (Aflatoxin B1)
RN  - O0893NC35F (cuminaldehyde)
SB  - IM
MH  - Aflatoxin B1/metabolism
MH  - Antifungal Agents/*pharmacology
MH  - Apiaceae/*chemistry
MH  - Aspergillus flavus/drug effects
MH  - Benzaldehydes/isolation & purification
MH  - Bicyclic Monoterpenes/isolation & purification
MH  - Chitosan/*pharmacology
MH  - Cyclohexane Monoterpenes/isolation & purification
MH  - Cymenes/isolation & purification
MH  - Gas Chromatography-Mass Spectrometry
MH  - Nanoparticles/*chemistry
MH  - Oils, Volatile/*chemistry/pharmacology
MH  - Plant Extracts/*chemistry
MH  - Plant Oils/chemistry
MH  - X-Ray Diffraction
OTO - NOTNLM
OT  - Aflatoxin B(1)
OT  - Bunium persicum essential oil
OT  - Chitosan nanopolymer
EDAT- 2019/09/16 06:00
MHDA- 2020/06/06 06:00
CRDT- 2019/09/16 06:00
PHST- 2019/07/04 00:00 [received]
PHST- 2019/09/03 00:00 [revised]
PHST- 2019/09/11 00:00 [accepted]
PHST- 2019/09/16 06:00 [pubmed]
PHST- 2020/06/06 06:00 [medline]
PHST- 2019/09/16 06:00 [entrez]
AID - S0141-8130(19)35103-7 [pii]
AID - 10.1016/j.ijbiomac.2019.09.089 [doi]
PST - ppublish
SO  - Int J Biol Macromol. 2020 Jan 1;142:172-180. doi: 10.1016/j.ijbiomac.2019.09.089. 
      Epub 2019 Sep 12.