PMID- 31523361
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20201001
IS  - 1944-8171 (Print)
IS  - 1944-8171 (Electronic)
IS  - 1944-8171 (Linking)
VI  - 11
IP  - 4
DP  - 2019
TI  - Association between obesity and craniofacial muscles sensitivity: an experimental 
      study in pain-free subjects.
PG  - 138-148
AB  - The objective of this study was to investigate if any association exists between 
      obesity and muscle sensitivity in the craniofacial region of healthy individuals 
      with different body mass index (BMI). The study was designed as a parallel single 
      blinded investigation approved by the North Denmark Region Committee on Health 
      Research Ethics (N-20180029). Written informed consent was obtained from all 
      participants. Subjects were divided into normal BMI (18.5-24.9 kg/m(2)) and high 
      BMI (>/=25.0 kg/m(2)). Measurement of body composition parameters was followed by 
      pressure algometry applied on skin overlying masseter and temporalis muscles 
      before and after a cold pressor test (CPT). Deltoid muscle was used as a 
      reference point. Statistical analysis was carried out to investigate the 
      difference in mean pressure pain threshold (PPT) values and the conditioned pain 
      modulation (CPM) effect. Forty subjects were included (20 normal BMI and 20 high 
      BMI). No significant difference was found in mean PPT values or mean CPM effect 
      between the BMI groups (PPT: masseter P=0.763, temporalis P=0.425, deltoid 
      P=0.595 and CPM effect: masseter P=0.396, temporalis P=0.463, deltoid P=0.484). 
      Mechanical muscle sensitivity and CPM effect were sex-independent. No influence 
      of BMI was identified on mechanical muscle sensitivity in the craniofacial region 
      of healthy individuals.
FAU - Fedders, Sandra Radzimanowski
AU  - Fedders SR
AD  - Department of Health Science and Technology, Faculty of Medicine, Aalborg 
      University Aalborg, Denmark.
FAU - Larsen, Lina Klitgaard
AU  - Larsen LK
AD  - Department of Health Science and Technology, Faculty of Medicine, Aalborg 
      University Aalborg, Denmark.
FAU - Huntjens, Pam
AU  - Huntjens P
AD  - Department of Health Science and Technology, Faculty of Medicine, Aalborg 
      University Aalborg, Denmark.
FAU - Sondrup, Maria Agerboe
AU  - Sondrup MA
AD  - Department of Health Science and Technology, Faculty of Medicine, Aalborg 
      University Aalborg, Denmark.
FAU - Thomsen, Malene Kaasing
AU  - Thomsen MK
AD  - Department of Health Science and Technology, Faculty of Medicine, Aalborg 
      University Aalborg, Denmark.
FAU - Kjaer, Charlotte
AU  - Kjaer C
AD  - Department of Health Science and Technology, Faculty of Medicine, Aalborg 
      University Aalborg, Denmark.
FAU - Clausen, Line Pirk
AU  - Clausen LP
AD  - Department of Health Science and Technology, Faculty of Medicine, Aalborg 
      University Aalborg, Denmark.
FAU - Bujold, Gabrielle
AU  - Bujold G
AD  - Department of Health Science and Technology, Faculty of Medicine, Aalborg 
      University Aalborg, Denmark.
FAU - Gazerani, Parisa
AU  - Gazerani P
AD  - Department of Health Science and Technology, Faculty of Medicine, Aalborg 
      University Aalborg, Denmark.
LA  - eng
PT  - Journal Article
DEP - 20190815
PL  - United States
TA  - Int J Physiol Pathophysiol Pharmacol
JT  - International journal of physiology, pathophysiology and pharmacology
JID - 101521074
PMC - PMC6737431
OTO - NOTNLM
OT  - Obesity
OT  - body mass index
OT  - craniofacial muscles
OT  - pain sensitivity
OT  - pain threshold
COIS- None.
EDAT- 2019/09/17 06:00
MHDA- 2019/09/17 06:01
PMCR- 2019/08/15
CRDT- 2019/09/17 06:00
PHST- 2019/05/01 00:00 [received]
PHST- 2019/07/19 00:00 [accepted]
PHST- 2019/09/17 06:00 [entrez]
PHST- 2019/09/17 06:00 [pubmed]
PHST- 2019/09/17 06:01 [medline]
PHST- 2019/08/15 00:00 [pmc-release]
PST - epublish
SO  - Int J Physiol Pathophysiol Pharmacol. 2019 Aug 15;11(4):138-148. eCollection 
      2019.