PMID- 31528284
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20200930
IS  - 2000-9666 (Print)
IS  - 2000-9666 (Electronic)
IS  - 2000-9666 (Linking)
VI  - 9
IP  - 4
DP  - 2019
TI  - Ecstasy induced acute systolic heart failure and Non-Ischemic Cardiomyopathy in a 
      young female: a rare case report and literature review.
PG  - 336-339
LID - 10.1080/20009666.2019.1650593 [doi]
AB  - Ecstasy or 3,4-methylenedioxymethamphetamine (MDMA) is an illicit recreational 
      drug. Effects include euphoria, increased sensory awareness, and central 
      stimulation. Although various arrhythmias, as well as dilated cardiomyopathy, 
      have been previously noted to occur with chronic use, cardiac toxicities are 
      seldom reported in an acute setting. Herein, we present a 28-year-old female 
      patient with no prior medical condition that presented to the Emergency 
      Department with chest pain following intake of MDMA. Electrocardiographic 
      findings, as well as laboratories, were suggestive of possible Acute Non-ST 
      elevation myocardial infarction. Upon admission, cardiac catheterization revealed 
      patent coronary arteries. Stark regional wall motion abnormalities were observed 
      along with reduced ejection fraction. Acute systolic heart failure was treated 
      with standard medical management. Subsequent reassessment of ventricular function 
      with Echocardiography revealed marked improvement. This article describes a case 
      of MDMA induced heart failure, including details of evaluation, management, and 
      monitoring of patient progress. It brings further attention to potential acute 
      harmful effects of MDMA on cardiac function and viability.
FAU - Kafle, Paritosh
AU  - Kafle P
AUID- ORCID: 0000-0002-4345-1392
AD  - Department of Internal Medicine, Interfaith Medical Center, Brooklyn, NY, USA.
FAU - Shrestha, Binav
AU  - Shrestha B
AUID- ORCID: 0000-0002-6839-4726
AD  - Department of Internal Medicine, Interfaith Medical Center, Brooklyn, NY, USA.
FAU - Mandal, Amrendra
AU  - Mandal A
AUID- ORCID: 0000-0002-5873-5443
AD  - Department of Internal Medicine, Interfaith Medical Center, Brooklyn, NY, USA.
FAU - Sharma, Dikshya
AU  - Sharma D
AD  - Department of Internal Medicine, Maimonides Medical Center, Brooklyn, NY, USA.
FAU - Bhandari, Manjul
AU  - Bhandari M
AD  - Department of Internal Medicine, Interfaith Medical Center, Brooklyn, NY, USA.
FAU - Amgai, Birendra
AU  - Amgai B
AD  - Department of Internal Medicine, Interfaith Medical Center, Brooklyn, NY, USA.
FAU - Khalid, Mazin
AU  - Khalid M
AUID- ORCID: 0000-0003-4868-4299
AD  - Department of Internal Medicine, Interfaith Medical Center, Brooklyn, NY, USA.
FAU - Sidhu, Jasdeep S
AU  - Sidhu JS
AUID- ORCID: 0000-0003-2790-2437
AD  - Department of Internal Medicine, Interfaith Medical Center, Brooklyn, NY, USA.
FAU - Solaimanzadeh, Isaac
AU  - Solaimanzadeh I
AD  - Department of Internal Medicine, Interfaith Medical Center, Brooklyn, NY, USA.
FAU - Gayam, Vijay
AU  - Gayam V
AUID- ORCID: 0000-0001-5194-9134
AD  - Department of Internal Medicine, Interfaith Medical Center, Brooklyn, NY, USA.
FAU - Surana, Rahul
AU  - Surana R
AD  - Department of Internal Medicine, Interfaith Medical Center, Brooklyn, NY, USA.
FAU - Dufresne, Alix
AU  - Dufresne A
AD  - Department of Cardiology, Interfaith Medical Center, Brooklyn, NY, USA.
LA  - eng
PT  - Case Reports
DEP - 20190905
PL  - United States
TA  - J Community Hosp Intern Med Perspect
JT  - Journal of community hospital internal medicine perspectives
JID - 101601396
PMC - PMC6735291
OTO - NOTNLM
OT  - Ecstasy
OT  - heart failure
OT  - non-ST elevation MI
OT  - non-ischemic cardiomyopathy
OT  - systolic dysfunction
EDAT- 2019/09/19 06:00
MHDA- 2019/09/19 06:01
PMCR- 2019/09/05
CRDT- 2019/09/19 06:00
PHST- 2019/06/15 00:00 [received]
PHST- 2019/07/25 00:00 [accepted]
PHST- 2019/09/19 06:00 [entrez]
PHST- 2019/09/19 06:00 [pubmed]
PHST- 2019/09/19 06:01 [medline]
PHST- 2019/09/05 00:00 [pmc-release]
AID - 1650593 [pii]
AID - 10.1080/20009666.2019.1650593 [doi]
PST - epublish
SO  - J Community Hosp Intern Med Perspect. 2019 Sep 5;9(4):336-339. doi: 
      10.1080/20009666.2019.1650593. eCollection 2019.