PMID- 31543202
OWN - NLM
STAT- MEDLINE
DCOM- 20200225
LR  - 20200501
IS  - 2213-3763 (Electronic)
IS  - 0019-4832 (Print)
IS  - 0019-4832 (Linking)
VI  - 71
IP  - 3
DP  - 2019 May-Jun
TI  - Clinical significance of bendopnea in heart failure-Systematic review and 
      meta-analysis.
PG  - 277-283
LID - S0019-4832(19)30067-7 [pii]
LID - 10.1016/j.ihj.2019.05.001 [doi]
AB  - BACKGROUND: Bendopnea is a symptom mediated by increased ventricular filling 
      pressure during bending forward. Presence of bendopnea in patients can be easily 
      evaluated without additional maneuver in several countries whose norms, habits, 
      culture, and occupation relates to a higher frequency of bending forward. This 
      information may prove valuable in routine clinical practice. We aimed to analyze 
      the latest evidence on bendopnea in order to further define the clinical 
      significance of this symptom. METHODS: We performed a comprehensive search on 
      bendopnea in heart failure from inception up until January 2019 through PubMed, 
      EuropePMC, EBSCOhost, Cochrane Central Database, and ClinicalTrials.gov. RESULTS: 
      There were 283 patients (31.76%) who have bendopnea, and a total of 891 patients 
      from six studies were included. Bendopnea was associated with the presence of 
      dyspnea [odds ratio (OR) 69.70 (17.35-280.07); <0.001], orthopnea [OR 3.02 
      (2.02-4.52); <0.001], paroxysmal nocturnal dyspnea [OR 2.76 (1.76-4.32); <0.001], 
      and abdominal fullness [OR 7.50 (4.15-13.58); <0.001]. Association with elevated 
      jugular venous pressure was shown in two studies. New York Heart Association 
      (NYHA) functional class IV was more prevalent in patients with bendopnea [OR 7.58 
      (4.35-13.22); <0.001]. Bendopnea was also associated with increased mortality [OR 
      2.21 (1.34-3.66); 0.002]. CONCLUSION: Bendopnea is associated with the presence 
      of several signs and symptoms. This study also showed that bendopnea is one of 
      the signs and symptoms of advanced heart failure associated with increased 
      mortality. However, owing to the limited number of studies, further investigation 
      is needed before drawing a definite conclusion.
CI  - Copyright (c) 2019 Cardiological Society of India. Published by Elsevier B.V. All 
      rights reserved.
FAU - Pranata, Raymond
AU  - Pranata R
AD  - Faculty of Medicine, Universitas Pelita Harapan, Tangerang, Indonesia. Electronic 
      address: raymond_pranata@hotmail.com.
FAU - Yonas, Emir
AU  - Yonas E
AD  - Faculty of Medicine, Universitas YARSI, Jakarta, Indonesia. Electronic address: 
      E_yonas@windowslive.com.
FAU - Chintya, Veresa
AU  - Chintya V
AD  - Faculty of Medicine, Universitas Kristen Krida Wacana, Jakarta, Indonesia. 
      Electronic address: veresa.vc@gmail.com.
FAU - Alkatiri, Amir Aziz
AU  - Alkatiri AA
AD  - Department of Cardiology and Vascular Medicine, Faculty of Medicine Universitas 
      Indonesia, National Cardiovascular Center Harapan Kita, Jakarta, Indonesia. 
      Electronic address: amiralkatiri@gmail.com.
FAU - Budi Siswanto, Bambang
AU  - Budi Siswanto B
AD  - Department of Cardiology and Vascular Medicine, Faculty of Medicine Universitas 
      Indonesia, National Cardiovascular Center Harapan Kita, Jakarta, Indonesia. 
      Electronic address: bambbs@gmail.com.
LA  - eng
PT  - Journal Article
PT  - Meta-Analysis
PT  - Systematic Review
DEP - 20190603
PL  - India
TA  - Indian Heart J
JT  - Indian heart journal
JID - 0374675
SB  - IM
MH  - Dyspnea/*etiology/physiopathology
MH  - Heart Failure/*complications/physiopathology
MH  - Humans
MH  - Posture/*physiology
MH  - Prevalence
PMC - PMC6796800
OTO - NOTNLM
OT  - Advanced heart failure
OT  - Bendopnea
OT  - Dyspnea
OT  - Heart failure
OT  - Signs and symptoms
EDAT- 2019/09/24 06:00
MHDA- 2020/02/26 06:00
PMCR- 2020/05/01
CRDT- 2019/09/24 06:00
PHST- 2019/02/08 00:00 [received]
PHST- 2019/04/10 00:00 [revised]
PHST- 2019/05/28 00:00 [accepted]
PHST- 2019/09/24 06:00 [entrez]
PHST- 2019/09/24 06:00 [pubmed]
PHST- 2020/02/26 06:00 [medline]
PHST- 2020/05/01 00:00 [pmc-release]
AID - S0019-4832(19)30067-7 [pii]
AID - 10.1016/j.ihj.2019.05.001 [doi]
PST - ppublish
SO  - Indian Heart J. 2019 May-Jun;71(3):277-283. doi: 10.1016/j.ihj.2019.05.001. Epub 
      2019 Jun 3.