PMID- 31546555
OWN - NLM
STAT- MEDLINE
DCOM- 20200518
LR  - 20200518
IS  - 1998-3689 (Electronic)
IS  - 0301-4738 (Print)
IS  - 0301-4738 (Linking)
VI  - 67
IP  - 10
DP  - 2019 Oct
TI  - Spontaneous formation and closure of full thickness macular hole after treatment 
      with anti-vascular endothelial growth factor therapy in polypoidal choroidal 
      vasculopathy.
PG  - 1756-1758
LID - 10.4103/ijo.IJO_1597_18 [doi]
AB  - Full-thickness macular hole (FTMH) formation in Polypoidal choroidal vasculopathy 
      (PCV) after intravitreal anti-vascular endothelial growth factor (anti-VEGF) 
      treatment is a rare complication. Spontaneous closure of FTMH following anti-VEGF 
      therapy has not been described in PCV till date. We present a case of Asian woman 
      with PCV who developed a FTMH following treatment with intra-vitreal anti-VEGF 
      injections which subsequently closed spontaneously on further course of 
      treatment.
FAU - Sethia, Abhishek
AU  - Sethia A
AD  - Department of Vitreo-Retina, Giridhar Eye Institute, Ernakulam, Kochi, Kerala, 
      India.
FAU - Sheth, Jay
AU  - Sheth J
AD  - Department of Vitreo-Retina, Giridhar Eye Institute, Ernakulam, Kochi, Kerala, 
      India.
FAU - Gopalakrishnan, Mahesh
AU  - Gopalakrishnan M
AD  - Department of Vitreo-Retina, Giridhar Eye Institute, Ernakulam, Kochi, Kerala, 
      India.
FAU - Anantharaman, Giridhar
AU  - Anantharaman G
AD  - Department of Vitreo-Retina, Giridhar Eye Institute, Ernakulam, Kochi, Kerala, 
      India.
LA  - eng
PT  - Case Reports
PL  - India
TA  - Indian J Ophthalmol
JT  - Indian journal of ophthalmology
JID - 0405376
RN  - 0 (Angiogenesis Inhibitors)
RN  - 2S9ZZM9Q9V (Bevacizumab)
RN  - EC 2.7.10.1 (Receptors, Vascular Endothelial Growth Factor)
SB  - IM
MH  - Angiogenesis Inhibitors/administration & dosage
MH  - Bevacizumab/*administration & dosage
MH  - Choroid/*blood supply
MH  - Choroid Diseases/complications/diagnosis/*drug therapy
MH  - Female
MH  - Fluorescein Angiography
MH  - Fundus Oculi
MH  - Humans
MH  - Intravitreal Injections
MH  - Middle Aged
MH  - Polyps/complications/diagnosis/*drug therapy
MH  - Receptors, Vascular Endothelial Growth Factor/antagonists & inhibitors
MH  - Remission, Spontaneous
MH  - Retinal Perforations/*diagnosis/etiology
MH  - Tomography, Optical Coherence
PMC - PMC6786155
OTO - NOTNLM
OT  - Full-thickness macular hole
OT  - intra-vitreal anti-vascular endothelial growth factor
OT  - polypoidal choroidal vasculopathy
COIS- There are no conflicts of interest.
EDAT- 2019/09/25 06:00
MHDA- 2020/05/19 06:00
PMCR- 2019/10/01
CRDT- 2019/09/25 06:00
PHST- 2019/09/25 06:00 [entrez]
PHST- 2019/09/25 06:00 [pubmed]
PHST- 2020/05/19 06:00 [medline]
PHST- 2019/10/01 00:00 [pmc-release]
AID - IndianJOphthalmol_2019_67_10_1756_267391 [pii]
AID - IJO-67-1756 [pii]
AID - 10.4103/ijo.IJO_1597_18 [doi]
PST - ppublish
SO  - Indian J Ophthalmol. 2019 Oct;67(10):1756-1758. doi: 10.4103/ijo.IJO_1597_18.