PMID- 31552590 OWN - NLM STAT- MEDLINE DCOM- 20201013 LR - 20201013 IS - 1863-6713 (Electronic) IS - 1863-6705 (Linking) VI - 68 IP - 5 DP - 2020 May TI - Moderate ischemic mitral incompetence: does it worth more ischemic time? PG - 492-498 LID - 10.1007/s11748-019-01212-5 [doi] AB - OBJECTIVES: Ischemic mitral regurgitation (IMR) is a common finding following myocardial infarction or ischemia. Management of moderate IMR is still a hot topic. Adding mitral valve repair (MVr) to coronary artery bypass grafting (CABG) is questionable. The goal of this study was to assess and compare short-term clinical and echocardiographic results of moderate IMR treated by CABG alone versus another group of patients treated by CABG plus MVr. METHODS: Eighty consecutive patients with ischemic heart disease (IHD) and moderate IMR were divided randomly into two equal groups: group I (40) had only CABG and group II (40) had CABG plus MVr. Patients were evaluated at 1-week, 3-months and 1-year intervals postoperatively. RESULTS: After 1-year follow-up, our study revealed statistically significant improvement in the grade of mitral regurgitation (MR) in group II than group I. The mean value for effective regurgitant orifice area (EROA) was 0.22 +/- 0.13 for group I versus 0.03 +/- 0.03 for group II (P = 0.001) and for vena contracta (VC), it was 3.8 +/- 2.24 for group I versus 0.4 +/- 0.49 for group II (P = 0.000). There was also a significant reduction in the New York Heart Association (NYHA) functional class in both groups. CONCLUSIONS: MVr can be performed safely and concomitantly with CABG in patients having moderate IMR, and its addition to CABG have significant short-term impact on clinical or echocardiographic outcome of patients. FAU - El-Hag-Aly, Mohammed A AU - El-Hag-Aly MA AD - Cardiothoracic Surgery Department, Faculty of Medicine, Menoufia University, Yassin Abdel Ghaffar Street, Shebin El-Kom, 32511, Menoufia, Egypt. FAU - El Swaf, Yasser F AU - El Swaf YF AD - Cardiothoracic Surgery Department, Mahalla Cardiac Institute, Mahalla, Gharbia, Egypt. FAU - Elkassas, Marwan H AU - Elkassas MH AD - Cardiothoracic Surgery Department, Faculty of Medicine, Suez Canal University, Suez, Egypt. FAU - Hagag, Mohamed G AU - Hagag MG AUID- ORCID: 0000-0002-1506-888X AD - Cardiothoracic Surgery Department, Faculty of Medicine, Menoufia University, Yassin Abdel Ghaffar Street, Shebin El-Kom, 32511, Menoufia, Egypt. mohamedhagag@med.menofia.edu.eg. FAU - Allam, Heba Khodary AU - Allam HK AD - Public Health and Community Medicine Department, Faculty of Medicine, Menoufia University, Shebin El-Kom, Menoufia, Egypt. LA - eng PT - Comparative Study PT - Journal Article PT - Multicenter Study PT - Randomized Controlled Trial DEP - 20190924 PL - Japan TA - Gen Thorac Cardiovasc Surg JT - General thoracic and cardiovascular surgery JID - 101303952 SB - IM MH - Aged MH - *Coronary Artery Bypass MH - Coronary Artery Disease/complications/*surgery MH - Echocardiography MH - Female MH - Follow-Up Studies MH - Humans MH - Male MH - Middle Aged MH - Mitral Valve Insufficiency/diagnostic imaging/etiology/*surgery MH - Myocardial Ischemia/complications/*surgery MH - Postoperative Period MH - Prospective Studies MH - Treatment Outcome OTO - NOTNLM OT - Cardiac surgical procedures OT - Coronary artery bypass OT - Mitral valve insufficiency OT - Myocardial ischemia OT - Valve repair EDAT- 2019/09/26 06:00 MHDA- 2020/10/21 06:00 CRDT- 2019/09/26 06:00 PHST- 2019/02/21 00:00 [received] PHST- 2019/09/17 00:00 [accepted] PHST- 2019/09/26 06:00 [pubmed] PHST- 2020/10/21 06:00 [medline] PHST- 2019/09/26 06:00 [entrez] AID - 10.1007/s11748-019-01212-5 [pii] AID - 10.1007/s11748-019-01212-5 [doi] PST - ppublish SO - Gen Thorac Cardiovasc Surg. 2020 May;68(5):492-498. doi: 10.1007/s11748-019-01212-5. Epub 2019 Sep 24.