PMID- 31556700
OWN - NLM
STAT- MEDLINE
DCOM- 20200528
LR  - 20200528
IS  - 1938-2707 (Electronic)
IS  - 0009-9228 (Linking)
VI  - 58
IP  - 14
DP  - 2019 Dec
TI  - Short-Term High-Flow Nasal Cannula for Moderate to Severe Bronchiolitis Is 
      Effective in a General Pediatric Ward.
PG  - 1522-1527
LID - 10.1177/0009922819877881 [doi]
AB  - We examined the clinical and physiological benefits of heated humidified 
      high-flow nasal cannula (HHHFNC) in treating pediatric bronchiolitis in a general 
      pediatric ward. Children aged 0 to 2 years, hospitalized with moderate to severe 
      bronchiolitis, were connected to HHHFNC. Each child was evaluated at 4- to 
      10-hour intervals, both on and off the device, using the Wang et al Bronchiolitis 
      Severity score and transcutaneous CO(2) monitor. Sixteen children were included 
      in the final analysis. The Bronchiolitis Severity score improved by 3 points 
      during the first and second intervals (P = .001). Transcutaneous CO(2) values 
      were reduced by an average 8.7 mm Hg (P = .001). No adverse effects were noted in 
      children connected to the device. The HHHFNC device used in a general pediatric 
      ward setting served as a safe and efficacious tool in treating moderate to severe 
      bronchiolitis. Immediate clinical and physiological improvement was observed and 
      maintained 1 to 4 hours after disconnection from the device.
FAU - Sachs, Nimrod
AU  - Sachs N
AUID- ORCID: 0000-0003-4811-689X
AD  - Schneider Children's Medical Center, Petah Tikva, Israel.
AD  - Tel-Aviv University, Tel Aviv, Israel.
FAU - Rom, Eran
AU  - Rom E
AD  - Schneider Children's Medical Center, Petah Tikva, Israel.
AD  - Tel-Aviv University, Tel Aviv, Israel.
FAU - Schonfeld, Tommy
AU  - Schonfeld T
AD  - Schneider Children's Medical Center, Petah Tikva, Israel.
FAU - Gavish, Rachel
AU  - Gavish R
AD  - Schneider Children's Medical Center, Petah Tikva, Israel.
AD  - Tel-Aviv University, Tel Aviv, Israel.
FAU - Berger, Itay
AU  - Berger I
AD  - Schneider Children's Medical Center, Petah Tikva, Israel.
FAU - Krause, Irit
AU  - Krause I
AD  - Schneider Children's Medical Center, Petah Tikva, Israel.
AD  - Tel-Aviv University, Tel Aviv, Israel.
LA  - eng
PT  - Journal Article
DEP - 20190926
PL  - United States
TA  - Clin Pediatr (Phila)
JT  - Clinical pediatrics
JID - 0372606
SB  - IM
MH  - Administration, Intranasal
MH  - Bronchiolitis/*physiopathology/therapy
MH  - Catheters
MH  - Child
MH  - Female
MH  - Hospitals, Pediatric
MH  - Humans
MH  - Infant
MH  - Infant, Newborn
MH  - Male
MH  - Noninvasive Ventilation/*methods
MH  - Oxygen Inhalation Therapy/*methods
MH  - Treatment Outcome
OTO - NOTNLM
OT  - bronchiolitis
OT  - bronchiolitis score
OT  - heated humidified high-flow nasal cannula
OT  - pediatric
OT  - transcutaneous CO2
EDAT- 2019/09/27 06:00
MHDA- 2020/05/29 06:00
CRDT- 2019/09/27 06:00
PHST- 2019/09/27 06:00 [pubmed]
PHST- 2020/05/29 06:00 [medline]
PHST- 2019/09/27 06:00 [entrez]
AID - 10.1177/0009922819877881 [doi]
PST - ppublish
SO  - Clin Pediatr (Phila). 2019 Dec;58(14):1522-1527. doi: 10.1177/0009922819877881. 
      Epub 2019 Sep 26.